Gasdermin E mediates photoreceptor damage by all-trans-retinal in the mouse retina

Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis

(2020) Sannula Kesavardhana et al.   Annual Review of Immunology

Activation of JNK signaling promotes all-trans-retinal–induced photoreceptor apoptosis in mice

(2020) Chunyan Liao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

(2020) Junwei Hou et al.   NATURE CELL BIOLOGY

The Coming Decade of Cell Death Research: Five Riddles

(2019) Douglas R. Green   CELL

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

(2019) Corey Rogers et al.   Nature Communications

Gasdermins and their role in immunity and inflammation

(2019) Pontus Orning et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis

(2019) Dan A. Erkes et al.   Cancer Discovery

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina

(2018) Zhan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Programmed necrosis in inflammation: Toward identification of the effector molecules

(2016) D. Wallach et al.   SCIENCE

All-trans-retinal dimer formation alleviates the cytotoxicity of all-trans-retinal in human retinal pigment epithelial cells

(2016) Jie Li et al.   TOXICOLOGY

Retinoids and Retinal Diseases

(2016) Philip D. Kiser et al.   Annual Review of Vision Science

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3

(2014) Huayi Wang et al.   MOLECULAR CELL

Inflammatory caspases are innate immune receptors for intracellular LPS

(2014) Jianjin Shi et al.   NATURE

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

(2013) Xin Chen et al.   CELL RESEARCH

Chemistry of the Retinoid (Visual) Cycle

(2013) Philip D. Kiser et al.   CHEMICAL REVIEWS

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

(2013) Zhenyu Cai et al.   NATURE CELL BIOLOGY

Vitamin A Metabolism in Rod and Cone Visual Cycles

(2012) John C. Saari   Annual Review of Nutrition

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Reduction of All-trans-retinal in Vertebrate Rod Photoreceptors Requires the Combined Action of RDH8 and RDH12

(2012) Chunhe Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer

(2012) Faraz Quazi et al.   Nature Communications

Mechanism of All-trans-retinal Toxicity with Implications for Stargardt Disease and Age-related Macular Degeneration

(2011) Yu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice

(2009) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance

(2008) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY