Activated Factor XI is Increased in Plasma in Response to Surgical Trauma but not to Recombinant Activated FVII-Induced Thrombin Formation

Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty

(2020) Jeffrey I. Weitz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Factor XI inhibition fulfilling the optimal expectations for ideal anticoagulation

(2019) Orsolya Székely et al.   EXPERT OPINION ON EMERGING DRUGS

Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial

(2019) Christina U. Lorentz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increased Activated Protein C Response Rates Reduce the Thrombotic Risk of Factor V Leiden Carriers but not of Prothrombin 20210G>A Carriers

(2019) Heiko Rühl et al.   CIRCULATION RESEARCH

Characterization of circulating thrombin in patients with septic shock: a prospective observational study

(2019) Tobias Becher et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Tissue Factor

(2018) Steven P. Grover et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

In vivo thrombin generation and subsequent APC formation are increased in factor V Leiden carriers

(2018) Heiko Rühl et al.   BLOOD

Coagulation factor XII in thrombosis and inflammation

(2018) Coen Maas et al.   BLOOD

An update on factor XI structure and function

(2018) Bassem M. Mohammed et al.   THROMBOSIS RESEARCH

Correlation between factor (F)XIa, FIXa and tissue factor and trauma severity

(2017) Shannon M. Prior et al.   Journal of Trauma and Acute Care Surgery

Factor XII Contact Activation

(2017) Clément Naudin et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Nucleic acids as cofactors for factor XI and prekallikrein activation: Different roles for high-molecular-weight kininogen

(2017) Ivan Ivanov et al.   THROMBOSIS AND HAEMOSTASIS

Correlation between factor (F)XIa, FIXa and tissue factor and trauma severity

(2017) Shannon M. Prior et al.   Journal of Trauma and Acute Care Surgery

Factor XIa and Thrombin Generation Are Elevated in Patients with Acute Coronary Syndrome and Predict Recurrent Cardiovascular Events

(2016) Rinske Loeffen et al.   PLoS One

Why factor XI deficiency is a clinical concern

(2016) Allison P. Wheeler et al.   Expert Review of Hematology

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

(2015) Harry R. Büller et al.   NEW ENGLAND JOURNAL OF MEDICINE

Label-Free Kinetic Studies of Hemostasis-Related Biomarkers Including D-Dimer Using Autologous Serum Transfusion

(2015) Heiko Rühl et al.   PLoS One

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

(2014) A. Matafonov et al.   BLOOD

Rare bleeding disorders - bleeding assessment tools, laboratory aspects and phenotype and therapy of FXI deficiency

(2014) P. James et al.   HAEMOPHILIA

Impact of Hormone-Associated Resistance to Activated Protein C on the Thrombotic Potential of Oral Contraceptives: A Prospective Observational Study

(2014) Heiko Rühl et al.   PLoS One

Increased factor XIa levels in patients with a first acute myocardial infarction: The introduction of a new thrombin generation based factor XIa assay

(2014) R. Loeffen et al.   THROMBOSIS RESEARCH

The dimeric structure of factor XI and zymogen activation

(2013) Y. Geng et al.   BLOOD

Factor XI anion-binding sites are required for productive interactions with polyphosphate

(2013) Y. Geng et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Thrombin inhibition profiles in healthy individuals and thrombophilic patients

(2012) Ursula Harbrecht et al.   THROMBOSIS AND HAEMOSTASIS

Profiling of Active Thrombin in Human Blood by Supramolecular Complexes

(2011) Jens Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activation of factor XI by products of prothrombin activation

(2011) A. Matafonov et al.   BLOOD

Polyphosphate is a cofactor for the activation of factor XI by thrombin

(2011) S. H. Choi et al.   BLOOD

Thrombin generation tests

(2011) Elisabetta Castoldi et al.   THROMBOSIS RESEARCH

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

(2010) Q. Cheng et al.   BLOOD

Structure and function of factor XI

(2010) J. Emsley et al.   BLOOD

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL