A Novel Sialoglycopeptide from Gadus morhua Eggs Prevents Liver Fibrosis Induced by CCl4 via Downregulating FXR/FGF15 and TLR4/TGF-β/Smad Pathways

Novel ι-Carrageenan Tetrasaccharide Alleviates Liver Lipid Accumulation via the Bile Acid–FXR–SHP/PXR Pathway to Regulate Cholesterol Conversion and Fatty Acid Metabolism in Insulin-Resistant Mice

(2021) Yanqi Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Isolation and Characterization of a Novel Sialoglycopeptide Promoting Osteogenesis from Gadus morhua Eggs

(2020) Zhiliang Hei et al.   MOLECULES

Chronic Alcohol Consumption Increased Bile Acid Levels in Enterohepatic Circulation and Reduced Efficacy of Irinotecan

(2020) Xia Gong et al.   ALCOHOL AND ALCOHOLISM

Eicosapentaenoic Acid-Enriched Phosphoethanolamine Plasmalogens Alleviated Atherosclerosis by Remodeling Gut Microbiota to Regulate Bile Acid Metabolism in LDLR–/– Mice

(2020) Lin Ding et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bile Acids as Metabolic Regulators and Nutrient Sensors

(2019) John Y. L. Chiang et al.   Annual Review of Nutrition

Hepatic cholesterol accumulation ascribed to the activation of ileum Fxr-Fgf15 pathway inhibiting hepatic Cyp7a1 in high-fat diet-induced obesity rats

(2019) Yingting Duan et al.   LIFE SCIENCES

Natural Products for Prevention and Treatment of Chemical-Induced Liver Injuries

(2018) Xiao Meng et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Effect of celastrol on toll‑like receptor 4‑mediated inflammatory response in free fatty acid‑induced HepG2 cells

(2018) Li‑Ping Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Liuweiwuling tablets attenuate BDL-induced hepatic fibrosis via modulation of TGF-β/Smad and NF-κB signaling pathways

(2018) Huimin Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inducible knockdown of procollagen I protects mice from liver fibrosis and leads to dysregulated matrix genes and attenuated inflammation

(2018) Olena Molokanova et al.   MATRIX BIOLOGY

Liver inflammation and fibrosis

(2017) Yukinori Koyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective effects of theasinensin A against carbon tetrachloride-induced liver injury in mice

(2017) Wei-Lun Hung et al.   Food & Function

Sialoglycoprotein isolated from the eggs of Gadus morhua enhances fracture healing in osteoporotic mice

(2017) Qiping Zhan et al.   Food & Function

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis

(2016) Hailiang Liu et al.   JOURNAL OF LIPID RESEARCH

Bile acid profiles in diabetic (db/db) mice and their wild type littermates

(2016) Chang Chen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy

(2016) Chuanyong Guo et al.   Drug Design Development and Therapy

Tlr4 upregulation in the brain accompanies depression- and anxiety-like behaviors induced by a high-cholesterol diet

(2015) Tatyana Strekalova et al.   BRAIN BEHAVIOR AND IMMUNITY

Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity

(2015) Michaela Mueller et al.   JOURNAL OF HEPATOLOGY

Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in rats

(2015) Yong-Zhan Zhen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

(2015) Changtao Jiang et al.   Nature Communications

Potent natural products and herbal medicines for treating liver fibrosis

(2015) Shao-Ru Chen et al.   Chinese Medicine

Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells

(2014) Kengo Tomita et al.   JOURNAL OF HEPATOLOGY

Pleiotropic Roles of Bile Acids in Metabolism

(2013) Thomas Q. de Aguiar Vallim et al.   Cell Metabolism

Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

(2013) Kengo Tomita et al.   HEPATOLOGY

TLR4, rather than TLR2, regulates wound healing through TGF-β and CCL5 expression

(2013) Hiraku Suga et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Modulation of the fecal bile acid profile by gut microbiota in cirrhosis

(2013) Genta Kakiyama et al.   JOURNAL OF HEPATOLOGY

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

(2012) Bo Kong et al.   HEPATOLOGY

Bioactive compounds, antioxidant potential, and hepatoprotective activity of sea cucumber (Holothuria atra) against thioacetamide intoxication in rats

(2012) Amr Y. Esmat et al.   NUTRITION

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

A High-Cholesterol Diet Exacerbates Liver Fibrosis in Mice via Accumulation of Free Cholesterol in Hepatic Stellate Cells

(2011) Toshiaki Teratani et al.   GASTROENTEROLOGY

Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure

(2011) Mitsuhiro Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis

(2010) Tiangang Li et al.   HEPATOLOGY

Chronic intake of a high-cholesterol diet resulted in hepatic steatosis, focal nodular hyperplasia and fibrosis in non-obese mice

(2009) Maho Sumiyoshi et al.   BRITISH JOURNAL OF NUTRITION

Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the united states population

(2009) George N. Ioannou et al.   HEPATOLOGY

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

PHOSPHATIDYLCHOLINE LEVELS AND THEIR FATTY ACID COMPOSITIONS IN SQUID EGG: A COMPARISON STUDY WITH POLLACK ROE AND STURGEON CAVIAR

(2008) QI WANG et al.   JOURNAL OF FOOD LIPIDS