Prediction of the carrier shape effect on particle transport, interaction and deposition in two dry powder inhalers and a mouth-to-G13 human respiratory system: A CFD-DEM study

Inter-species variabilities of droplet transport, size change, and deposition in human and rat respiratory systems: An in silico study

(2021) Hamideh Hayati et al.   JOURNAL OF AEROSOL SCIENCE

Influences of Puff Protocols and Upper Airway Anatomy on Cannabis Pharmacokinetics: A CFPD-PK Study

(2021) Jianan Zhao et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Computational analysis of obstructive disease and cough intensity effects on the mucus transport and clearance in an idealized upper airway model using the volume of fluid method

(2021) Hang Yi et al.   PHYSICS OF FLUIDS

Flow and Particle Modelling of Dry Powder Inhalers: Methodologies, Recent Development and Emerging Applications

(2021) Zhanying Zheng et al.   Pharmaceutics

Bioequivalence assessment of pharmaceutical aerosol products through IVIVC

(2021) Dennis Sandell   ADVANCED DRUG DELIVERY REVIEWS

Nanoparticle-Based Drug Delivery System: The Magic Bullet for the Treatment of Chronic Pulmonary Diseases

(2021) Sheersha Pramanik et al.   MOLECULAR PHARMACEUTICS

Coupled CFD-DEM model for dry powder inhalers simulation: Validation and sensitivity analysis for the main model parameters

(2021) R. Ponzini et al.   POWDER TECHNOLOGY

Prediction of airway deformation effect on pulmonary air-particle dynamics: A numerical study

(2021) Jianan Zhao et al.   PHYSICS OF FLUIDS

Numerical Study on Particle Adhesion in Dry Powder Inhaler Device

(2020) Ryosuke Mitani et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

3D computational modeling of sand erosion in gas-liquid-particle multiphase annular flows in bends

(2020) A. Farokhipour et al.   WEAR

Influence of wind and relative humidity on the social distancing effectiveness to prevent COVID-19 airborne transmission: A numerical study

(2020) Yu Feng et al.   JOURNAL OF AEROSOL SCIENCE

Estimating inter-patient variability of dispersion in dry powder inhalers using CFD-DEM simulations

(2020) Benedict Benque et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Tutorial: Understanding the transport, deposition, and translocation of particles in human respiratory systems using Computational Fluid-Particle Dynamics and Physiologically Based Toxicokinetic models

(2020) Yu Feng et al.   JOURNAL OF AEROSOL SCIENCE

Mucus transport and distribution by steady expiration in an idealized airway geometry

(2019) Rahul R Rajendran et al.   MEDICAL ENGINEERING & PHYSICS

Lung aerosol dynamics of airborne influenza A virus-laden droplets and the resultant immune system responses: An in silico study

(2019) Ahmadreza Haghnegahdar et al.   JOURNAL OF AEROSOL SCIENCE

Numerical simulation of welding fume lung dosimetry

(2019) Jianan Zhao et al.   JOURNAL OF AEROSOL SCIENCE

Impact of drug particle shape on permeability and cellular uptake in the lung

(2019) S. Zellnitz et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Glottis motion effects on the particle transport and deposition in a subject-specific mouth-to-trachea model: A CFPD study

(2019) Jianan Zhao et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Computational analysis of deposition and translocation of inhaled nicotine and acrolein in the human body with e-cigarette puffing topographies

(2018) Ahmadreza Haghnegahdar et al.   AEROSOL SCIENCE AND TECHNOLOGY

Regional aerosol deposition in the human airways: The SimInhale benchmark case and a critical assessment of in silico methods

(2018) P. Koullapis et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

An in silico inter-subject variability study of extra-thoracic morphology effects on inhaled particle transport and deposition

(2018) Yu Feng et al.   JOURNAL OF AEROSOL SCIENCE

Experimental and DEM analyses on wheel-soil interaction

(2018) Mingjing Jiang et al.   JOURNAL OF TERRAMECHANICS

Use of computational fluid dynamics deposition modeling in respiratory drug delivery

(2018) P. Worth Longest et al.   Expert Opinion on Drug Delivery

Numerical investigation of the interaction, transport and deposition of multicomponent droplets in a simple mouth-throat model

(2017) Xiaole Chen et al.   JOURNAL OF AEROSOL SCIENCE

CFD-DEM study of the aerosolisation mechanism of carrier-based formulations with high drug loadings

(2017) Z.B. Tong et al.   POWDER TECHNOLOGY

Parameters and contact models for DEM simulations of agricultural granular materials: A review

(2016) Józef Horabik et al.   BIOSYSTEMS ENGINEERING

In VitroTests for Aerosol Deposition. IV: Simulating Variations in Human Breath Profiles for Realistic DPI Testing

(2016) Renishkumar R. Delvadia et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Computational transport, phase change and deposition analysis of inhaled multicomponent droplet–vapor mixtures in an idealized human upper lung model

(2016) Yu Feng et al.   JOURNAL OF AEROSOL SCIENCE

CFD–DEM investigation of the effect of agglomerate–agglomerate collision on dry powder aerosolisation

(2016) Zhenbo Tong et al.   JOURNAL OF AEROSOL SCIENCE

Regulatory Considerations for Approval of Generic Inhalation Drug Products in the US, EU, Brazil, China, and India

(2015) Sau L. Lee et al.   AAPS Journal

Numerical Modelling of Agglomeration and Deagglomeration in Dry Powder Inhalers: A Review

(2015) Jiecheng Yang et al.   CURRENT PHARMACEUTICAL DESIGN

Evaporation and condensation of multicomponent electronic cigarette droplets and conventional cigarette smoke particles in an idealized G3–G6 triple bifurcating unit

(2015) Y. Feng et al.   JOURNAL OF AEROSOL SCIENCE

Aerosolized drug delivery in patient-specific lung model during invasive high frequency oscillatory ventilation

(2015) Mohammed Alzahrany et al.   JOURNAL OF AEROSOL SCIENCE

Validating CFD Predictions of Pharmaceutical Aerosol Deposition with In Vivo Data

(2015) Geng Tian et al.   PHARMACEUTICAL RESEARCH

An Investigation into the Effect of Fine Lactose Particles on the Fluidization Behaviour and Aerosolization Performance of Carrier-Based Dry Powder Inhaler Formulations

(2014) Hanne Kinnunen et al.   AAPS PHARMSCITECH

Micron-particle transport, interactions and deposition in triple lung-airway bifurcations using a novel modeling approach

(2014) Y. Feng et al.   JOURNAL OF AEROSOL SCIENCE

Review of Adhesion Fundamentals for Micron-Scale Particles

(2014) Otis R. Walton   KONA Powder and Particle Journal

Evaluation and modification of commercial dry powder inhalers for the aerosolization of a submicrometer excipient enhanced growth (EEG) formulation

(2013) Yoen-Ju Son et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Model of the Deposition of Aerosol Particles in the Respiratory Tract of the Rat. II. Hygroscopic Particle Deposition

(2013) George A. Ferron et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Analysis of non-spherical particle transport in complex internal shear flows

(2013) Y. Feng et al.   PHYSICS OF FLUIDS

Vapor deposition during cigarette smoke inhalation in a subject-specific human airway model

(2012) Zhe Zhang et al.   JOURNAL OF AEROSOL SCIENCE

Laminar-to-turbulent fluid-nanoparticle dynamics simulations: Model comparisons and nanoparticle-deposition applications

(2011) Zhe Zhang et al.   International Journal for Numerical Methods in Biomedical Engineering

Energy dissipation in agglomerates during normal impact

(2011) Roberto Moreno-Atanasio   POWDER TECHNOLOGY

Mechanistic analysis and computer simulation of the aerodynamic dispersion of loose aggregates

(2010) Graham Calvert et al.   CHEMICAL ENGINEERING RESEARCH & DESIGN

Adhesion of Nanoparticles

(2010) Jan-Michael Y. Carrillo et al.   LANGMUIR

Targeted Drug-Aerosol Delivery in the Human Respiratory System

(2008) C. Kleinstreuer et al.   Annual Review of Biomedical Engineering