Human TRMT112-Methyltransferase Network Consists of Seven Partners Interacting with a Common Co-Factor

BUD23–TRMT112 interacts with the L protein of Borna disease virus and mediates the chromosomal tethering of viral ribonucleoproteins

(2021) Bea Clarise B. Garcia et al.   MICROBIOLOGY AND IMMUNOLOGY

THUMPD3–TRMT112 is a m2G methyltransferase working on a broad range of tRNA substrates

(2021) Wen-Qing Yang et al.   NUCLEIC ACIDS RESEARCH

Cardiac mitochondrial function depends on BUD23 mediated ribosome programming

(2020) Matthew Baxter et al.   eLife

The Gene Ontology resource: enriching a GOld mine

(2020) et al.   NUCLEIC ACIDS RESEARCH

Identification of recurrent fusion genes across multiple cancer types

(2019) Yan-Ping Yu et al.   Scientific Reports

KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells

(2019) Eric Metzger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112

(2019) Nhan van Tran et al.   NUCLEIC ACIDS RESEARCH

Human HemK2/KMT9/N6AMT1 is an active protein methyltransferase, but does not act on DNA in vitro, in the presence of Trm112

(2019) Clayton B. Woodcock et al.   Cell Discovery

Structural insight into human N6amt1–Trm112 complex functioning as a protein methyltransferase

(2019) Wenjing Li et al.   Cell Discovery

The Common Partner of Several Methyltransferases TRMT112 Regulates the Expression of N6AMT1 Isoforms in Mammalian Cells

(2019) Leetsi et al.   Biomolecules

Bi-allelic Variants in METTL5 Cause Autosomal-Recessive Intellectual Disability and Microcephaly

(2019) Elodie M. Richard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The ribosome: A hot spot for the identification of new types of protein methyltransferases

(2018) Steven G. Clarke   JOURNAL OF BIOLOGICAL CHEMISTRY

N 6 -Methyladenine DNA Modification in the Human Genome

(2018) Chuan-Le Xiao et al.   MOLECULAR CELL

Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes

(2018) Nhan van Tran et al.   NUCLEIC ACIDS RESEARCH

Activation mode of the eukaryotic m2G10tRNA methyltransferase Trm11 by its partner protein Trm112

(2016) Gabrielle Bourgeois et al.   NUCLEIC ACIDS RESEARCH

The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

(2015) Christiane Zorbas et al.   MOLECULAR BIOLOGY OF THE CELL

Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure

(2015) Juliette Létoquart et al.   NUCLEIC ACIDS RESEARCH

‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification

(2015) Sunny Sharma et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Stability of Ribosome Biogenesis Factor WBSCR22 Is Regulated by Interaction with TRMT112 via Ubiquitin-Proteasome Pathway

(2015) Kadri Õunap et al.   PLoS One

Novel Fusion Transcripts Associate with Progressive Prostate Cancer

(2014) Yan P. Yu et al.   AMERICAN JOURNAL OF PATHOLOGY

Structural and functional studies of Bud23–Trm112 reveal 18S rRNAN7-G1575 methylation occurs on late 40S precursor ribosomes

(2014) Juliette Létoquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WBSCR22/Merm1 is required for late nuclear pre-ribosomal RNA processing and mediates N7-methylation of G1639 in human 18S rRNA

(2014) Sara Haag et al.   RNA

The Human WBSCR22 Protein Is Involved in the Biogenesis of the 40S Ribosomal Subunits in Mammalian Cells

(2013) Kadri Õunap et al.   PLoS One

Trm112 Is Required for Bud23-Mediated Methylation of the 18S rRNA at Position G1575

(2012) S. Figaro et al.   MOLECULAR AND CELLULAR BIOLOGY

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

(2011) P. Gaudet et al.   BRIEFINGS IN BIOINFORMATICS

Mechanism of activation of methyltransferases involved in translation by the Trm112 ‘hub’ protein

(2011) Dominique Liger et al.   NUCLEIC ACIDS RESEARCH

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA

(2011) Erwin van den Born et al.   Nature Communications

Trm112p Is a 15-kDa Zinc Finger Protein Essential for the Activity of Two tRNA and One Protein Methyltransferases in Yeast

(2010) Marie-Hélène Mazauric et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncovering the Human Methyltransferasome

(2010) Tanya C. Petrossian et al.   MOLECULAR & CELLULAR PROTEOMICS

Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding

(2010) L. Songe-Moller et al.   MOLECULAR AND CELLULAR BIOLOGY

Deficiency in a Glutamine-Specific Methyltransferase for Release Factor Causes Mouse Embryonic Lethality

(2010) P. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Human AlkB Homolog ABH8 Is a tRNA Methyltransferase Required for Wobble Uridine Modification and DNA Damage Survival

(2010) D. Fu et al.   MOLECULAR AND CELLULAR BIOLOGY

The Arabidopsis SMO2, a homologue of yeast TRM112, modulates progression of cell division during organ growth

(2009) Zhubing Hu et al.   PLANT JOURNAL

HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1

(2008) Sabine Figaro et al.   FEBS LETTERS