4.7 Article

Hyaluronic acid/tannic acid hydrogel sunscreen with excellent anti-UV, antioxidant, and cooling effects

Journal

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 191, Issue -, Pages 918-924

Publisher

ELSEVIER
DOI: 10.1016/j.ijbiomac.2021.09.169

Keywords

Hyaluronic acid; Tannic acid; Hydrogel; Sunscreen; Cooling effect; Antioxidant activity

Funding

  1. Basic Science Research Program through the National Research Foundation of Korea (NRF) - Korean Government [NRF-2021R1A2B5B02002518]

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Excessive UV exposure can lead to skin damage, prompting increased use of sunscreens to protect the skin. Hydrogels, commonly used in cosmetics and medicines, have limitations in traditional sunscreen formulations. A novel HA/TA hydrogel sunscreen was developed with excellent UV protection, cooling effects, and potential applications.
Excessive exposure to UV radiation is one of the major factors that causes skin aging, erythema, burns, and skin cancer. Recently, the usage of sunscreens for skin protection has increased because the amount of UV radiation reaching the Earth's surface has increased owing to the destruction of the ozone layer that blocks UV radiation. Hydrogels with a three-dimensional network structure exhibit physical and chemical properties that are similar to those of the extracellular matrix in the human body, a high water content, flexibility, and biocompatibility. Therefore, they are applied in a wide range of fields, such as in cosmetics, medicines, and pharmaceuticals. However, conventional hydrogel-based sunscreens have drawbacks such as complicated process conditions, high cost, and low biocompatibility. In this study, a novel hydrogel-type sunscreen with excellent UV protection and cooling effects was prepared by a very simple process using two natural materials, hyaluronic acid (HA) and tannic acid (TA). The HA/TA hydrogels exhibited broad-spectrum UV protection in the UVA and UVB regions (280-360 nm). In addition, they showed excellent adhesion to the skin surface, antioxidative activity, cooling effect, and high moisture content, demonstrating great application potential as a hydrogel-type sunscreen.

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