HOXC6/8/10/13 predict poor prognosis and associate with immune infiltrations in glioblastoma

HoxC6 Functions as an Oncogene and Isoform HoxC6-2 May Play the Primary Role in Gastric Carcinogenesis

(2020) Jinping Lin et al.   DIGESTIVE DISEASES AND SCIENCES

Transcriptome analyses reveal molecular mechanisms underlying phenotypic differences among transcriptional subtypes of glioblastoma

(2020) Yuan‐Bo Pan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

(2020) Stephanie L. Guerra et al.   CANCER CELL

Molecular and clinical characterization of PARP9 in gliomas: A potential immunotherapeutic target

(2020) Hao Xu et al.   CNS Neuroscience & Therapeutics

Immunotherapy in Glioblastoma: Current Shortcomings and Future Perspectives

(2020) Bas Weenink et al.   Cancers

Management of glioblastoma: State of the art and future directions

(2020) Aaron C. Tan et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Linc00475 promotes the progression of glioma by regulating the miR‐141‐3p/YAP1 axis

(2020) Mingjun Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation

(2019) Liqun Yang et al.   Oncogenesis

Targeting APLN/APLNR improves anti-angiogenic efficiency and blunts pro-invasive side effects of VEGFA/VEGFR2-blockade in glioblastoma

(2019) Giorgia Mastrella et al.   CANCER RESEARCH

KCNQ1OT1 promotes autophagy by regulating miR‐200a/FOXO3/ATG7 pathway in cerebral ischemic stroke

(2019) Shijia Yu et al.   AGING CELL

Role of Apelin in Glioblastoma Vascularization and Invasion after Anti-VEGF Therapy: What Is the Impact on the Immune System?

(2019) Zohreh Amoozgar et al.   CANCER RESEARCH

Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma

(2019) PengYu Yang et al.   Cancer Management and Research

Current and Future Trends on Diagnosis and Prognosis of Glioblastoma: From Molecular Biology to Proteomics

(2019) Silantyev et al.   Cells

Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury

(2019) Andrew G. Masoud et al.   JOURNAL OF CLINICAL INVESTIGATION

Upregulation of microRNA-141 suppresses epithelial-mesenchymal transition and lymph node metastasis in laryngeal cancer through HOXC6-dependent TGF-β signaling pathway

(2019) Li Chen et al.   CELLULAR SIGNALLING

HOXC10 promotes proliferation and invasion and induces immunosuppressive gene expression in glioma

(2018) Shu Li et al.   FEBS Journal

Over-Expressed FEZF1 Predicts a Poor Prognosis in Glioma and Promotes Glioma Cell Malignant Biological Properties by Regulating Akt-ERK Pathway

(2018) Mingjun Yu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics

(2018) Eisuke Miyauchi et al.   PLoS One

MethSurv: a web tool to perform multivariable survival analysis using DNA methylation data

(2018) Vijayachitra Modhukur et al.   Epigenomics

HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis

(2018) TingDong Yan et al.   Nature Communications

HOXC8 promotes proliferation and migration through transcriptional up-regulation of TGFβ1 in non-small cell lung cancer

(2018) Houli Liu et al.   Oncogenesis

Abstract 3287: An integrated TCGA pan-cancer clinical data resource to drive high quality survival outcome analytics

(2018) Jianfang Liu et al.   CANCER RESEARCH

MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges

(2018) Alireza Mansouri et al.   NEURO-ONCOLOGY

HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells

(2018) Feng Zhang et al.   Cancer Cell International

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Identification of a panel of genes as a prognostic biomarker for glioblastoma

(2018) Fengfei Wang et al.   EBioMedicine

HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells

(2017) Mansi Shah et al.   Molecular Cancer

Toil enables reproducible, open source, big biomedical data analyses

(2017) John Vivian et al.   NATURE BIOTECHNOLOGY

Glioma epigenetics: From subclassification to novel treatment options

(2017) Olga Gusyatiner et al.   SEMINARS IN CANCER BIOLOGY

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

Deletions of 5′HOXCgenes are associated with lower extremity malformations, including clubfoot and vertical talus

(2016) David M Alvarado et al.   JOURNAL OF MEDICAL GENETICS

Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1

(2015) Fan Xuan et al.   NEURO-ONCOLOGY

Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer

(2014) Rafael Guerrero-Preston et al.   Epigenetics

TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours

(2013) Janet C. Lindsey et al.   ACTA NEUROPATHOLOGICA

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

DNA methylation profiles of long- and short-term glioblastoma survivors

(2013) Thoraia Shinawi et al.   Epigenetics

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study

(2013) Pedro Castelo-Branco et al.   LANCET ONCOLOGY

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Interaction of Developmental Transcription Factor HOXC11 with Steroid Receptor Coactivator SRC-1 Mediates Resistance to Endocrine Therapy in Breast Cancer

(2010) M. McIlroy et al.   CANCER RESEARCH

Differential Gene Expression in Benign Prostate Epithelium of Men with and without Prostate Cancer: Evidence for a Prostate Cancer Field Effect

(2010) M. C. Risk et al.   CLINICAL CANCER RESEARCH

HOXC8 Inhibits Androgen Receptor Signaling in Human Prostate Cancer Cells by Inhibiting SRC-3 Recruitment to Direct Androgen Target Genes

(2010) S. D. Axlund et al.   MOLECULAR CANCER RESEARCH

DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma

(2009) Lynda B. Bennett et al.   GENES CHROMOSOMES & CANCER

HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

(2009) Seok-Rae Park et al.   NATURE IMMUNOLOGY

DNA methylation inhibits p53-mediated survivin repression

(2009) N H Nabilsi et al.   ONCOGENE

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY