Complexities of the chemogenetic toolkit: Differential mDAAO activation by d-amino substrates and subcellular targeting

Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function

(2020) Valeriy V. Pak et al.   Cell Metabolism

Redox à la carte: Novel chemogenetic models of heart failure

(2020) Andrea Sorrentino et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential endothelial signaling responses elicited by chemogenetic H2O2 synthesis

(2020) Seyed Soheil Saeedi Saravi et al.   Redox Biology

pH-Lemon, a fluorescent protein-based pH reporter for acidic compartments

(2019) Sandra Burgstaller et al.   ACS Sensors

Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress

(2019) Andrea Sorrentino et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Slowly Reducible Genetically Encoded Green Fluorescent Indicator for In Vivo and Ex Vivo Visualization of Hydrogen Peroxide

(2019) Oksana M. Subach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Live cell imaging of signaling and metabolic activities

(2019) Maria R. Depaoli et al.   PHARMACOLOGY & THERAPEUTICS

Mitochondrial Carriers for Aspartate, Glutamate and Other Amino Acids: A Review

(2019) Magnus Monné et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods

(2019) Emrah Eroglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox biosensors in a context of multiparameter imaging

(2018) Alexander I. Kostyuk et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic biosensors for imaging nitric oxide in single cells

(2018) Emrah Eroglu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gene expression and activity of methionine converting enzymes in broiler chickens fed methionine isomers or precursors

(2018) Shuai Zhang et al.   POULTRY SCIENCE

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides

(2018) Olivier Sallin et al.   eLife

Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

(2018) Benjamin Steinhorn et al.   Nature Communications

Intact mitochondrial Ca 2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS)

(2017) Suphachai Charoensin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

(2017) Rongkun Tao et al.   NATURE METHODS

Real-time visualization of distinct nitric oxide generation of nitric oxide synthase isoforms in single cells

(2017) Emrah Eroglu et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells

(2017) Simon Burr et al.   NUCLEIC ACIDS RESEARCH

Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells

(2017) Emrah Eroglu et al.   Jove-Journal of Visualized Experiments

HyPer Family Probes: State of the Art

(2016) Dmitry S. Bilan et al.   ANTIOXIDANTS & REDOX SIGNALING

Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes

(2016) Bruce Morgan et al.   Nature Chemical Biology

Apollo-NADP+: a spectrally tunable family of genetically encoded sensors for NADP+

(2016) William D Cameron et al.   NATURE METHODS

Hydrogen Sulfide and Cellular Redox Homeostasis

(2016) Zhi-Zhong Xie et al.   Oxidative Medicine and Cellular Longevity

Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics

(2016) Emrah Eroglu et al.   Nature Communications

A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level

(2015) R. Erapaneedi et al.   EMBO JOURNAL

Generation of Red-Shifted Cameleons for Imaging Ca2+ Dynamics of the Endoplasmic Reticulum

(2015) Markus Waldeck-Weiermair et al.   SENSORS

A Highly Responsive and Selective Fluorescent Probe for Imaging Physiological Hydrogen Sulfide

(2014) Zhi-jie Chen et al.   BIOCHEMISTRY

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Response properties of the genetically encoded optical H2O2 sensor HyPer

(2014) Jonathan Weller et al.   FREE RADICAL BIOLOGY AND MEDICINE

Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide

(2014) Yulia G. Ermakova et al.   Nature Communications

Membrane transporters in a human genome-scale metabolic knowledgebase and their implications for disease

(2014) Swagatika Sahoo et al.   Frontiers in Physiology

How Much H2O2 Is Produced by Recombinant D-Amino Acid Oxidase in Mammalian Cells?

(2013) Mikhail E. Matlashov et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

(2013) Norihiro Shibuya et al.   Nature Communications

HyPer-3: A Genetically Encoded H2O2 Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging

(2012) Dmitry S. Bilan et al.   ACS Chemical Biology

Spatial and Temporal Analysis of NADPH Oxidase-Generated Hydrogen Peroxide Signals by Novel Fluorescent Reporter Proteins

(2012) Balázs Enyedi et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox compartmentalization and cellular stress

(2010) D. P. Jones et al.   DIABETES OBESITY & METABOLISM

d-Amino Acid Oxidase Generates Agonists of the Aryl Hydrocarbon Receptor fromd-Tryptophan

(2009) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Optimization of d-amino acid oxidase for low substrate concentrations - towards a cancer enzyme therapy

(2009) Elena Rosini et al.   FEBS Journal

Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases

(2009) Marcus Gutscher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-time imaging of the intracellular glutathione redox potential

(2008) Marcus Gutscher et al.   NATURE METHODS