Raptor is critical for increasing the mitochondrial proteome and skeletal muscle force during hypertrophy

Minimal mitochondrial respiration is required to prevent cell death by inhibition of mTOR signaling in CoQ-deficient cells

(2021) Ying Wang et al.   Cell Death Discovery

High-throughput proteomics fiber typing (ProFiT) for comprehensive characterization of single skeletal muscle fibers

(2020) Sebastian Kallabis et al.   Skeletal Muscle

Insulin/IGF1 signalling mediates the effects of β 2 ‐adrenergic agonist on muscle proteostasis and growth

(2019) Dawit A. Gonçalves et al.   Journal of Cachexia Sarcopenia and Muscle

Skeletal muscle mTORC1 regulates neuromuscular junction stability

(2019) Martina Baraldo et al.   Journal of Cachexia Sarcopenia and Muscle

Rapamycin-insensitive mechanistic target of rapamycin regulates basal and resistance exercise–induced muscle protein synthesis

(2018) Riki Ogasawara et al.   FASEB JOURNAL

Instant Clue: A Software Suite for Interactive Data Visualization and Analysis

(2018) Hendrik Nolte et al.   Scientific Reports

The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy

(2018) Jae-Sung You et al.   FASEB JOURNAL

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Comparative Analysis of Muscle Hypertrophy Models Reveals Divergent Gene Transcription Profiles and Points to Translational Regulation of Muscle Growth through Increased mTOR Signaling

(2017) Marcelo G. Pereira et al.   Frontiers in Physiology

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

S6K1 Is Required for Increasing Skeletal Muscle Force during Hypertrophy

(2016) Manuela Marabita et al.   Cell Reports

Muscle-specific GSK-3β ablation accelerates regeneration of disuse-atrophied skeletal muscle

(2015) Nicholas A.M. Pansters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Molecular mechanism regulating myosin and cardiac functions by ELC

(2014) Janine Lossie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

(2013) Masahiro Morita et al.   Cell Metabolism

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

(2013) S. A. Kang et al.   SCIENCE

1D and 2D annotation enrichment: a statistical method integrating quantitative proteomics with complementary high-throughput data

(2012) Juergen Cox et al.   BMC BIOINFORMATICS

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

Cardiac Raptor Ablation Impairs Adaptive Hypertrophy, Alters Metabolic Gene Expression, and Causes Heart Failure in Mice

(2011) Pankaj Shende et al.   CIRCULATION

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique

(2010) Craig A. Goodman et al.   FASEB JOURNAL

JunB transcription factor maintains skeletal muscle mass and promotes hypertrophy

(2010) Anna Raffaello et al.   JOURNAL OF CELL BIOLOGY

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

(2010) Denghong Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition

(2010) Calvin K. Yip et al.   MOLECULAR CELL

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activation

(2009) Bert Blaauw et al.   FASEB JOURNAL

Eccentric contractions lead to myofibrillar dysfunction in muscular dystrophy

(2009) Bert Blaauw et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner

(2008) I. Patursky-Polischuk et al.   MOLECULAR AND CELLULAR BIOLOGY

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA