Protective Effect of Xiao-Xu-Ming Decoction-Mediated Inhibition of ROS/NLRP3 Axis on Lipopolysaccharide-Induced Acute Lung Injury In Vitro and In Vivo

Astilbin protects against cerebral ischaemia/reperfusion injury by inhibiting cellular apoptosis and ROS-NLRP3 inflammasome axis activation

(2020) Yu Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Systems pharmacology reveals the mechanism of activity of Ge-Gen-Qin-Lian decoction against LPS-induced acute lung injury: A novel strategy for exploring active components and effective mechanism of TCM formulae

(2020) Zihe Ding et al.   PHARMACOLOGICAL RESEARCH

NLRC5 negatively regulates inflammatory responses in LPS-induced acute lung injury through NF-κB and p38 MAPK signal pathways

(2020) Yuanyuan Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction

(2020) Jinyao Jiang et al.   Redox Biology

The effects of cooking oil fumes-derived PM2.5 on blood vessel formation through ROS-mediated NLRP3 inflammasome pathway in human umbilical vein endothelial cells

(2019) Chaowei Shen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Ginsenoside Rb1 ameliorates Staphylococcus aureus-induced Acute Lung Injury through attenuating NF-κB and MAPK activation

(2019) Aftab Shaukat et al.   MICROBIAL PATHOGENESIS

Autoinflammatory disease in the lung

(2018) Thomas Scambler et al.   IMMUNOLOGY

NLRP3/ASC-mediated alveolar macrophage pyroptosis enhances HMGB1 secretion in acute lung injury induced by cardiopulmonary bypass

(2018) Lei Hou et al.   LABORATORY INVESTIGATION

Tight junction, mucin, and inflammasome-related molecules are differentially expressed in eosinophilic, mixed, and neutrophilic experimental asthma in mice

(2018) Hern-Tze Tina Tan et al.   ALLERGY

Acute Lung Injury: A Clinical and Molecular Review

(2016) Yasmeen Butt et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Incidence of Acute Respiratory Distress Syndrome—Reply

(2016) Giacomo Bellani et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

TLR4-Upregulated IL-1β and IL-1RI Promote Alveolar Macrophage Pyroptosis and Lung Inflammation through an Autocrine Mechanism

(2016) Xingying He et al.   Scientific Reports

Atrial natriuretic peptide down-regulates LPS/ATP-mediated IL-1β release by inhibiting NF-kB, NLRP3 inflammasome and caspase-1 activation in THP-1 cells

(2015) Letizia Mezzasoma et al.   IMMUNOLOGIC RESEARCH

Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats

(2015) Hongyu Zhao et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Rapid discovery and identification of 68 compounds in the active fraction from Xiao–Xu–Ming decoction (XXMD) by HPLC–HRMS and MTSF technique

(2014) Cai-Hong Wang et al.   CHINESE CHEMICAL LETTERS

Wogonoside Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice

(2014) Liang Zhang et al.   INFLAMMATION

Xiao-Xu-Ming decoction preserves mitochondrial integrity and reduces apoptosis after focal cerebral ischemia and reperfusion via the mitochondrial p53 pathway

(2013) Rui Lan et al.   JOURNAL OF ETHNOPHARMACOLOGY

TLR3-Triggered Reactive Oxygen Species Contribute to Inflammatory Responses by Activating Signal Transducer and Activator of Transcription-1

(2013) C.-S. Yang et al.   JOURNAL OF IMMUNOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Neuroprotective effects of Xiao-Xu-Ming decoction against ischemic neuronal injury in vivo and in vitro

(2009) Xin-Hong Zhu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Advances in Critical Care for the Nephrologist: Acute Lung Injury/ARDS

(2008) K. D. Liu et al.   Clinical Journal of the American Society of Nephrology