Fasted intestinal solubility limits and distributions applied to the biopharmaceutics and developability classification systems
Published 2021 View Full Article
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Title
Fasted intestinal solubility limits and distributions applied to the biopharmaceutics and developability classification systems
Authors
Keywords
Solubility, Fasted simulated intestinal fluid, Biopharmaceutics classification system, Developability classification system, Ibuprofen, Mefenamic acid, Griseofulvin, Dipyridamole, Furosemide, Paracetamol, Acyclovir
Journal
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
Volume 170, Issue -, Pages 160-169
Publisher
Elsevier BV
Online
2021-12-17
DOI
10.1016/j.ejpb.2021.12.006
References
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Related references
Note: Only part of the references are listed.- Small scale in vitro method to determine a bioequivalent equilibrium solubility range for fasted human intestinal fluid
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- Dual Level Statistical Investigation of Equilibrium Solubility in Simulated Fasted and Fed Intestinal Fluid
- (2017) Bayan E Ainousah et al. MOLECULAR PHARMACEUTICS
- Influence of Physiological Gastrointestinal Surfactant Ratio on the Equilibrium Solubility of BCS Class II Drugs Investigated Using a Four Component Mixture Design
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- Characterization of Human Duodenal Fluids in Fasted and Fed State Conditions
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- Statistical investigation of simulated intestinal fluid composition on the equilibrium solubility of biopharmaceutics classification system class II drugs
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- Analysis of Intra- and Intersubject Variability in Oral Drug Absorption in Human Bioequivalence Studies of 113 Generic Products
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- The Biopharmaceutics Classification System: Subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC
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- A review of drug solubility in human intestinal fluids: Implications for the prediction of oral absorption
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- Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs
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- The Developability Classification System: Application of Biopharmaceutics Concepts to Formulation Development
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