Physiological properties, composition and structural profiling of porcine gastrointestinal mucus

Comparing the permeability of human and porcine small intestinal mucus for particle transport studies

(2020) Lukasz Krupa et al.   Scientific Reports

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract

(2019) Matthew H. Foley et al.   PLoS Pathogens

Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis

(2019) Sjoerd van der Post et al.   GUT

Mucus and mucins in diseases of the intestinal and respiratory tracts

(2019) G. C. Hansson   JOURNAL OF INTERNAL MEDICINE

Modeling Barrier Properties of Intestinal Mucus Reinforced with IgG and Secretory IgA against Motile Bacteria

(2019) Feifei Xu et al.   ACS Infectious Diseases

Macro- and Microrheological Properties of Mucus Surrogates in Comparison to Native Intestinal and Pulmonary Mucus

(2019) Benedikt C. Huck et al.   BIOMACROMOLECULES

Permeability of the small intestinal mucus for physiologically relevant studies: Impact of mucus location and ex vivo treatment

(2019) Adam Macierzanka et al.   Scientific Reports

Predicting the viscosity of digesta from the physical characteristics of particle suspensions using existing rheological models

(2018) Allan K. Hardacre et al.   Journal of the Royal Society Interface

Mucin gel assembly is controlled by a collective action of non-mucin proteins, disulfide bridges, Ca2+-mediated links, and hydrogen bonding

(2018) Oliver W. Meldrum et al.   Scientific Reports

Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus

(2016) Harish Bokkasam et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

(2016) Joakim H. Bergström et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal and spatial expression of Muc2 and Muc5ac mucins during rat respiratory and digestive tracts development

(2016) V.A. Ferretti et al.   RESEARCH IN VETERINARY SCIENCE

The Use of Minipigs for Preclinical Safety Assessment by the Pharmaceutical Industry

(2016) Curtis Colleton et al.   TOXICOLOGIC PATHOLOGY

The immunology of the porcine skin and its value as a model for human skin

(2015) Artur Summerfield et al.   MOLECULAR IMMUNOLOGY

Relevance of dietary glycerophospholipids and sphingolipids to human health

(2015) P. Castro-Gómez et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Mucosal drug delivery: barriers, in vitro models and formulation strategies

(2015) M. Boegh et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

(2014) Marie Boegh et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins

(2013) Ana M. Rodríguez-Piñeiro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches

(2013) Anna Ermund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

DIGESTIVE PHYSIOLOGY OF THE PIG SYMPOSIUM: Intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways12

(2013) D. Burrin et al.   JOURNAL OF ANIMAL SCIENCE

The gastrointestinal mucus system in health and disease

(2013) Malin E. V. Johansson et al.   Nature Reviews Gastroenterology & Hepatology

Lamellar Structures of MUC2-Rich Mucin: A Potential Role in Governing the Barrier and Lubricating Functions of Intestinal Mucus

(2012) Andrew N. Round et al.   BIOMACROMOLECULES

Adsorption of bile salts to particles allows penetration of intestinal mucus

(2011) Adam Macierzanka et al.   Soft Matter

Biological hydrogels as selective diffusion barriers

(2011) Oliver Lieleg et al.   TRENDS IN CELL BIOLOGY

The pig: a model for human infectious diseases

(2011) François Meurens et al.   TRENDS IN MICROBIOLOGY

Insights into digestion and absorption of major nutrients in humans

(2010) Barbara E. Goodman   ADVANCES IN PHYSIOLOGY EDUCATION

Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products

(2010) Jan Willem van der Laan et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

The utility of the minipig as an animal model in regulatory toxicology

(2010) Gerd Bode et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Barrier properties of mucus

(2008) Richard A. Cone   ADVANCED DRUG DELIVERY REVIEWS

The porcine lung as a potential model for cystic fibrosis

(2008) Christopher S. Rogers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measurements of rat and mouse gastrointestinal pH, fluid and lymphoid tissue, and implications for in-vivo experiments

(2007) Emma L. McConnell et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY