Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects

Synthesis of sulpha drug based hydroxytriazene derivatives: Anti-diabetic, antioxidant, anti-inflammatory activity and their molecular docking studies

(2020) Poonam Sharma et al.   BIOORGANIC CHEMISTRY

Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase

(2020) Arturo L. Aguirre et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hybrid Quinoline-Sulfonamide Complexes (M2+) Derivatives with Antimicrobial Activity

(2020) Dumitrela Diaconu et al.   MOLECULES

The C7-aminomethylpyrrolidine group rescues the activity of a thio-fluoroquinolone

(2019) Sarah R.C. Lentz et al.   BIOCHIMIE

Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies

(2019) Arif Mermer et al.   BIOORGANIC CHEMISTRY

Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles

(2019) Ashraf Hassan et al.   MOLECULES

CLSI Methods Development and Standardization Working Group Best Practices for Evaluation of Antimicrobial Susceptibility Tests

(2018) Romney M. Humphries et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Quinolone-Triazole Hybrids and their Biological Activities

(2018) Jun-Hao Xu et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

New ciprofloxacin–dithiocarbamate–benzyl hybrids: design, synthesis, antibacterial evaluation, and molecular modeling studies

(2018) Ensieh Nasli Esfahani et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Fluoroquinolone-isatin hybrids and their biological activities

(2018) Zhi Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antibiotic resistance: a rundown of a global crisis

(2018) Bilal Aslam et al.   Infection and Drug Resistance

Structure of a quinolone-stabilized cleavage complex of topoisomerase IV fromKlebsiella pneumoniaeand comparison with a relatedStreptococcus pneumoniaecomplex

(2016) Dennis A. Veselkov et al.   Acta Crystallographica Section D-Structural Biology

Design, Synthesis, Antibacterial Evaluation and Docking Study of Novel 2-Hydroxy-3-(nitroimidazolyl)-propyl-derived Quinolone

(2014) Qing Li et al.   Chemical Biology & Drug Design

Improvement of antibacterial activity of some sulfa drugs through linkage to certain phthalazin-1(2H)-one scaffolds

(2014) Hany S. Ibrahim et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, molecular docking and antibacterial evaluation of various quinoline schiff bases: labeling and biodistribution of 99mTc-2-(p-hydroxybenzylidene)-1-(quinolin-4-yl) hydrazine

(2014) Reem I. Al-wabli et al.   MEDICINAL CHEMISTRY RESEARCH

Overcoming the current deadlock in antibiotic research

(2014) Till F. Schäberle et al.   TRENDS IN MICROBIOLOGY

Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities

(2013) Meltem Yolal Mentese et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and evaluation of clinafloxacin triazole hybrids as a new type of antibacterial and antifungal agents

(2012) Yan Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffold

(2012) Martin Krátký et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics

(2011) S. Alt et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

3-Chloro-N-(4-sulfamoylphenyl)propanamide

(2010) Mehmet Akkurt et al.   ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE

Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance

(2010) Varvara Pokrovskaya et al.   Expert Opinion on Drug Discovery

In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus

(2008) G. T. Robertson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and antibacterial activity of nitroaryl thiadiazole–gatifloxacin hybrids

(2008) Seyyedehsamira Jazayeri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Anticonvulsant Activity of Some Quinazolin-4-(3H)-one Derivatives

(2008) Hanan Georgey et al.   MOLECULES

Drug interactions modulate the potential for evolution of resistance

(2008) J.-B. Michel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA