Article
Nutrition & Dietetics
Catalina M. Mascaro, Cristina Bouzas, Josep A. Tur
Summary: This systematic review assesses the effect of Mediterranean lifestyle on the prevention and reversal of non-alcoholic fatty liver disease (NAFLD). The findings indicate that following a Mediterranean diet and engaging in regular physical activity is associated with improved clinical parameters and NAFLD/MetS. Therefore, adopting a Mediterranean lifestyle is an effective approach for the prevention and treatment of NAFLD.
Article
Medicine, Research & Experimental
Poliana C. Marinello, Paola S. Cella, Mayra T. J. Testa, Phillipe B. Guirro, Walison Augusto da Silva Brito, Camila S. Padilha, Alessandra L. Cecchini, Robin P. da Silva, Jose Alberto R. Duarte, Rafael Deminice
Summary: This study investigated the effects of creatine supplementation on the pathogenesis of non-alcoholic fatty liver disease and alcoholic liver disease. The results showed that creatine supplementation prevented high-fat diet-induced non-alcoholic fatty liver disease but exacerbated ethanol-induced alcoholic liver disease. The exacerbating effects may be related to oxidative stress and inflammation-mediated upregulation of ethanol metabolism.
Article
Behavioral Sciences
Christina Cordero, Elizabeth R. Pulgaron, Ashley N. Marchante-Hoffman, Maria M. Llabre, Krista M. Perreira, Daniela Sotres-Alvarez, Carmen R. Isasi, John P. Elder, Alan M. Delamater
Summary: This study analyzed the relationship between body image, social attitudes towards weight, and disordered eating behaviors among Hispanic youth. The results showed a strong association between body image and dieting and compensatory behaviors among adolescents, as well as between body image and overeating among children. However, significant associations were not observed with social attitudes towards weight.
Article
Biochemistry & Molecular Biology
Margalida Monserrat-Mesquida, Magdalena Quetglas-Llabres, Cristina Bouzas, Sofia Montemayor, Catalina M. Mascaro, Miguel Casares, Isabel Llompart, Lucia Ugarriza, J. Alfredo Martinez, Josep A. Tur, Antoni Sureda
Summary: A greater adherence to the Mediterranean diet is associated with greater improvements in intrahepatic fat content, cardiorespiratory fitness, and oxidative stress and inflammatory status in non-alcoholic fatty liver disease patients after a 6-month nutritional intervention based on the Mediterranean diet.
Review
Gastroenterology & Hepatology
Georg Semmler, Christian Datz, Michael Trauner
Summary: Nutrition and dietary interventions play a central role in the pathophysiology and management of NAFLD. Calorie restriction, adherence to a Mediterranean diet and intermittent fasting show promising effects in reducing liver fat content. Personalized dietary recommendations considering genetic background and microbiome could further enhance the effectiveness of interventions.
CLINICAL AND MOLECULAR HEPATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
U. Colon-Ramos, R. Monge-Rojas, V Smith-Castro, J. Wang, Y. Cheng, K. M. Perreira, L. Van Horn, D. Sotres-Alvarez, C. R. Isasi, L. C. Gallo
Summary: This study explored the mechanisms between family function, home environment, and eating behaviors among Hispanic youth, highlighting the impact of sociocultural context on their dietary habits. The findings suggest that acculturative stress, family dynamics, and household food security are significant factors influencing fruit and vegetable consumption and empty energy consumption among Hispanic youth. Confirmation of the directionality of these associations is needed through longitudinal data analysis.
PUBLIC HEALTH NUTRITION
(2021)
Article
Medicine, General & Internal
Maria Teresa Guagnano, Damiano D'Ardes, Rossi Ilaria, Francesca Santilli, Cosima Schiavone, Marco Bucci, Francesco Cipollone
Summary: Non-alcoholic fatty liver disease (NAFLD) is a common liver disease associated with weight, fat accumulation, and metabolic syndrome. Lifestyle changes can significantly improve NAFLD in patients. Ultrasonographic and elastosonographic techniques can help diagnose and monitor fatty liver disease, with liver size and stiffness correlated with various metabolic and fat-related variables.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Endocrinology & Metabolism
Li Rong, Junyan Zou, Wei Ran, Xiaohong Qi, Yaokai Chen, Hongjuan Cui, Jinjun Guo
Summary: Non-alcoholic fatty liver disease (NAFLD), now renamed as metabolic (dysfunction) associated with fatty liver disease (MAFLD), is a series of diseases characterized by excessive lipid deposition in the liver and often accompanied by obesity, diabetes, dyslipidemia, abnormal blood pressure, and other metabolic disorders. While changes in diet and lifestyle are recognized as non-drug treatment strategies, current drug therapies mainly target the pathogenic factors, key links of pathogenesis, and related metabolic disorders of NAFLD. There is still a lack of specific drugs, but treatments based on the enterohepatic axis, targeting gut microbiota, and new metabolism-regulating drugs are emerging.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Charu Arora, Anita Malhotra, Piyush Ranjan, Naval K. Vikram, S. N. Dwivedi, Namrata Singh, Shalimar, Vishwajeet Singh
Summary: Our study revealed significant variations in lifestyle among obese patients with NAFLD, including differences in diet quality and physical activity levels. The findings showed that few patients had both high-intensity exercise and good diet quality, emphasizing the importance of personalized adjustments in diet and physical activity.
FRONTIERS IN NUTRITION
(2021)
Article
Chemistry, Multidisciplinary
Renata B. Kostogrys, Magdalena Franczyk-Zarow, Edyta Kus, Kinga Topolska
Summary: This study analyzed the effects of a low-carbohydrate-high-protein diet on body weight, lipid metabolism, and kidney and liver function in rats. The results showed that this diet led to increased kidney weight, elevated serum cholesterol levels, increased liver fat content, and changes in fatty acid profile. Non-alcoholic fatty liver disease was observed in rats fed this diet.
APPLIED SCIENCES-BASEL
(2022)
Review
Biochemistry & Molecular Biology
Maria Notarnicola, Alberto Ruben Osella, Maria Gabriella Caruso, Pasqua Letizia Pesole, Antonio Lippolis, Valeria Tutino, Caterina Bonfiglio, Valentina De Nunzio, Maria Principia Scavo, Antonella Mirizzi, Isabella Franco, Tamara Lippolis, Rosalba D'Alessandro, Maria Grazia Refolo, Caterina Messa
Summary: NAFLD is considered as a hepatic manifestation of metabolic syndrome, characterized by excessive lipid accumulation and oxidative stress leading to liver injury. The identification of genetic and epigenetic modifications contributing to NAFLD pathogenesis is crucial, while lifestyle modifications remain the main prevention and treatment approach.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nutrition & Dietetics
Jack Feehan, Alexandra Mack, Caroline Tuck, Jorge Tchongue, Darcy Q. Holt, William Sievert, Gregory T. Moore, Barbora de Courten, Alexander Hodge
Summary: Time-restricted fasting (TRF) for 16 hours daily without calorie restrictions was found to be more effective than standard care (SC) in improving visceral adiposity and steatosis in patients with non-alcoholic fatty liver disease (NAFLD).
Article
Public, Environmental & Occupational Health
Esmeralda Castro, Nichole R. Kelly, Elizabeth L. Budd
Summary: Hispanic/Latino adults in the U.S. are more likely to develop diet-related chronic diseases. While healthcare provider recommendations have been effective in promoting health behavior change, there is limited information about healthy eating recommendations specifically for Hispanics/Latinos. This study aimed to investigate the prevalence and adherence to healthcare provider-delivered healthy eating recommendations among a sample of Hispanic/Latino adults.
PREVENTIVE MEDICINE REPORTS
(2023)
Article
Nutrition & Dietetics
Gabriele Castelnuovo, Nuria Perez-Diaz-del-Campo, Chiara Rosso, Marta Guariglia, Angelo Armandi, Aurora Nicolosi, Gian Paolo Caviglia, Elisabetta Bugianesi
Summary: This study found that late chronotype and low adherence to the Mediterranean diet were associated with an increased risk of liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD).
Article
Nutrition & Dietetics
Shunming Zhang, Yeqing Gu, Shanshan Bian, Magdalena J. Gorska, Qing Zhang, Li Liu, Ge Meng, Zhanxin Yao, Hongmei Wu, Yawen Wang, Tingjing Zhang, Xuena Wang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Lu Qi, Kaijun Niu
Summary: The study found that dietary patterns rich in animal foods or sugar were associated with a higher risk of NAFLD among Chinese adults, whereas a vegetable-rich dietary pattern was not associated.
CLINICAL NUTRITION
(2021)
Article
Public, Environmental & Occupational Health
Natalia I. Heredia, Tianlin Xu, MinJae Lee, Lorna H. McNeill, Belinda M. Reininger
Summary: The study found significant associations between neighborhood environment and mental health, physical activity, and CRP levels in Hispanic/Latino adults on the Texas-Mexico border, although the estimates were small. The neighborhood environment is a meaningful factor to consider for health interventions in this population, but further research on the magnitude of the associations is needed.
AMERICAN JOURNAL OF HEALTH PROMOTION
(2022)
Article
Oncology
Ming Guo, Abha Khanna, Agata A. Tinnirello, Jessica Hwang, Ping Zhang, Li Xu, Guojun Li, Kristina R. Dahlstrom, Erich M. Sturgis, John Stewart
Summary: This study evaluated the accuracy of the Cobas human papillomavirus (HPV) assay for detecting high-risk HPV and HPV-16 in head and neck fine-needle aspiration (FNA) specimens with squamous cell carcinoma. The results showed that the Cobas HPV assay had high accuracy in determining HPV status in FNA specimens and that FNA needle rinse was valid for Cobas HPV testing.
CANCER CYTOPATHOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Natalia Heredia, Xiaotao Zhang, Maya Balakrishnan, Carrie R. Daniel, Jessica P. Hwang, Lorna H. McNeill, Aaron P. Thrift
Summary: Healthy eating and physical activity are associated with reduced odds of NAFLD, with physical activity having a more significant impact on reducing the risk of advanced fibrosis. These behaviors should be targeted in public health interventions.
PREVENTIVE MEDICINE
(2022)
Letter
Infectious Diseases
Joseph T. Klingen, Khalis Mustafayev, Marcel Yibirin, Jessica P. Hwang, Harrys A. Torres
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2023)
Letter
Gastroenterology & Hepatology
Chia-Yu Chiu, Krina Patel, Sheeba K. Thomas, Fareed Khawaja, Natalie J. M. Dailey Garnes, Hans C. Lee, Maro Ohanian, Ying Jiang, Lan S. Wang, Jessica P. Hwang, Harrys A. Torres
HEPATOLOGY INTERNATIONAL
(2023)
Article
Oncology
Jessica P. Hwang, Kathryn B. Arnold, Joseph M. Unger, Rashmi Chugh, Monica A. Tincopa, Rohit Loomba, Dawn Hershman, Scott D. Ramsey
Summary: This study investigated the adherence to practice guidelines in patients with HBV, HCV, or HIV receiving anticancer treatment. It was found that many patients did not receive guideline-recommended antiviral treatment, indicating a need for further education to improve adherence to guidelines.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Joseph M. Unger, Cathee Till, Jessica P. Hwang, Kathryn B. Arnold, Michael Leblanc, Dawn L. Hershman, Scott D. Ramsey
Summary: Researchers have identified a risk model with 7 factors and constructed a risk score with 4 levels to predict the presence of viral infection in cancer patients. Using this model, individuals in the highest risk group were 18 times more likely to be viral positive compared to those with no risk factors. A risk-stratified screening approach using this limited set of questions could be an effective strategy to streamline screening for viral infection.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Nutrition & Dietetics
Natalia I. Heredia, Aaron P. Thrift, David J. Ramsey, Rohit Loomba, Hashem B. El-Serag
Summary: This study found that adopting a Mediterranean-style diet is significantly associated with a lower risk of MAFLD in Veterans, especially when controlling for weight and energy intake.
Article
Oncology
Maria A. Lopez-Olivo, Gabrielle F. Duhon, Juan I. Ruiz, Mehmet Altan, Hussein Tawbi, Adi Diab, Clifton O. Bingham, Cassandra Calabrese, Natalia I. Heredia, Robert J. Volk, Maria E. Suarez-Almazor
Summary: Through interviews with 20 experienced oncologists and non-oncology specialists, this study identified the information considered most useful by physicians when discussing treatment initiation with immune checkpoint inhibitors (ICIs) in cancer patients with pre-existing autoimmune disease. The key information includes the benefits of ICIs, the probability of immune-related adverse events (irAEs), and the risks of underlying autoimmune condition flares associated with the use of ICIs.
Article
Public, Environmental & Occupational Health
William B. B. Perkison, Serena A. A. Rodriguez, Fernanda Velasco-Huerta, Patenne D. D. Mathews, Catherine Pulicken, Sidra S. S. Beg, Natalia I. I. Heredia, Pierre Fwelo, Grace E. E. White, Belinda M. M. Reininger, John W. W. McWhorter, Roshanda Chenier, Maria E. E. Fernandez
Summary: Diabetes is a prevalent and preventable chronic health condition in the United States. The National Diabetes Prevention Program (National DPP) is an evidence-based program designed to reduce diabetes risk through intensive group counseling. However, there are barriers to the implementation of the program, including limited awareness, lack of clinical processes, and limited reimbursement incentives.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Natalia I. Heredia, Qiong Dong, Shine Chang, Lorna H. McNeill
Summary: This study revealed that current alcohol use and high physical activity were associated with lower BMIs in Mexican-origin adults, but there was no significant interaction between physical activity and alcohol use on BMI.
JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES
(2022)