Updating the use of biochemical biomarkers in fish for the evaluation of alterations produced by pharmaceutical products

Enzymatic activity changes in striped catfish Pseudoplatystoma magdaleniatum, induced by exposure to different concentrations of ibuprofen and triclosan

(2021) Sara E. Gallego R et al.   CHEMOSPHERE

Zebrafish as a Screening Model to Study the Single and Joint Effects of Antibiotics

(2021) Roxana Jijie et al.   Pharmaceuticals

Response of aquatic macroinvertebrates communities to multiple anthropogenic stressors in a lowland tributary river

(2021) Stefan-Adrian Strungaru et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Lethal and Sub-lethal Effects of Nitrofurantoin on Zebrafish Early-Life Stages

(2020) Reginaldo Carlyle Silva de Oliveira et al.   WATER AIR AND SOIL POLLUTION

Toxic effects of environmentally realistic concentrations of diclofenac in organisms from two distinct trophic levels, Hediste diversicolor and Solea senegalensis

(2020) Bruno Nunes et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Embryotoxicity of atrazine and its degradation products to early life stages of zebrafish (Danio rerio)

(2020) Jana Blahova et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Molecular cloning, mRNA expression and functional characterization of a catalase from Chinese black sleeper (Bostrychus sinensis)

(2020) Bin Shen et al.   FISH & SHELLFISH IMMUNOLOGY

Glutathione-S-transferase alpha-4 in Hippocampus abdominalis (big-belly seahorse): Molecular characterization, antioxidant properties, and its potent immune response

(2020) Kishanthini Nadarajapillai et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Acute effects of neonicotinoid insecticides on Mytilus galloprovincialis: A case study with the active compound thiacloprid and the commercial formulation calypso 480 SC

(2020) Alzbeta Stara et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Molecular and functional characterization of a mitochondrial glutathione reductase homolog from redlip mullet (Liza haematocheila): Disclosing its antioxidant properties in the fish immune response mechanism

(2020) J.C. Harasgama et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Physiological and metabolic approach of plastic additive effects: Immune cells responses

(2020) Mario Alberto Burgos-Aceves et al.   JOURNAL OF HAZARDOUS MATERIALS

Can dietary ginger (Zingiber officinale) alter biochemical and immunological parameters and gene expression related to growth, immunity and antioxidant system in zebrafish (Danio rerio)?

(2019) Ehsan Ahmadifar et al.   AQUACULTURE

Long-term effects of oxytetracycline exposure in zebrafish: A multi-level perspective

(2019) Ana Rita Almeida et al.   CHEMOSPHERE

Exposure to dilute concentrations of bupropion affects zebrafish early life stages

(2019) Mariana Bernardes Franco et al.   CHEMOSPHERE

Biological Characteristics, Growth Parameters and Mortality Rate of Carassius auratus in the Shadegan Wetland (Iran)

(2019) Seyed Ahmad Reza Hashemi et al.   International Journal of Environmental Research

Biomarker and behavioural responses of an estuarine fish following acute exposure to fluoxetine

(2019) Irina A. Duarte et al.   MARINE ENVIRONMENTAL RESEARCH

Embryonic development, locomotor behavior, biochemical, and epigenetic effects of the pharmaceutical drugs paracetamol and ciprofloxacin in larvae and embryos of Danio rerio when exposed to environmental realistic levels of both drugs

(2019) Ana F. Nogueira et al.   ENVIRONMENTAL TOXICOLOGY

The use of zebrafish (Danio rerio) as biomedical models

(2019) Tsegay Teame et al.   Animal Frontiers

Integrated biomarker response index to assess toxic effects of environmentally relevant concentrations of paracetamol in a neotropical catfish (Rhamdia quelen)

(2019) Maiara C. Perussolo et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Dietary influences of oxytetracycline on the growth and serum biomarkers of Oreochromis niloticus (L.)

(2019) Roy Beryl Julinta et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Presence of pharmaceutical compounds, levels of biochemical biomarkers in seafood tissues and risk assessment for human health: Results from a case study in North-Western Spain

(2019) Salomé Martínez-Morcillo et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Occurrence, interactive effects and ecological risk of diclofenac in environmental compartments and biota - a review

(2019) Palanivel Sathishkumar et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Ibuprofen at environmentally relevant concentrations alters embryonic development, induces teratogenesis and oxidative stress in Cyprinus carpio

(2019) Verónica Margarita Gutiérrez-Noya et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Neurotoxic and respiratory effects of human use drugs on a Neotropical fish species, Phalloceros harpagos

(2019) Paula Rodrigues de Oliveira dos Santos et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Antioxidant status, biochemical, and hematological responses in a cultivable fish Cirrhinus mrigala exposed to an aquaculture antibiotic Sulfamethazine

(2018) Mathan Ramesh et al.   AQUACULTURE

A multibiomarker approach highlights effects induced by the human pharmaceutical gemfibrozil to gilthead seabream Sparus aurata

(2018) A. Barreto et al.   AQUATIC TOXICOLOGY

Effect of human pharmaceuticals common to aquatic environments on hepatic CYP1A and CYP3A-like activities in rainbow trout ( Oncorhynchus mykiss ): An in vitro study

(2018) Viktoriia Burkina et al.   CHEMOSPHERE

Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish ( Danio rerio ) embryos

(2018) Luís M. Félix et al.   CHEMOSPHERE

Oxidative stress and antioxidant enzyme defence system in seminal plasma of common carp (Cyprinus carpio) and rainbow trout (Oncorhynchus mykiss) during spawning season

(2018) A. Shaliutina-Kolešová et al.   CZECH JOURNAL OF ANIMAL SCIENCE

Stereoselective effects of ibuprofen in adult zebrafish ( Danio rerio ) using UPLC-TOF/MS-based metabolomics

(2018) Yue Song et al.   ENVIRONMENTAL POLLUTION

Assessment of biochemical alterations in the neotropical fish species Phalloceros harpagos after acute and chronic exposure to the drugs paracetamol and propranolol

(2018) Beatriz V. R. Pereira et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effects of glyphosate on early life stages: comparison between Cyprinus carpio and Danio rerio

(2018) Emma Fiorino et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effect of nitrite exposure on the antioxidant enzymes and glutathione system in the liver of bighead carp, Aristichthys nobilis

(2018) Yan Lin et al.   FISH & SHELLFISH IMMUNOLOGY

Biochemical responses of Solea senegalensis after continuous flow exposure to urban effluents

(2018) B. Díaz-Garduño et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Biomarker response, health indicators, and intestinal microbiome composition in wild brown trout ( Salmo trutta m. fario L.) exposed to a sewage treatment plant effluent-dominated stream

(2018) Pham Thai Giang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The effects of sewage treatment plant effluents on hepatic and intestinal biomarkers in common carp ( Cyprinus carpio )

(2018) Sidika Sakalli et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effects of waterborne antidepressants on non-target animals living in the aquatic environment: A review

(2018) Pavla Sehonova et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Oxytetracycline effects in specific biochemical pathways of detoxification, neurotransmission and energy production in Oncorhynchus mykiss

(2018) S. Rodrigues et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Chronic effects of carbamazepine on zebrafish: Behavioral, reproductive and biochemical endpoints

(2018) Niedja da Silva Santos et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Glutathione peroxidase and glutathione S-transferase in blood and liver from a hypoxia-tolerant fish under oxygen deprivation

(2018) C. Rocha-Santos et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effects of waterborne exposure to the antidepressant fluoxetine on swimming, shoaling and anxiety behaviours of the mosquitofish Gambusia holbrooki

(2018) Fernando J. Meijide et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Ecotoxicological evaluation of gilthead seabream (Sparus aurata) exposed to the antibiotic oxytetracycline using a multibiomarker approach

(2018) S. Rodrigues et al.   MARINE ENVIRONMENTAL RESEARCH

Exposure to low concentration of fluoxetine affects development, behaviour and acetylcholinesterase activity of zebrafish embryos

(2018) Natália Oliveira de Farias et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Biomonitoring, physico-chemical, and biomarker evaluations of abattoir effluent discharges into the Ogun River from Kara Market, Ogun State, Nigeria, using Clarias gariepinus

(2018) Esther I. Olaniran et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Opinion paper about organic trace pollutants in wastewater: Toxicity assessment in a European perspective

(2018) Roberta Pedrazzani et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Living in a multi-stressors environment: An integrated biomarker approach to assess the ecotoxicological response of meagre (Argyrosomus regius) to venlafaxine, warming and acidification

(2018) Ana Luísa Maulvault et al.   ENVIRONMENTAL RESEARCH

mRNA expression of antioxidant and biotransformation enzymes in zebrafish (Danio rerio) embryos after exposure to the tricyclic antidepressant amitriptyline

(2018) Pavla Sehonova et al.   CHEMOSPHERE

Integrated assessment of sediment contaminant levels and biological responses in sentinel fish species Atherinella brasiliensis from a sub-tropical estuary in south Atlantic

(2018) Lilian Dalago Salgado et al.   CHEMOSPHERE

Assessment of toxic effects of the antibiotic erythromycin on the marine fish gilthead seabream (Sparus aurata L.) by a multi-biomarker approach

(2018) Sara Rodrigues et al.   CHEMOSPHERE

Effects of Multi-Component Mixtures from Sewage Treatment Plant Effluent on Common Carp (Cyprinus carpio) under Fully Realistic Condition

(2017) Pham Thai Giang et al.   ENVIRONMENTAL MANAGEMENT

Molecular identification and functional delineation of a glutathione reductase homolog from disk abalone ( Haliotis discus discus ): Insights as a potent player in host antioxidant defense

(2017) H.M.L.P.B. Herath et al.   FISH & SHELLFISH IMMUNOLOGY

Joint toxicity of fluoroquinolone and tetracycline antibiotics to zebrafish (Danio rerio) based on biochemical biomarkers and histopathological observation

(2017) Lihe Ding et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Occurrence of personal care products as emerging chemicals of concern in water resources: A review

(2017) Diana Montes-Grajales et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effects of the pharmaceutical contaminants ibuprofen, diclofenac, and carbamazepine alone, and in combination, on oxidative stress parameters in early life stages of tench (Tinca tinca)

(2017) V. Stancova et al.   VETERINARNI MEDICINA

Effects of azithromycin on tilapia (Oreochromis niloticus ): health status evaluation using biochemical, physiological and morphological biomarkers

(2016) Natália Sayuri Shiogiri et al.   AQUACULTURE RESEARCH

Bioconcentration, metabolism, and biomarker responses in marine medaka (Oryzias melastigma) exposed to sulfamethazine

(2016) Songhe Zhao et al.   AQUATIC TOXICOLOGY

Temperature rise and microplastics interact with the toxicity of the antibiotic cefalexin to juveniles of the common goby ( Pomatoschistus microps ): Post-exposure predatory behaviour, acetylcholinesterase activity and lipid peroxidation

(2016) Elsa Fonte et al.   AQUATIC TOXICOLOGY

Effects of Dietary Exposure to Sulfamethazine on the Hematological Parameters and Hepatic Oxidative Stress Biomarkers in Nile Tilapia (Oreochromis niloticus)

(2016) Fernanda Garcia Sampaio et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Endocrine disrupting effects of domestic wastewater on reproduction, sexual behavior, and gene expression in the brackish medaka Oryzias melastigma

(2016) Te-Hao Chen et al.   CHEMOSPHERE

The effects of the painkiller diclofenac and hypoxia on gene transcription and antioxidant system in the gills of three-spined stickleback

(2016) Pedro Lubiana et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Multilevel assessment of ivermectin effects using different zebrafish life stages

(2016) Rhaul Oliveira et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Rainbow trout (Oncorhynchus mykiss) pro-oxidant and genotoxic responses following acute and chronic exposure to the antibiotic oxytetracycline

(2016) Sara Rodrigues et al.   ECOTOXICOLOGY

Drugs of environmental concern modify Solea senegalensis physiology and biochemistry in a temperature-dependent manner

(2016) A González-Mira et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The use of juvenile Solea solea as sentinel in the marine platform of the Ebre Delta: in vitro interaction of emerging contaminants with the liver detoxification system

(2016) Marina Crespo et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The effects of ciprofloxacin on early life stages of common carp (Cyprinus carpio)

(2016) Dana Zivna et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Assessment of pharmaceutical and personal care products (PPCPs) of Dalong Lake in Xuzhou by concentration monitoring and bio-effects monitoring process

(2016) Haijing Yu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Assessment of Detoxifying Markers for Florfenicol in Rainbow Trout Liver

(2016) Antonia Concetta Elia et al.   JOURNAL OF AQUATIC ANIMAL HEALTH

An in vitro screening with emerging contaminants reveals inhibition of carboxylesterase activity in aquatic organisms

(2015) Montserrat Solé et al.   AQUATIC TOXICOLOGY

Evaluation of Biochemical, Genetic and Hematological Biomarkers in a Commercial Catfish Rhamdia quelen Exposed to Diclofenac

(2015) Ariane Ghelfi et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Ecological risk assessment of the antibiotic enrofloxacin applied to Pangasius catfish farms in the Mekong Delta, Vietnam

(2015) Margot Andrieu et al.   CHEMOSPHERE

Effects of the pharmaceuticals diclofenac and metoprolol on gene expression levels of enzymes of biotransformation, excretion pathways and estrogenicity in primary hepatocytes of Nile tilapia (Oreochromis niloticus)

(2015) Frederike Gröner et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Responses of the hepatic glutathione antioxidant defense system and related gene expression in juvenile common carp after chronic treatment with tributyltin

(2015) Zhi-Hua Li et al.   ECOTOXICOLOGY

Effects of norfloxacin on hepatic genes expression of P450 isoforms (CYP1A and CYP3A), GST and P-glycoprotein (P-gp) in Swordtail fish (Xiphophorus Helleri)

(2015) Ximei Liang et al.   ECOTOXICOLOGY

Chronic exposures to low and high concentrations of ibuprofen elicit different gene response patterns in a euryhaline fish

(2015) Ken M. Jeffries et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Chronic exposure to pollutants in Madín Reservoir (Mexico) alters oxidative stress status and flesh quality in the common carp Cyprinus carpio

(2015) Gabriela Morachis-Valdez et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effect of excessive doses of oxytetracycline on stress-related biomarker expression in coho salmon

(2015) Toshiki Nakano et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Biochemical effects of the pharmaceutical drug paracetamol on Anguilla anguilla

(2015) Bruno Nunes et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Assessment of biomarkers for contaminants of emerging concern on aquatic organisms downstream of a municipal wastewater discharge

(2015) Edyta J. Jasinska et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A review of what is an emerging contaminant

(2014) Sébastien Sauvé et al.   Chemistry Central Journal

Biochemical effects of glyphosate based herbicide, Excel Mera 71 on enzyme activities of acetylcholinesterase (AChE), lipid peroxidation (LPO), catalase (CAT), glutathione-S-transferase (GST) and protein content on teleostean fishes

(2014) Palas Samanta et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

A multi-biomarker assessment of single and combined effects of norfloxacin and sulfamethoxazole on male goldfish (Carassius auratus)

(2014) Jianchao Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effects of selected xenobiotics on hepatic and plasmatic biomarkers in juveniles of Solea senegalensis

(2014) Montserrat Solé et al.   ENVIRONMENTAL RESEARCH

In Vitro Interaction of Emerging Contaminants with the Cytochrome P450 System of Mediterranean Deep-Sea Fish

(2014) Carla Ribalta et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors

(2014) N. Creusot et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effects of heavy metals (Cd, Cu, Cr, Pb, Zn) on fish glutathione metabolism

(2014) A. Eroglu et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

A novel murrel Channa striatus mitochondrial manganese superoxide dismutase: gene silencing, SOD activity, superoxide anion production and expression

(2014) Jesu Arockiaraj et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus)

(2014) Jianchao Liu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Detrimental Effects of Metronidazole on the Liver of Freshwater Common Carp (Cyprinus carpio L.)

(2013) Junyan Han et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Bioconcentration, metabolism, and biomarker responses in freshwater fish Carassius auratus exposed to roxithromycin

(2013) Jianchao Liu et al.   CHEMOSPHERE

Glutathione and its dependent enzymes’ modulatory responses to toxic metals and metalloids in fish—a review

(2013) K. Srikanth et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effects of oxytetracycline and amoxicillin on development and biomarkers activities of zebrafish (Danio rerio)

(2013) Rhaul Oliveira et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Toxicological Effects of the Antibiotic Oxytetracycline to an Indian Major Carp Labeo rohita

(2012) T. R. Ambili et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Contamination by metals and pharmaceuticals in northern Taihu Lake (China) and its relation to integrated biomarker response in fish

(2012) Guanghua Lu et al.   ECOTOXICOLOGY

Effects of Ibuprofen on hematological, biochemical and enzymological parameters of blood in an Indian major carp, Cirrhinus mrigala

(2012) M. Saravanan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The effects of diclofenac on early life stages of common carp (Cyprinus carpio)

(2012) Stanislava Stepanova et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Consumption and occurrence of pharmaceutical and personal care products in the aquatic environment in Spain

(2012) Sheyla Ortiz de García et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Spatial and seasonal variations of pharmaceuticals and endocrine disruptors in the Atibaia River, São Paulo State (Brazil)

(2011) Cassiana C. Montagner et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Effect of human pharmaceutical Carbamazepine on the quality parameters and oxidative stress in common carp (Cyprinus carpio L.) spermatozoa

(2010) Zhi-Hua Li et al.   CHEMOSPHERE

17β estradiol induced ROS generation, DNA damage and enzymatic responses in the hepatic tissue of Japanese sea bass

(2010) Harikrishnan Thilagam et al.   ECOTOXICOLOGY

Enzymatic alterations and RNA/DNA ratio in intestine of rainbow trout, Oncorhynchus mykiss, induced by chronic exposure to carbamazepine

(2010) Zhi-Hua Li et al.   ECOTOXICOLOGY

Acute toxicity of carbamazepine to juvenile rainbow trout (Oncorhynchus mykiss): Effects on antioxidant responses, hematological parameters and hepatic EROD

(2010) Zhi-Hua Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Impacts of emerging organic contaminants on freshwater resources: Review of recent occurrences, sources, fate and effects

(2010) Amrita Pal et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Modulation of antioxidant defence system in brain of rainbow trout (Oncorhynchus mykiss) after chronic carbamazepine treatment

(2009) Zhi-Hua Li et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Comparative study of superoxide dismutase and glutathione peroxidase activity in embryos and skeletal muscles of adult fish

(2008) A. R. Isuev et al.   BIOLOGY BULLETIN

Hepatic and branchial glutathione S-transferases of two fish species: Substrate specificity and biotransformation of microcystin-LR

(2008) I. Šetlíková et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Content of cysteine, reduced and oxidized glutathione in spermatozoa of representatives ofAcipenseriformes(Acipenser baeriiandA. ruthenus) as well as teleosts (Perca fluviatilisandSander lucioperca)

(2008) K. Stejskal et al.   JOURNAL OF APPLIED ICHTHYOLOGY