Biogenesis of secretory immunoglobulin M requires intermediate non‐native disulfide bonds and engagement of the protein disulfide isomerase ERp44

A Virtuous Cycle Operated by ERp44 and ERGIC-53 Guarantees Proteostasis in the Early Secretory Compartment

(2021) Tiziana Tempio et al.   iScience

Structural insights into immunoglobulin M

(2020) Yaxin Li et al.   SCIENCE

Zinc regulates ERp44-dependent protein quality control in the early secretory pathway

(2019) Satoshi Watanabe et al.   Nature Communications

The IgM pentamer is an asymmetric pentagon with an open groove that binds the AIM protein

(2018) Emiri Hiramoto et al.   Science Advances

Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER–Golgi interface

(2017) Satoshi Watanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A peptide extension dictates IgM assembly

(2017) Dzana Pasalic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of N-glycans in the polymerization-dependent aggregation of mutant Ig-μ chains in the early secretory pathway

(2017) Chiara Giannone et al.   Scientific Reports

Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention

(2016) Kai Yang et al.   STRUCTURE

Progressive quality control of secretory proteins in the early secretory compartment by ERp44

(2014) S. Sannino et al.   JOURNAL OF CELL SCIENCE

ERdj5 Is the ER Reductase that Catalyzes the Removal of Non-Native Disulfides and Correct Folding of the LDL Receptor

(2013) Ojore Benedict Valentine Oka et al.   MOLECULAR CELL

High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation

(2013) R. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Many Roles of the Bacterial Envelope Reducing Pathways

(2012) Seung-Hyun Cho et al.   ANTIOXIDANTS & REDOX SIGNALING

ERp44 and ERGIC-53 Synergize in Coupling Efficiency and Fidelity of IgM Polymerization and Secretion

(2010) Margherita Cortini et al.   TRAFFIC

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

(2009) D. M. Czajkowsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA