The regulatory roles of dietary fibers on host health via gut microbiota-derived short chain fatty acids

As a component of nutraceuticals, dietary fibers (DFs) are essential for maintain human growth and health via the regulation of gut microbiota in the digestive tract. In this review, we summarize food-derived DFs and their effect on gut microbiota-derived short-chain fatty acids (SCFAs). DFs accelerate the production of SCFAs mainly by stimulating intestinal Lactobacillus, Bifidobacterium and Akkermansia to treat diabetes, obesity, cancer, inflammation and immunodeficiency. Further studies should focus on clarifying the detailed mechanism between DFs and diseases associated with gut microbiota-mediated SCFAs.

Automated summary

Dietary fibers play a crucial role in regulating gut microbiota and promoting the production of short-chain fatty acids, which can effectively treat various diseases such as diabetes, obesity, cancer, inflammation, and immunodeficiency. Further research should focus on elucidating the detailed mechanism of how dietary fibers impact diseases related to gut microbiota-mediated short-chain fatty acids.