Bacterial microcompartments: tiny organelles with big potential

Genetic characterization of a glycyl radical microcompartment used for 1,2-propanediol fermentation by uropathogenic Escherichia coli CFT073

(2020) Alex P. Lundin et al.   JOURNAL OF BACTERIOLOGY

Functionalization of Bacterial Microcompartment Shell Proteins With Covalently Attached Heme

(2020) Jingcheng Huang et al.   Frontiers in Bioengineering and Biotechnology

A genomic integration platform for heterologous cargo encapsulation in 1,2-propanediol utilization bacterial microcompartments

(2020) Taylor M. Nichols et al.   BIOCHEMICAL ENGINEERING JOURNAL

Apparent size and morphology of bacterial microcompartments varies with technique

(2020) Nolan W. Kennedy et al.   PLoS One

Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization

(2020) Jessica M. Ochoa et al.   PROTEIN SCIENCE

Self-assembling Shell Proteins PduA and PduJ have Essential and Redundant Roles in Bacterial Microcompartment Assembly

(2020) Nolan W. Kennedy et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Characterization of a Synthetic Tandem-Domain Bacterial Microcompartment Shell Protein Capable of Forming Icosahedral Shell Assemblies

(2019) Markus Sutter et al.   ACS Synthetic Biology

The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly

(2019) Basil J. Greber et al.   STRUCTURE

Bacterial microcompartment-mediated ethanolamine metabolism in E. coli urinary tract infection

(2019) Katherine Dadswell et al.   INFECTION AND IMMUNITY

Inflammation associated ethanolamine facilitates infection by Crohn's disease-linked adherent-invasive Escherichia coli

(2019) Michael J. Ormsby et al.   EBioMedicine

A designed bacterial microcompartment shell with tunable composition and precision cargo loading

(2019) Bryan Ferlez et al.   METABOLIC ENGINEERING

Developing a Protein Scaffolding System for Rapid Enzyme Immobilization and Optimization of Enzyme Functions for Biocatalysis

(2019) Guoqiang Zhang et al.   ACS Synthetic Biology

Engineering the PduT shell protein to modify the permeability of the 1,2-propanediol microcompartment of Salmonella

(2019) Chiranjit Chowdhury et al.   MICROBIOLOGY-SGM

Visualizing in Vivo Dynamics of Designer Nanoscaffolds

(2019) Eric J. Young et al.   NANO LETTERS

Bacterial microcompartments

(2018) Cheryl A. Kerfeld et al.   NATURE REVIEWS MICROBIOLOGY

Programmed loading and rapid purification of engineered bacterial microcompartment shells

(2018) Andrew Hagen et al.   Nature Communications

Self-Assembling Protein Scaffold System for Easy in Vitro Coimmobilization of Biocatalytic Cascade Enzymes

(2018) Guoqiang Zhang et al.   ACS Catalysis

Spatially organizing biochemistry: choosing a strategy to translate synthetic biology to the factory

(2018) Christopher M. Jakobson et al.   Scientific Reports

Building a toolbox of protein scaffolds for future immobilization of biocatalysts

(2018) Sarah Schmidt-Dannert et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments

(2018) Matthew J. Lee et al.   Nature Communications

In Vitro Assembly of Diverse Bacterial Microcompartment Shell Architectures

(2018) Andrew R. Hagen et al.   NANO LETTERS

Molecular Dynamics Simulations of Selective Metabolite Transport across the Propanediol Bacterial Microcompartment Shell

(2017) Jiyong Park et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm

(2017) Matthew J Lee et al.   Nature Chemical Biology

De novo design of signal sequences to localize cargo to the 1,2-propanediol utilization microcompartment

(2017) Christopher M. Jakobson et al.   PROTEIN SCIENCE

Assembly principles and structure of a 6.5-MDa bacterial microcompartment shell

(2017) Markus Sutter et al.   SCIENCE

Construction of Recombinant Pdu Metabolosome Shells for Small Molecule Production in Corynebacterium glutamicum

(2017) Isabel Huber et al.   ACS Synthetic Biology

Evidence for Improved Encapsulated Pathway Behavior in a Bacterial Microcompartment through Shell Protein Engineering

(2017) Marilyn F. Slininger Lee et al.   ACS Synthetic Biology

A systems-level model reveals that 1,2-Propanediol utilization microcompartments enhance pathway flux through intermediate sequestration

(2017) Christopher M. Jakobson et al.   PLoS Computational Biology

Encapsulation of multiple cargo proteins within recombinant Eut nanocompartments

(2016) Maureen B. Quin et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Tuning the Catalytic Activity of Subcellular Nanoreactors

(2016) Christopher M. Jakobson et al.   JOURNAL OF MOLECULAR BIOLOGY

The PduL Phosphotransacylase Is Used To Recycle Coenzyme A within the Pdu Microcompartment

(2015) Yu Liu et al.   JOURNAL OF BACTERIOLOGY

Localization of Proteins to the 1,2-Propanediol Utilization Microcompartment by Non-native Signal Sequences Is Mediated by a Common Hydrophobic Motif

(2015) Christopher M. Jakobson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein

(2015) Michael C. Thompson et al.   PROTEIN SCIENCE

Structural Insights into Higher Order Assembly and Function of the Bacterial Microcompartment Protein PduA

(2014) Allan Pang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly of Robust Bacterial Microcompartment Shells Using Building Blocks from an Organelle of Unknown Function

(2014) Jonathan K. Lassila et al.   JOURNAL OF MOLECULAR BIOLOGY

Solution Structure of a Bacterial Microcompartment Targeting Peptide and Its Application in the Construction of an Ethanol Bioreactor

(2014) Andrew D. Lawrence et al.   ACS Synthetic Biology

A Taxonomy of Bacterial Microcompartment Loci Constructed by a Novel Scoring Method

(2014) Seth D. Axen et al.   PLoS Computational Biology

Biogenesis of a Bacterial Organelle: The Carboxysome Assembly Pathway

(2013) Jeffrey C. Cameron et al.   CELL

The Structure of CcmP, a Tandem Bacterial Microcompartment Domain Protein from the β-Carboxysome, Forms a Subcompartment Within a Microcompartment

(2013) Fei Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineered Protein Nano-Compartments for Targeted Enzyme Localization

(2012) Swati Choudhary et al.   PLoS One

The N-Terminal Region of the Medium Subunit (PduD) Packages Adenosylcobalamin-Dependent Diol Dehydratase (PduCDE) into the Pdu Microcompartment

(2011) C. Fan et al.   JOURNAL OF BACTERIOLOGY

Structural Insight into the Mechanisms of Transport across theSalmonella entericaPdu Microcompartment Shell

(2010) Christopher S. Crowley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short N-terminal sequences package proteins into bacterial microcompartments

(2010) C. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemical and Structural Insights into Bacterial Organelle Form and Biogenesis

(2008) Joshua B. Parsons et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomic-Level Models of the Bacterial Carboxysome Shell

(2008) S. Tanaka et al.   SCIENCE