Serotonin neurons modulate learning rate through uncertainty

Disruption of model-based decision making by silencing of serotonin neurons in the dorsal raphe nucleus

(2021) Yu Ohmura et al.   CURRENT BIOLOGY

Temporal and state abstractions for efficient learning, transfer, and composition in humans.

(2021) Liyu Xia et al.   PSYCHOLOGICAL REVIEW

A distributional code for value in dopamine-based reinforcement learning

(2020) Will Dabney et al.   NATURE

Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input

(2020) Zohre Azimi et al.   eLife

Delta glutamate receptor conductance drives excitation of mouse dorsal raphe neurons

(2020) Stephanie C Gantz et al.   eLife

How Outcome Uncertainty Mediates Attention, Learning, and Decision-Making

(2020) Ilya E. Monosov   TRENDS IN NEUROSCIENCES

Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys

(2020) Marco K. Wittmann et al.   Nature Communications

Comprehensive topographical map of the serotonergic fibers in the male mouse brain

(2020) Janak R. Awasthi et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Area-Specificity and Plasticity of History-Dependent Value Coding During Learning

(2019) Ryoma Hattori et al.   CELL

Adaptive learning under expected and unexpected uncertainty

(2019) Alireza Soltani et al.   NATURE REVIEWS NEUROSCIENCE

Stable Representations of Decision Variables for Flexible Behavior

(2019) Bilal A. Bari et al.   NEURON

Flexible combination of reward information across primates

(2019) Shiva Farashahi et al.   Nature Human Behaviour

Task complexity interacts with state-space uncertainty in the arbitration between model-based and model-free learning

(2019) Dongjae Kim et al.   Nature Communications

Prefrontal cortex as a meta-reinforcement learning system

(2018) Jane X. Wang et al.   NATURE NEUROSCIENCE

Balancing New against Old Information: The Role of Puzzlement Surprise in Learning

(2018) Mohammadjavad Faraji et al.   NEURAL COMPUTATION

Volatility Facilitates Value Updating in the Prefrontal Cortex

(2018) Bart Massi et al.   NEURON

Mechanisms Underlying Serotonergic Excitation of Callosal Projection Neurons in the Mouse Medial Prefrontal Cortex

(2018) Emily K. Stephens et al.   Frontiers in Neural Circuits

Activation of serotonin neurons promotes active persistence in a probabilistic foraging task

(2018) Eran Lottem et al.   Nature Communications

An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals

(2018) Kiyohito Iigaya et al.   Nature Communications

Striatal action-value neurons reconsidered

(2018) Lotem Elber-Dorozko et al.   eLife

Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems

(2018) Jing Ren et al.   CELL

Dissociable effects of acute SSRI (escitalopram) on executive, learning and emotional functions in healthy humans

(2018) Nikolina Skandali et al.   NEUROPSYCHOPHARMACOLOGY

Novelty, Salience, and Surprise Timing Are Signaled by Neurons in the Basal Forebrain

(2018) Kaining Zhang et al.   CURRENT BIOLOGY

Serotonin Decreases the Gain of Visual Responses in Awake Macaque V1

(2017) Lenka Seillier et al.   JOURNAL OF NEUROSCIENCE

Dorsal hippocampus contributes to model-based planning

(2017) Kevin J Miller et al.   NATURE NEUROSCIENCE

Organization of Functional Long-Range Circuits Controlling the Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus

(2017) Li Zhou et al.   Cell Reports

Activity patterns of serotonin neurons underlying cognitive flexibility

(2017) Sara Matias et al.   eLife

Cholinergic and serotonergic modulation of visual information processing in monkey V1

(2016) Satoshi Shimegi et al.   JOURNAL OF PHYSIOLOGY-PARIS

Activation of raphe nuclei triggers rapid and distinct effects on parallel olfactory bulb output channels

(2016) Vikrant Kapoor et al.   NATURE NEUROSCIENCE

Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids

(2016) Sean D. Geddes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serotonin neurons in the dorsal raphe nucleus encode reward signals

(2016) Yi Li et al.   Nature Communications

A dynamic code for economic object valuation in prefrontal cortex neurons

(2016) Ken-Ichiro Tsutsui et al.   Nature Communications

The First Structure–Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs

(2015) Xin Chen et al.   ACS Chemical Neuroscience

5-HT1A Receptor-Mediated Autoinhibition and the Control of Serotonergic Cell Firing

(2015) Rodrigo Andrade et al.   ACS Chemical Neuroscience

Central Cholinergic Neurons Are Rapidly Recruited by Reinforcement Feedback

(2015) Balázs Hangya et al.   CELL

Activation of Dorsal Raphe Serotonergic Neurons Promotes Waiting but Is Not Reinforcing

(2015) Madalena S. Fonseca et al.   CURRENT BIOLOGY

Scaling prediction errors to reward variability benefits error-driven learning in humans

(2015) Kelly M. J. Diederen et al.   JOURNAL OF NEUROPHYSIOLOGY

Valence-dependent influence of serotonin depletion on model-based choice strategy

(2015) Y Worbe et al.   MOLECULAR PSYCHIATRY

A network model of basal ganglia for understanding the roles of dopamine and serotonin in reward-punishment-risk based decision making

(2015) Pragathi P. Balasubramani et al.   Frontiers in Computational Neuroscience

Activity of Raphé Serotonergic Neurons Controls Emotional Behaviors

(2015) Anne Teissier et al.   Cell Reports

Serotonergic neurons signal reward and punishment on multiple timescales

(2015) Jeremiah Y Cohen et al.   eLife

Optogenetic Activation of Dorsal Raphe Serotonin Neurons Enhances Patience for Future Rewards

(2014) Kayoko W. Miyazaki et al.   CURRENT BIOLOGY

Dorsal Raphe Neurons Signal Reward through 5-HT and Glutamate

(2014) Zhixiang Liu et al.   NEURON

Functionally Dissociable Influences on Learning Rate in a Dynamic Environment

(2014) Joseph T. McGuire et al.   NEURON

Neural Computations Underlying Arbitration between Model-Based and Model-free Learning

(2014) Sang Wan Lee et al.   NEURON

A memory of errors in sensorimotor learning

(2014) D. J. Herzfeld et al.   SCIENCE

Activity-dependent serotonergic excitation of callosal projection neurons in the mouse prefrontal cortex

(2014) Emily K. Stephens et al.   Frontiers in Neural Circuits

Organization of Monosynaptic Inputs to the Serotonin and Dopamine Neuromodulatory Systems

(2014) Sachie K. Ogawa et al.   Cell Reports

Association with Reward Negatively Modulates Short Latency Phasic Conditioned Responses of Dorsal Raphe Nucleus Neurons in Freely Moving Rats

(2013) Y. Li et al.   JOURNAL OF NEUROSCIENCE

The Neural Representation of Unexpected Uncertainty during Value-Based Decision Making

(2013) Elise Payzan-LeNestour et al.   NEURON

Mice infer probabilistic models for timing

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serotonin Selectively Modulates Reward Value in Human Decision-Making

(2012) B. Seymour et al.   JOURNAL OF NEUROSCIENCE

Neural Prediction Errors Reveal a Risk-Sensitive Reinforcement-Learning Process in the Human Brain

(2012) Y. Niv et al.   JOURNAL OF NEUROSCIENCE

Neuron-type-specific signals for reward and punishment in the ventral tegmental area

(2012) Jeremiah Y. Cohen et al.   NATURE

Rational regulation of learning dynamics by pupil-linked arousal systems

(2012) Matthew R Nassar et al.   NATURE NEUROSCIENCE

Knowing how much you don't know: a neural organization of uncertainty estimates

(2012) Dominik R. Bach et al.   NATURE REVIEWS NEUROSCIENCE

Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders

(2012) Klaus-Peter Lesch et al.   NEURON

Neuromodulation of Neuronal Circuits: Back to the Future

(2012) Eve Marder   NEURON

Serotonin Modulates the Effects of Pavlovian Aversive Predictions on Response Vigor

(2012) Molly J Crockett et al.   NEUROPSYCHOPHARMACOLOGY

Selective serotonergic excitation of callosal projection neurons

(2012) Daniel Avesar et al.   Frontiers in Neural Circuits

Activation of Dorsal Raphe Serotonin Neurons Underlies Waiting for Delayed Rewards

(2011) K. Miyazaki et al.   JOURNAL OF NEUROSCIENCE

Serotonergic regulation of neuronal excitability in the prefrontal cortex

(2011) Rodrigo Andrade   NEUROPHARMACOLOGY

Risk, Unexpected Uncertainty, and Estimation Uncertainty: Bayesian Learning in Unstable Settings

(2011) Elise Payzan-LeNestour et al.   PLoS Computational Biology

Enhancement of Spatial Reversal Learning by 5-HT2C Receptor Antagonism Is Neuroanatomically Specific

(2010) V. Boulougouris et al.   JOURNAL OF NEUROSCIENCE

Serotonin Modulates Sensitivity to Reward and Negative Feedback in a Probabilistic Reversal Learning Task in Rats

(2010) Andrea Bari et al.   NEUROPSYCHOPHARMACOLOGY

Pharmacological or Genetic Inactivation of the Serotonin Transporter Improves Reversal Learning in Mice

(2009) J. L. Brigman et al.   CEREBRAL CORTEX

Serotonin Affects Association of Aversive Outcomes to Past Actions

(2009) S. C. Tanaka et al.   JOURNAL OF NEUROSCIENCE

Prefrontal and striatal dopaminergic genes predict individual differences in exploration and exploitation

(2009) Michael J Frank et al.   NATURE NEUROSCIENCE

Genetic variation in dopaminergic neuromodulation influences the ability to rapidly and flexibly adapt decisions

(2009) L. K. Krugel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reward-Dependent Modulation of Neuronal Activity in the Primate Dorsal Raphe Nucleus

(2008) K. Nakamura et al.   JOURNAL OF NEUROSCIENCE

Value Representations in the Primate Striatum during Matching Behavior

(2008) Brian Lau et al.   NEURON