Safety and efficacy of ampreloxetine in symptomatic neurogenic orthostatic hypotension: a phase 2 trial

Pharmacokinetics and pharmacodynamics of ampreloxetine, a novel, selective norepinephrine reuptake inhibitor, in symptomatic neurogenic orthostatic hypotension

(2021) Arthur Lo et al.   CLINICAL AUTONOMIC RESEARCH

Baroreflex Dysfunction

(2020) Horacio Kaufmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prevention of Falls in Community-Dwelling Older Adults

(2020) David A. Ganz et al.   NEW ENGLAND JOURNAL OF MEDICINE

The impact of supine hypertension on target organ damage and survival in patients with synucleinopathies and neurogenic orthostatic hypotension

(2020) Jose-Alberto Palma et al.   PARKINSONISM & RELATED DISORDERS

Pharmacokinetics of Ampreloxetine, a Norepinephrine Reuptake Inhibitor, in Healthy Subjects and Adults with Attention-Deficit/Hyperactive Disorder or Fibromyalgia Pain

(2020) Jitendra Kanodia et al.   CLINICAL PHARMACOKINETICS

Management of Orthostatic Hypotension, Postprandial Hypotension, and Supine Hypertension

(2020) Cyndya A. Shibao et al.   SEMINARS IN NEUROLOGY

Management of supine hypertension in patients with neurogenic orthostatic hypotension

(2019) Jens Jordan et al.   JOURNAL OF HYPERTENSION

Initiation of droxidopa during hospital admission for management of refractory neurogenic orthostatic hypotension in severely ill patients

(2019) Katherine E. McDonell et al.   Journal of Clinical Hypertension

Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension

(2019) Jung‐Ick Byun et al.   Annals of Clinical and Translational Neurology

Orthostatic heart rate changes in patients with autonomic failure caused by neurodegenerative synucleinopathies

(2018) Lucy Norcliffe-Kaufmann et al.   ANNALS OF NEUROLOGY

Characterization of the symptoms of neurogenic orthostatic hypotension and their impact from a survey of patients and caregivers

(2018) Daniel O. Claassen et al.   BMC Neurology

Supine plasma NE predicts the pressor response to droxidopa in nOH

(2018) Jose-Alberto Palma et al.   NEUROLOGY

Fludrocortisone Is Associated With a Higher Risk of All‐Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension

(2017) Carlos G. Grijalva et al.   Journal of the American Heart Association

Norepinephrine deficiency with normal blood pressure control in congenital insensitivity to pain with anhidrosis

(2015) Lucy Norcliffe-Kaufmann et al.   ANNALS OF NEUROLOGY

Multiple system atrophy: Using clinical pharmacology to reveal pathophysiology

(2015) Jens Jordan et al.   CLINICAL AUTONOMIC RESEARCH

Preclinical to Clinical Translation of CNS Transporter Occupancy of TD-9855, a Novel Norepinephrine and Serotonin Reuptake Inhibitor

(2015) Jacqueline AM Smith et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Orthostatic Hypotension in Parkinson Disease: How Much You Fall or How Low You Go?

(2015) Jose-Alberto Palma et al.   MOVEMENT DISORDERS

Multiple-System Atrophy

(2015) Alessandra Fanciulli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of Atomoxetine Versus Midodrine for the Treatment of Orthostatic Hypotension in Autonomic Failure

(2014) Claudia E. Ramirez et al.   HYPERTENSION

Norepinephrine transporter function and human cardiovascular disease

(2012) C. Schroeder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale

(2011) Horacio Kaufmann et al.   CLINICAL AUTONOMIC RESEARCH

Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome

(2011) Roy Freeman et al.   CLINICAL AUTONOMIC RESEARCH

Prevalence of orthostatic hypotension

(2008) Phillip A. Low   CLINICAL AUTONOMIC RESEARCH

Second consensus statement on the diagnosis of multiple system atrophy

(2008) S. Gilman et al.   NEUROLOGY

Axonal  -synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease

(2007) S. Orimo et al.   BRAIN