Article
Immunology
Anders Dahl, Vance G. Fowler, Jose M. Miro, Niels E. Bruun
Summary: By including Enterococcus faecalis as a typical endocarditis bacterium regardless of the place of acquisition or the portal of entry, the sensitivity to correctly identify definite endocarditis can be improved from 70% (modified Duke criteria) to 96% (enterococcal adjusted Duke criteria) based on data from a prospective study of 344 patients with E. faecalis bacteremia evaluated with echocardiography.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Biotechnology & Applied Microbiology
Jie Luo, Hongfei Zhang, Jiachen Lu, ChaoLin Ma, Tingtao Chen
Summary: Engineered strain Lactobacillus plantarum-pMG36e-GLP-1 was found to significantly reduce postprandial hyperglycaemia in T2DM monkeys. The study showed that this strain impacted the gut microbial composition and faecal metabolomic profile, indicating its potential as a novel candidate for diabetes treatment.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY
(2021)
Article
Business
Lauren Labrecque, Ereni Markos, Mujde Yuksel, Tracy A. Khan
Summary: Social media provides a platform for brands to strengthen their identities and engage positively with customers. However, it also exposes brands to the risk of negative comments that can harm their reputation. Surprisingly, these attempts to destroy value may actually result in value creation for the brand.
JOURNAL OF INTERACTIVE MARKETING
(2022)
Article
Microbiology
Qi Tang, Yingying Hao, Lu Wang, Chao Lu, Ming Li, Zaifeng Si, Xiaoben Wu, Zhiming Lu
Summary: In this study, a novel bacterial strain Lactobacillus paracasei LP10266 was found to have potential pathogenic traits, including sensitivity to multiple antibiotics, strong biofilm formation ability, and adherence to human vascular endothelial cells. This enhances awareness of L. paracasei infections and suggests the strain may be a risk factor for patients with cardiac disease and inguinal hernia repair history.
Article
Food Science & Technology
Jinsong Wang, Lanming Chen
Summary: The three-layer nano protectant containing trehalose, skim milk powder, phytoglycogen nanoparticles, and Pickering emulsions is found to have significant protective effects on Lactobacillus casei, making it suitable for use in feed and functional food products.
Article
Microbiology
Hiroyuki Kusada, Kana Morinaga, Hideyuki Tamaki
Summary: This study demonstrated that Lactobacillus gasseri JCM1131(T) possesses bile salt hydrolase (BSH) activity and bile salt resistance capability, highlighting its importance as a probiotic strain.
Article
Chemistry, Multidisciplinary
Wenqian Huang, Yirong Zhang, Zhi Li, Minjie Li, Fangfang Li, Monika Mortimer, Liang-Hong Guo
Summary: Medical applications of nanotechnology show promise, but the effects of nanodrugs on human microbiota have not been fully considered. This study found that medically relevant nanoparticles can affect the metabolism of beneficial bacteria and potentially alter the microbiota and immune signaling.
Article
Biotechnology & Applied Microbiology
Mengmeng Wang, Tongyuan Hu, Xiaoqian Lin, Hewei Liang, Wenxi Li, Shaowei Zhao, Yiyi Zhong, Haifeng Zhang, Lan Ge, Xin Jin, Liang Xiao, Yuanqiang Zou
Summary: In this study, a cholesterol-lowering bacterium, Lactobacillus gasseri TF08-1, was isolated from the feces of a healthy adolescent, and its probiotic potentials were evaluated. The strain showed the ability to utilize various carbon sources and had high bile salt hydrolase activity. It also demonstrated a significant cholesterol-reducing effect. These findings suggest that L. gasseri TF08-1 could be considered as a safe candidate for probiotic, especially in the biotherapeutic treatment of metabolic diseases.
ENZYME AND MICROBIAL TECHNOLOGY
(2023)
Article
Medicine, General & Internal
Mahmoud Diab, Marcus Franz, Stefan Hagel, Albrecht Guenther, Antonio Struve, Rita Musleh, Anika Penzel, Christoph Sponholz, Thomas Lehmann, Henning Kuehn, Karim Ibrahim, Marcus Jahnecke, Holger Sigusch, Henning Ebelt, Gloria Faerber, Otto W. Witte, Bettina Loeffler, Michael Bauer, Mathias W. Pletz, P. Christian Schulze, Torsten Doenst
Summary: Establishing an endocarditis network led to earlier referral of patients with fewer pre-operative complications. Adherence to recommendations of the endocarditis team was associated with lower post-operative stroke and in-hospital mortality, as well as improved 5-year survival rates.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Ali Rahman, Sura Alqaisi, Jayant Nath
Summary: This article presents a rare case of Lactobacillus casei endocarditis in a 71-year-old immunocompromised female. The patient had a productive cough and low-grade fever. Blood cultures showed resistance of L. casei to vancomycin and meropenem. After successful removal of vegetations, valve replacement was performed. The patient was treated with daptomycin for six weeks and recovered.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Editorial Material
Dermatology
Sarah Borg Grech, David Pisani, James Degaetano, Michael J. Boffa
Summary: We present a case of a middle-aged woman with multiple indurated areas of hair loss on her scalp. Dermoscopic inspection revealed arborizing vessels on an erythematous background. Nodules were also found on the nape of the neck and right breast. Punch biopsies showed diffuse infiltration of the dermis by neoplastic cells with moderate nuclear pleomorphism, abundant eosinophilic cytoplasm and brisk mitotic activity.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2023)
Article
Chemistry, Medicinal
Alf Claesson, Kevin Parkes
Summary: This article discusses the mechanisms of reactive metabolite formation, focusing on the enzymatic oxidation of alkyl groups on aromatics and the production of reactive metabolites such as quinone methides and benzylic alcohol sulfates. It also speculates that some older drugs may form unreported methides. Additionally, the article reports several DFT calculations of changes in free energy.
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Development Studies
Mohammad Abul Kashem, Mohammad Mafizur Rahman, Rasheda Khanam
Summary: This article explores the link between environmental degradation and agricultural trade balance (ATB) using data from Australia. The findings suggest that improving the ATB is harmful for the Australian environment, and economic activities related to agricultural imports are more environmentally efficient than export activities. The study also validates the EKC hypothesis and highlights the importance of national income in relation to environmental pollution.
SUSTAINABLE DEVELOPMENT
(2023)
Article
Immunology
Tomomi Kawai, Tomoko Ohshima, Takeshi Tanaka, Satoshi Ikawa, Atsushi Tani, Naoya Inazumi, Ryoichi Shin, Yukie Itoh, Karen Meyer, Nobuko Maeda
Summary: Periodontal disease is caused by oral microbiota imbalance, and the use of antibiotics and disinfectants for treatment can lead to drug-resistant bacteria and allergies. Studies have found that probiotics have potential as an alternative therapy for periodontitis, but the mechanism is not clear. This study identified and analyzed a cyclic dipeptide produced by a probiotic strain, which showed antibacterial activity against periodontal pathogens. This discovery may contribute to a better understanding of the antibacterial mechanism and prevention of periodontal disease.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Chemistry, Physical
Shagufta Fahmid, Rukhsana Jabeen, Saima Mehar, Naheed Sajjad, Farida Behlil, Mussarat Riaz, Neelofer Jameel, Hina Ishtiyaq, Farah Mukhtar, Noureen Khan, Jaffar Ali
Summary: In the era of antimicrobial resistance, the use of phytochemicals from Calotropis procera to synthesize antifungal silver nanoparticles (AgNPs) is crucial. The AgNPs display multiple Surface Plasmon Resonance peaks and have varying shapes, making them effective in combating pathogenic fungi. Additionally, the phytochemicals serve as capping and stabilizing agents for the AgNPs, enhancing their antifungal activity.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
