Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

Injection of ROS‐Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair

(2021) Zhenhua Li et al.   ADVANCED FUNCTIONAL MATERIALS

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

(2021) Dashuai Zhu et al.   Nature Communications

Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out?

(2021) Dashuai Zhu et al.   Cells

An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs

(2020) Ke Huang et al.   Science Translational Medicine

Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs

(2020) Teng Su et al.   ACS Biomaterials-Science & Engineering

Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure

(2019) Terrence M. Yau et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Chemical Engineering of Cell Therapy for Heart Diseases

(2019) Zhenhua Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

Self-assembling peptide hydrogel enables instant epicardial coating of the heart with mesenchymal stromal cells for the treatment of heart failure

(2018) Yuki Ichihara et al.   BIOMATERIALS

New Paradigms in Cell Therapy

(2018) Marcin Wysoczynski et al.   CIRCULATION RESEARCH

Minimally Invasive Delivery of Hydrogel-Encapsulated Amiodarone to the Epicardium Reduces Atrial Fibrillation

(2018) Jose R. Garcia et al.   Circulation-Arrhythmia and Electrophysiology

Cell therapy trials for heart regeneration — lessons learned and future directions

(2018) Philippe Menasché   Nature Reviews Cardiology

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

(2018) Junnan Tang et al.   Nature Biomedical Engineering

Improvement of Local Cell Delivery Using Helix Transendocardial Delivery Catheter in a Porcine Heart

(2017) Yoshiaki Mitsutake et al.   International Heart Journal

Non-invasive in vivo imaging of cardiac stem/progenitor cell biodistribution and retention after intracoronary and intramyocardial delivery in a swine model of chronic ischemia reperfusion injury

(2017) María Collantes et al.   Journal of Translational Medicine

A Regenerative Cardiac Patch Formed by Spray Painting of Biomaterials onto the Heart

(2017) Junnan Tang et al.   TISSUE ENGINEERING PART C-METHODS

Route of Delivery Modulates the Efficacy of Mesenchymal Stem Cell Therapy for Myocardial InfarctionNovelty and Significance

(2016) Anthony J. Kanelidis et al.   CIRCULATION RESEARCH

Emerging Concepts in Paracrine Mechanisms in Regenerative Cardiovascular Medicine and Biology

(2016) Conrad P. Hodgkinson et al.   CIRCULATION RESEARCH

Intrapericardial Delivery of Cardiosphere-Derived Cells: An Immunological Study in a Clinically Relevant Large Animal Model

(2016) Rebeca Blázquez et al.   PLoS One

Immunologic Network and Response to Intramyocardial CD34+ Stem Cell Therapy in Patients With Dilated Cardiomyopathy

(2015) Francois Haddad et al.   JOURNAL OF CARDIAC FAILURE

Intrapericardial Administration of Mesenchymal Stem Cells in a Large Animal Model: A Bio-Distribution Analysis

(2015) Rebeca Blázquez et al.   PLoS One

Mesenchymal Precursor Cells as Adjunctive Therapy in Recipients of Contemporary Left Ventricular Assist Devices

(2014) Deborah D. Ascheim et al.   CIRCULATION

Comparison of Transendocardial and Intracoronary CD34+ Cell Transplantation in Patients With Nonischemic Dilated Cardiomyopathy

(2013) B. Vrtovec et al.   CIRCULATION

Intracoronary Delivery of Autologous Cardiac Stem Cells Improves Cardiac Function in a Porcine Model of Chronic Ischemic Cardiomyopathy

(2013) Roberto Bolli et al.   CIRCULATION

Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel

(2012) Ke Cheng et al.   BIOMATERIALS

Effects of Intracoronary CD34 + Stem Cell Transplantation in Nonischemic Dilated Cardiomyopathy Patients

(2012) Bojan Vrtovec et al.   CIRCULATION RESEARCH

Early Stem Cell Engraftment Predicts Late Cardiac Functional Recovery

(2012) Junwei Liu et al.   Circulation-Cardiovascular Imaging

Intramyocardial Injection of Platelet Gel Promotes Endogenous Repair and Augments Cardiac Function in Rats With Myocardial Infarction

(2012) Ke Cheng et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Catheter-Deliverable Hydrogel Derived From Decellularized Ventricular Extracellular Matrix Increases Endogenous Cardiomyocytes and Preserves Cardiac Function Post-Myocardial Infarction

(2012) Jennifer M. Singelyn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intrapericardial Delivery of Gelfoam Enables the Targeted Delivery of Periostin Peptide after Myocardial Infarction by Inducing Fibrin Clot Formation

(2012) Brian D. Polizzotti et al.   PLoS One

Delivery of gelfoam-enabled cells and vectors into the pericardial space using a percutaneous approach in a porcine model

(2011) D Ladage et al.   GENE THERAPY

Assessment and Optimization of Cell Engraftment After Transplantation Into the Heart

(2010) John V. Terrovitis et al.   CIRCULATION RESEARCH

Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering

(2009) Jennifer M. Singelyn et al.   BIOMATERIALS

Engraftment, Differentiation, and Functional Benefits of Autologous Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy

(2009) Peter V. Johnston et al.   CIRCULATION

Noninvasive Quantification and Optimization of Acute Cell Retention by In Vivo Positron Emission Tomography After Intramyocardial Cardiac-Derived Stem Cell Delivery

(2009) John Terrovitis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy

(2008) Massimiliano Gnecchi et al.   CIRCULATION RESEARCH