ANGPTL4 accelerates KRASG12D-Induced acinar to ductal metaplasia and pancreatic carcinogenesis

ANGPTL 4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a

(2020) Kyung Hee Jung et al.   EMBO Molecular Medicine

Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-ALL Progression by Modulating CCL2 in Leukemia Cells

(2019) Zhenling Ma et al.   Cell Reports

Periostin and CA242 as potential diagnostic serum biomarkers complementing CA19.9 in detecting pancreatic cancer

(2018) Dong Dong et al.   CANCER SCIENCE

Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial–mesenchymal transition by inducing 14-3-3γ expression

(2017) Z Teo et al.   ONCOGENE

Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

(2016) Simone Hausmann et al.   AMERICAN JOURNAL OF PATHOLOGY

KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis

(2016) Daoyan Wei et al.   CANCER CELL

Cancer cells remodel themselves and vasculature to overcome the endothelial barrier

(2016) Anitha K. Shenoy et al.   CANCER LETTERS

RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4

(2016) Marie K. Kirby et al.   Molecular Oncology

Role of pancreatic stellate cells and periostin in pancreatic cancer progression

(2015) Yang Liu et al.   TUMOR BIOLOGY

Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer

(2015) HIROSHI KUBO et al.   Oncology Letters

Pancreatic Adenocarcinoma

(2015) David P. Ryan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutant KRAS–Induced Expression of ICAM-1 in Pancreatic Acinar Cells Causes Attraction of Macrophages to Expedite the Formation of Precancerous Lesions

(2014) Geou-Yarh Liou et al.   Cancer Discovery

What We Have Learned About Pancreatic Cancer From Mouse Models

(2012) Pedro A. Pérez–Mancera et al.   GASTROENTEROLOGY

Presence of Somatic Mutations in Most Early-Stage Pancreatic Intraepithelial Neoplasia

(2012) Mitsuro Kanda et al.   GASTROENTEROLOGY

An NF-κB pathway–mediated positive feedback loop amplifies Ras activity to pathological levels in mice

(2012) Jaroslaw Daniluk et al.   JOURNAL OF CLINICAL INVESTIGATION

Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

(2012) Meredith A. Collins et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging Roles of Angiopoietin-like 4 in Human Cancer

(2012) Ming Jie Tan et al.   MOLECULAR CANCER RESEARCH

Resistance to Fluid Shear Stress Is a Conserved Biophysical Property of Malignant Cells

(2012) J. Matthew Barnes et al.   PLoS One

Evaluation of TGFβ, XPO4, elF5A2 and ANGPTL4 as biomarkers in HCC

(2012) HAO ZHANG et al.   Experimental and Therapeutic Medicine

ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters

(2011) R.-L. Huang et al.   BLOOD

Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2−:H2O2 Ratio and Confers Anoikis Resistance to Tumors

(2011) Pengcheng Zhu et al.   CANCER CELL

ANGPTL4 Induction by Prostaglandin E2 under Hypoxic Conditions Promotes Colorectal Cancer Progression

(2011) S.-H. Kim et al.   CANCER RESEARCH

Pancreatic ductal adenocarcinoma and acinar cells: a matter of differentiation and development?

(2011) Ilse Rooman et al.   GUT

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

(2011) H Zhang et al.   ONCOGENE

Expression of angiopoietin-like 4 (ANGPTL4) in human colorectal cancer: ANGPTL4 promotes venous invasion and distant metastasis

(2011) Nakayama   ONCOLOGY REPORTS

Periostin expression and epithelial-mesenchymal transition in cancer: a review and an update

(2011) Laura Morra et al.   VIRCHOWS ARCHIV

Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion

(2010) Nakayama   ONCOLOGY REPORTS

Determination of Angptl4 mRNA as a Diagnostic Marker of Primary and Metastatic Clear Cell Renal-Cell Carcinoma

(2010) Jérôme Verine et al.   PLoS One

Ras Activity Levels Control the Development of Pancreatic Diseases

(2009) Baoan Ji et al.   GASTROENTEROLOGY

Loss of the Acinar-Restricted Transcription Factor Mist1 Accelerates Kras-Induced Pancreatic Intraepithelial Neoplasia

(2009) Guanglu Shi et al.   GASTROENTEROLOGY

KRAS2 Mutations in Human Pancreatic Acinar-Ductal Metaplastic Lesions Are Limited to Those with PanIN: Implications for the Human Pancreatic Cancer Cell of Origin

(2009) C. Shi et al.   MOLECULAR CANCER RESEARCH

Acquisition of anoikis resistance reveals a synoikis-like survival style in BEL7402 hepatoma cells

(2008) Zhiyong Zhang et al.   CANCER LETTERS

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

(2008) J.-P. De La O et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA