The novel long noncoding RNA AU021063, induced by IL-6/Arid5a signaling, exacerbates breast cancer invasion and metastasis by stabilizing Trib3 and activating the Mek/Erk pathway

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

In silico identification of MAPK14-related lncRNAs and assessment of their expression in breast cancer samples

(2020) Sepideh Dashti et al.   Scientific Reports

Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer

(2020) Poonam Sarode et al.   Science Advances

Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway

(2020) Shuang Wang et al.   Cancer Cell International

LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling

(2020) Viorel Simion et al.   JCI Insight

MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer

(2019) Nicholas G. Nickols et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Feedback regulation of Arid5a and Ppar-γ2 maintains adipose tissue homeostasis

(2019) Jaya Prakash Chalise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long non-coding RNA: Classification, biogenesis and functions in blood cells

(2019) Swati Dahariya et al.   MOLECULAR IMMUNOLOGY

TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription

(2019) Jin-mei Yu et al.   Nature Communications

Arid5a stabilizes OX40 mRNA in murine CD4+ T cells by recognizing a stem-loop structure in its 3′UTR

(2018) Hamza Hanieh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

LncRNA HOTAIR contributes to the malignancy of hepatocellular carcinoma by enhancing epithelial-mesenchymal transition via sponging miR-23b-3p from ZEB1

(2018) Tao Yang et al.   GENE

Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a

(2018) Mitsuru Higa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifaceted Roles of Interleukin-6 in Adipocyte–Breast Cancer Cell Interaction

(2018) Jones Gyamfi et al.   Translational Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer

(2018) Ali Masjedi et al.   BIOMEDICINE & PHARMACOTHERAPY

iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

(2018) Steven Xijin Ge et al.   BMC BIOINFORMATICS

TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a

(2017) Kishan K. Nyati et al.   NUCLEIC ACIDS RESEARCH

Targeting of crosstalk between tumor and tumor microenvironment by β-D mannuronic acid (M2000) in murine breast cancer model

(2017) Fatemeh Hosseini et al.   Cancer Medicine

Arid5a regulates naive CD4+T cell fate through selective stabilization of Stat3 mRNA

(2016) Kazuya Masuda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner

(2016) Wen-Tao Wang et al.   Journal of Hematology & Oncology

Arid5a exacerbates IFN-γ–mediated septic shock by stabilizing T-bet mRNA

(2016) Mohammad Mahabub-Uz Zaman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breast cancer in China

(2014) Lei Fan et al.   LANCET ONCOLOGY

Long non-coding RNA-LET is a positive prognostic factor and exhibits tumor-suppressive activity in gallbladder cancer

(2014) Ming-zhe Ma et al.   MOLECULAR CARCINOGENESIS

Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo

(2013) Kazuya Masuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncovering the role of genomic “dark matter” in human disease

(2012) Lance Martin et al.   JOURNAL OF CLINICAL INVESTIGATION

TRB3 interacts with SMAD3 promoting tumor cell migration and invasion

(2011) F. Hua et al.   JOURNAL OF CELL SCIENCE

Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription

(2011) Katsuhiko Amano et al.   MOLECULAR BIOLOGY OF THE CELL

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

Interleukin-6 Increases Expression and Secretion of Cathepsin B by Breast Tumor-Associated Monocytes

(2010) Mona Mohamed et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

GANP-mediated Recruitment of Activation-induced Cytidine Deaminase to Cell Nuclei and to Immunoglobulin Variable Region DNA

(2010) Kazuhiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells

(2009) M Walter et al.   ONCOGENE