Article
Public, Environmental & Occupational Health
Fiona Vanobberghen, Maja Weisser, Bryson Kasuga, Andrew Katende, Manuel Battegay, Marcel Tanner, Tracy R. Glass
Summary: The study aimed to assess mortality in rural Tanzania among HIV-infected individuals, considering unseen deaths among participants lost to follow-up. Adjusting for unseen deaths among participants LTFU approximately doubled the estimated 5-year mortality rates.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Medicine, General & Internal
Adrian Carballo-Casla, Rosario Ortola, Esther Garcia-Esquinas, Andreia Oliveira, Mercedes Sotos-Prieto, Carla Lopes, Esther Lopez-Garcia, Fernando Rodriguez-Artalejo
Summary: The study shows that higher adherence to the Southern European Atlantic Diet (SEAD) is associated with lower all-cause mortality in older adults, with moderate wine consumption being particularly beneficial. The protective association between SEAD and all-cause death is similar to that of the Mediterranean Diet Adherence Screener and the Alternate Healthy Eating Index.
Article
Immunology
Jyoti Sehjal, Linda D. Sharples, Ruth H. Keogh, Kate Walker, Andreas Prachalias, Nigel Heaton, Tommy Ivanics, Jan van der Meulen, David Wallace
Summary: This study reveals time-varying differences in the hazard of all-cause mortality after liver transplantation between hepatocellular carcinoma (HCC) recipients and non-HCC recipients. It also provides evidence that some HCC patients have extra-hepatic spread at the time of transplantation, which has implications for post-transplant surveillance protocols.
Article
Urology & Nephrology
Wai H. Lim, Jenny H. C. Chen, Kimberley Minas, David W. Johnson, Maleeka Ladhani, Esther Ooi, Neil Boudville, Carmel Hawley, Andrea K. Viecelli, Matthew Roberts, Kate Wyburn, Rachael Walker, Monique Borlace, Helen Pilmore, Christopher E. Davies, Charmaine E. Lok, Armando Teixeira-Pinto, Germaine Wong
Summary: This study investigates the cause-specific mortality rates between male and female dialysis patients in Australia and New Zealand from 1998 to 2018. It found that female patients had a higher risk of all-cause mortality in the first 5 years after dialysis initiation, primarily due to mortality from infections and dialysis withdrawals.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2023)
Article
Dermatology
Oras A. Alabas, Kayleigh J. Mason, Zenas Z. N. Yiu, Richard B. Warren, Mark Lunt, Catherine H. Smith, Christopher E. M. Griffiths, BADBIR Study Grp
Summary: The aim of this study was to determine the real-world effectiveness and survival of methotrexate (MTX) and adalimumab (ADA) in patients with moderate-to-severe psoriasis registered in BADBIR. The study found that patients on ADA were twice as likely to be clear or nearly clear of psoriasis and were less likely to discontinue their medication than patients on MTX.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Habiel Benjamin Luvanda, Elevatus Nkebukwa Mukyanuzi, Rocky R. J. Akarro
Summary: This study used a joint survival model to analyze the association between long-term viral load and time to death, and found that age and gender are important factors affecting the risk of death in HIV patients.
Article
Public, Environmental & Occupational Health
Menglan Pang, James A. Hanley
Summary: Epidemiologists commonly use hazard ratio or mortality rate ratio to measure differences in all-cause mortality rates, but seldom translate them into age-, time-, or probability-based measures for easier communication. These translation tools are applicable when the mortality rate ratio is constant over age and the rates themselves are log-linear in age.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Medical Laboratory Technology
Xuan Ji, Shixuan Peng
Summary: This study found a positive correlation between serum anion gap levels and all-cause mortality in unselected adult patients, with higher levels of serum anion gap associated with increased patient mortality.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2023)
Article
Nutrition & Dietetics
Bo Mi Song, Jung Hyun Lee, Hae Dong Woo, Mi Jin Cho, Sung Soo Kim
Summary: This study aimed to examine the association between HbA1c levels and mortality in middle-aged and older Koreans. The study found a U-shaped relationship between HbA1c levels and all-cause mortality, increased risk of cancer mortality in both low and high HbA1c groups, and increased risk of CVD mortality only in the high HbA1c group. Particularly, individuals with liver diseases and low HbA1c levels had a higher risk of all-cause mortality.
NUTRITION & METABOLISM
(2022)
Article
Public, Environmental & Occupational Health
Juyeong Kim, Eun-Cheol Park
Summary: This study aimed to assess the specific associations between stroke and all-cause and cause-specific mortality among Korean adults. The results showed that stroke was associated with a higher risk of all-cause, natural cause, and suicide mortality.
JOURNAL OF PUBLIC HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Shixuan Peng, Jianxing Peng, Lianju Yang, Weiqi Ke
Summary: This study examines the relationship between serum sodium levels and all-cause mortality in congestive heart failure (CHF) patients. The results revealed a U-shaped relationship between serum sodium levels and all-cause mortality, with both low (<137.5 mmol/L) and high (>= 137.5 mmol/L) levels associated with increased mortality rates.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Food Science & Technology
Hyein Jung, Sangah Shin
Summary: This study finds that higher intake of tomatoes and lycopene is inversely associated with the risk of cardiovascular disease (CVD) mortality, and lycopene consumption is associated with a lower risk of all-cause mortality.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Xuan Ji, Weiqi Ke
Summary: This study examined the association between red blood cell distribution width (RDW) levels and all-cause mortality in congestive heart failure (CHF) patients. The findings suggested that higher RDW levels were associated with an increased risk of short-, medium-, and long-term all-cause death among CHF patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Environmental Sciences
Lei Yang, Fuyu Guo, Ning Wang, Shuo Liu, Xi Zhang, Huichao Li, Qingyu Li, Tao Xue, Qingyang Xiao, Xin Li, Hengyi Liu, Mingkun Tong, Pengfei Li, Aiguo Ren, Jiafu Ji
Summary: Urban greenness is positively associated with increased survival in lung cancer patients. Time-varying Cox models yield more conservative results compared to time-fixed models, showing a lower reduction in mortality rate with a 0.1-unit increment in both contemporaneous and cumulative average NDVI.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Public, Environmental & Occupational Health
Mahdi Nalini, Masoud Khoshnia, Farin Kamangar, Maryam Sharafkhah, Hossein Poustchi, Akram Pourshams, Gholamreza Roshandel, Samad Gharavi, Mahdi Zahedi, Alireza Norouzi, Masoud Sotoudeh, Arash Nikmanesh, Paul Brennan, Paolo Boffetta, Sanford M. Dawsey, Christian C. Abnet, Reza Malekzadeh, Arash Etemadi
Summary: This study investigated the joint effect of diabetes and opiate use on mortality, finding that individuals with both diabetes and opiate use had a significantly higher risk of all-cause mortality. The results highlight the importance of public awareness on the health effects of opiates and the need to improve diabetes care for individuals at risk of opiate use.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Infectious Diseases
Robert C. Ndege, James Okuma, Aneth Kalinjuma, Julius Mkumbo, Elizabeth Senkoro, Gideon Fue, Leila Samson, Herry Mapesi, Siraji Shabani, Tracy R. Glass, Manuel Battegay, Daniel H. Paris, Fiona Vanobberghen, Maja Weisser
Summary: The study revealed that failed pillbox return was associated with a higher risk of loss to follow-up among people living with HIV. Implementing simple interventions to identify these individuals could potentially reduce their chances of being lost to follow-up.
Article
Immunology
Josephine A. Muhairwe, Jennifer A. Brown, Lipontso Motaboli, Bienvenu L. Nsakala, Malebanye Lerotholi, Alain Amstutz, Thomas Klimkait, Tracy R. Glass, Niklaus D. Labhardt
Summary: Despite access to viral load monitoring, clinical management for children living with HIV in Lesotho was found to be suboptimal, with delays in follow-up viral load testing and treatment regimen switch.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Article
Surgery
Johanna C. F. Willburger, Marco von Strauss, Caspar J. Peterson, Tracy R. Glass, Christoph Kettelhack
Summary: This study investigated the incidence and outcomes of surgically treated retroperitoneal soft tissue sarcoma inpatients in Switzerland from 2005 to 2015. It found a clear trend of centralization of treatment in sarcoma centers, with higher complication rates but lower overall mortality rates for surgical-treated patients in these centers.
WORLD JOURNAL OF SURGERY
(2022)
Article
Infectious Diseases
Jennifer A. Brown, Bienvenu L. Nsakala, Kuena Mokhele, Itumeleng Rakuoane, Josephine Muhairwe, Tracy R. Glass, Alain Amstutz, Nadine Tschumi, Jennifer M. Belus, Thomas Klimkait, Niklaus D. Labhardt
Summary: The transition from EFV to DTG did not have negative impacts on the mental health and HIV/ART-related symptoms of people living with HIV, and potentially showed moderate improvements, supporting the rollout of DTG.
Letter
Biophysics
Mihaela Sava, Veronika Battig, Sabine Gerull, Jakob R. Passweg, Nina Khanna, Christian Garzoni, Bernhard Gerber, Nicolas J. Mueller, Urs Schanz, Christoph Berger, Yves Chalandon, Christian van Delden, Dionysios Neofytos, Susanne Stampf, Fabian C. Franzeck, Maja Weisser
BONE MARROW TRANSPLANTATION
(2023)
Article
Immunology
Anne-Valerie Burgener, Helena M. B. Seth-Smith, Sina Kern-Baumann, Ana Durovic, Anette Blaich, Thomas Menter, Elisabeth Bruder, Tim Roloff, Aurelien Martinez, Nicole Borel, Sarah Albini, Irene Hosli, Adrian Egli, Maja Weisser, Vladimira Hinic
Summary: Chlamydia abortus, the main cause of abortion in small ruminants, is often underestimated as a human pathogen. A case study in Switzerland involving a pregnant farmer with severe C. abortus infection highlights the diagnostic challenges and provides evidence of zoonotic transmission.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Immunology
Robert Ndege, Omary Ngome, Fiona Vanobberghen, Farida Bani, Yvan Temba, Herieth Wilson, Jerry Hella, Winfrid Gingo, Mohamed Sasamalo, Dorcas Mnzava, Namvua Kimera, Hellen Hiza, John Wigayi, Herry Mapesi, Irene B. Kato, Francis Mhimbira, Klaus Reither, Manuel Battegay, Daniel H. Paris, Maja Weisser, Martin Rohacek
Summary: In this randomized two-center trial, a diagnostic algorithm including Extended Focused Assessment with Sonography for Human Immunodeficiency Virus and Tuberculosis did not increase the proportion of correctly managed patients with suspected extrapulmonary tuberculosis versus control, but increased definite tuberculosis.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Immunology
Linda Stoeger, Andrew Katende, Herry Mapesi, Aneth Kalinjuma, Liselot van Essen, Thomas Klimkait, Manuel Battegay, Maja Weisser, Emilio Letang
Summary: Limited information is available about the burden, characteristics, predictors, and outcomes of advanced human immunodeficiency virus disease (AHD) in rural sub-Saharan Africa. This study found a high burden of AHD among people living with HIV in rural Tanzania, despite the implementation of the World Health Organization's guidelines. Over 50% of the participants still had AHD at the time of diagnosis.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Letter
Biophysics
Gioele Capoferri, Carla Simone Walti, Pascal Urwyler, Silvio Ragozzino, Jakob R. Passweg, Joerg Halter, Manuel Battegay, Veronika Baettig, Maja Weisser, Brice Arnold, Benedict Morin, Yukino Guetlin, Diana Albertos Torres, Gueliz Tuba Barut, Volker Thiel, Adrian Egli, Beatrice Drexler, Nina Khanna
BONE MARROW TRANSPLANTATION
(2023)
Article
Multidisciplinary Sciences
Lucas Romann, Laura Werlen, Nikki Rommers, Anja Hermann, Isabelle Gisler, Stefano Bassetti, Roland Bingisser, Martin Siegemund, Tim Roloff, Maja Weisser, Veronika C. Muigg, Vladimira Hinic, Michael Osthoff, Fabian Franzeck, Adrian Egli
Summary: This study evaluated factors for non-adherence to recommended blood culture volumes and assessed their effects on diagnostic performance. The use of central venous and arterial catheter for blood drawing resulted in increased filling volumes compared to peripheral venipuncture. Each additional nursing staff working at the time of blood drawing was associated with a higher likelihood of achieving the recommended filling volume. There was no significant correlation between the filling volume and the positivity rate.
Article
Multidisciplinary Sciences
Aneth Vedastus Kalinjuma, Hannah Hussey, Getrud Joseph Mollel, Emilio Letang, Manuel Battegay, Tracy R. Glass, Daniel Paris, Fiona Vanobberghen, Maja Weisser
Summary: Underweight and overweight/obesity are common health issues among people living with HIV (PLHIV) in rural sub-Saharan Africa, with underweight being associated with a higher risk of mortality and loss to follow-up.
Letter
Clinical Neurology
Florian Ebel, Sarah Tschudin-Sutter, Maja Weisser, Michel Roethlisberger
JOURNAL OF NEUROSURGERY
(2023)
Article
Surgery
F. Haak, O. Kollmar, A. Ioannidis, J. E. Slotta, M. B. Ghadimi, T. Glass, M. von Strauss Und Torney
Summary: This study retrospectively analyzed two cohorts from Switzerland and Germany, investigating the ability of clinical scoring systems and imaging to differentiate between complicated and uncomplicated appendicitis. Results showed limited capability of the current scoring systems to distinguish between complicated and uncomplicated appendicitis.
LANGENBECKS ARCHIVES OF SURGERY
(2022)