Virus inactivation at moderately low pH varies with virus and buffer properties

Physiochemical properties of enveloped viruses and arginine dictate inactivation

(2021) Christa L. Meingast et al.   Biotechnology Journal

Truly continuous low pH viral inactivation for biopharmaceutical process integration

(2020) Duarte L. Martins et al.   BIOTECHNOLOGY AND BIOENGINEERING

Viral contamination in biologic manufacture and implications for emerging therapies

(2020) Paul W. Barone et al.   NATURE BIOTECHNOLOGY

Suitability of a Generic Virus Safety Evaluation for Monoclonal Antibody Investigational New Drug Applications

(2019) Patrick Sipple et al.   BIOTECHNOLOGY PROGRESS

Arginine‐enveloped virus inactivation and potential mechanisms

(2019) Christa Meingast et al.   BIOTECHNOLOGY PROGRESS

Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization

(2019) Ruben Wälchli et al.   BIOTECHNOLOGY AND BIOENGINEERING

Virus Isoelectric Point Determination Using Single-Particle Chemical Force Microscopy

(2019) Xue Mi et al.   LANGMUIR

TrimethylamineN-oxide stabilizes proteins via a distinct mechanism compared with betaine and glycine

(2017) Yi-Ting Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of eco-friendly zwitterionic detergents for enveloped virus inactivation

(2016) Lynn Conley et al.   BIOTECHNOLOGY AND BIOENGINEERING

Adapting viral safety assurance strategies to continuous processing of biological products

(2016) Sarah A. Johnson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Characterization of operating parameters for XMuLV inactivation by low pH treatment

(2015) Shivanthi Chinniah et al.   BIOTECHNOLOGY PROGRESS

Controlling protein stability: Mechanisms revealed using formulations of arginine, glycine and guanidinium HCl with three globular proteins

(2015) Lauren Platts et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Structural analysis of herpes simplex virus by optical super-resolution imaging

(2015) Romain F. Laine et al.   Nature Communications

Equine arteritis virus

(2013) Udeni B.R. Balasuriya et al.   VETERINARY MICROBIOLOGY

Recovery and purification process development for monoclonal antibody production

(2010) Hui F. Liu et al.   mAbs

Virus inactivation by solvent/detergent treatment using Triton X-100 in a high purity factor VIII

(2008) Peter L. Roberts   BIOLOGICALS