Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells

Apitoxin and Its Components against Cancer, Neurodegeneration and Rheumatoid Arthritis: Limitations and Possibilities

(2020) Andreas Aufschnaiter et al.   Toxins

Venom-Derived Bioactive Compounds as Potential Anticancer Agents: A Review

(2020) Arpita Roy et al.   International Journal of Peptide Research and Therapeutics

Graviola leaves extract enhances the anticancer effect of cisplatin on various cancer cell lines

(2020) Mai G. Awad et al.   Molecular & Cellular Toxicology

Ruthenium(II)/(III) DMSO-Based Complexes of 2-Aminophenyl Benzimidazole with In Vitro and In Vivo Anticancer Activity

(2020) Shadia A. Elsayed et al.   MOLECULES

Melittin Exerts Beneficial Effects on Paraquat-Induced Lung Injuries In Mice by Modifying Oxidative Stress and Apoptosis

(2019) El-Aarag et al.   MOLECULES

Molecular mechanisms of natural compounds in cell death induction and sensitization to chemotherapeutic drugs in lung cancer

(2019) Onsurang Wattanathamsan et al.   PHYTOTHERAPY RESEARCH

Therapeutic Application of Diverse Marine-derived Natural Products in Cancer Therapy

(2019) CHUL WON YUN et al.   ANTICANCER RESEARCH

Bee Venom: Overview of Main Compounds and Bioactivities for Therapeutic Interests

(2019) Rim Wehbe et al.   MOLECULES

Bee Updated: Current Knowledge on Bee Venom and Bee Envenoming Therapy

(2019) Manuela B. Pucca et al.   Frontiers in Immunology

Redox-Mediated Mechanism of Chemoresistance in Cancer Cells

(2019) Eun-Kyung Kim et al.   Antioxidants

Hesperidin, piperine and bee venom synergistically potentiate the anticancer effect of tamoxifen against breast cancer cells

(2018) Abeer A.A. Khamis et al.   BIOMEDICINE & PHARMACOTHERAPY

Systemic therapy for intermediate and advanced hepatocellular carcinoma: Sorafenib and beyond

(2018) Jean-Luc Raoul et al.   CANCER TREATMENT REVIEWS

Bee venom therapy: Potential mechanisms and therapeutic applications

(2018) Shuai Zhang et al.   TOXICON

Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis

(2017) Daniela Sia et al.   GASTROENTEROLOGY

A novel melittin nano-liposome exerted excellent anti-hepatocellular carcinoma efficacy with better biological safety

(2017) Jie Mao et al.   Journal of Hematology & Oncology

Venom-based peptide therapy: insights into anti-cancer mechanism

(2017) Rui Ma et al.   Oncotarget

Therapeutic Properties of Bioactive Compounds from Different Honeybee Products

(2017) Laura Cornara et al.   Frontiers in Pharmacology

Antimicrobial peptide melittin against Xanthomonas oryzae pv. oryzae, the bacterial leaf blight pathogen in rice

(2016) Wei Shi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Application of bee venom and its main constituent melittin for cancer treatment

(2016) Cui-cui Liu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Anti-Inflammatory Applications of Melittin, a Major Component of Bee Venom: Detailed Mechanism of Action and Adverse Effects

(2016) Gihyun Lee et al.   MOLECULES

Treatment of hepatocellular carcinoma with portal venous tumor thrombosis: A comprehensive review

(2016) Kichang Han   WORLD JOURNAL OF GASTROENTEROLOGY

Development of sorafenib-related side effects in patients diagnosed with advanced hepatocellular carcinoma treated with sorafenib: a systematic-review and meta-analysis of the impact on survival

(2016) Omar Abdel-Rahman et al.   Expert Review of Gastroenterology & Hepatology

Novel combination of sorafenib and biochanin-A synergistically enhances the anti-proliferative and pro-apoptotic effects on hepatocellular carcinoma cells

(2016) Mohieldin M. Youssef  et al.   Scientific Reports

Sorafenib inhibits proliferation and invasion of human hepatocellular carcinoma cells via up-regulation of p53 and suppressing FoxM1

(2015) Ji-chao Wei et al.   ACTA PHARMACOLOGICA SINICA

Molecular Mechanism and Prediction of Sorafenib Chemoresistance in Human Hepatocellular Carcinoma

(2015) Naoshi Nishida et al.   DIGESTIVE DISEASES

Melittin suppresses cathepsin S-induced invasion and angiogenesis via blocking of the VEGF-A/VEGFR-2/MEK1/ERK1/2 pathway in human hepatocellular carcinoma

(2015) ZHI ZHANG et al.   Oncology Letters

Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction

(2014) Yosup Rew et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anti-genotoxicity and anti-mutagenicity of Apis mellifera venom

(2014) Márcia Miyuki Hoshina et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed by Biochemical Characterization

(2014) Kiyoshi Okamoto et al.   ACS Medicinal Chemistry Letters

Cytotoxicity of melittin and apamin in human hepatic L02 and HepG2 cellsin vitro

(2013) Jinhui Zhou et al.   Toxin Reviews

Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines

(2012) Fatima Rangwala et al.   BMC CANCER

Molecular mechanisms of sorafenib action in liver cancer cells

(2012) Melchiorre Cervello et al.   CELL CYCLE

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

(2011) Siwanon Jirawatnotai et al.   NATURE

Cytolytic peptide nanoparticles (‘NanoBees’) for cancer therapy

(2011) Hua Pan et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2

(2008) Federica Cossu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tetrahydroisoquinoline amide substituted phenyl pyrazoles as selective Bcl-2 inhibitors

(2008) John Porter et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway

(2008) Shujing Liu et al.   HEPATOLOGY