Discovery of clinical candidate Sivopixant (S-600918): Lead optimization of dioxotriazine derivatives as selective P2X3 receptor antagonists

Title
Discovery of clinical candidate Sivopixant (S-600918): Lead optimization of dioxotriazine derivatives as selective P2X3 receptor antagonists
Authors
Keywords
Purinergic receptors, Ion channels, P2X3 receptor antagonists, Dioxotriazine derivatives, Pain
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 52, Issue -, Pages 128384
Publisher
Elsevier BV
Online
2021-09-27
DOI
10.1016/j.bmcl.2021.128384

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