Synthesis and biological evaluation of novel PET tracers [18F]AG120 & [18F]AG135 for imaging mutant isocitrate dehydrogenase 1 expression
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synthesis and biological evaluation of novel PET tracers [18F]AG120 & [18F]AG135 for imaging mutant isocitrate dehydrogenase 1 expression
Authors
Keywords
F, PET imaging, Radiosynthesis, IDH1 mutation, IDH1 inhibitor
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 53, Issue -, Pages 116525
Publisher
Elsevier BV
Online
2021-11-28
DOI
10.1016/j.bmc.2021.116525
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- FDA Approval Summary: Ivosidenib for Relapsed or Refractory Acute Myeloid Leukemia with an Isocitrate Dehydrogenase-1 Mutation
- (2019) Kelly J. Norsworthy et al. CLINICAL CANCER RESEARCH
- Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors
- (2018) Satish K. Chitneni et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
- (2018) Songye Li et al. ACS Chemical Neuroscience
- Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular Signaling
- (2017) Laurence M. Gagné et al. TRENDS IN CELL BIOLOGY
- Sterol Regulatory Element Binding Protein Regulates the Expression and Metabolic Functions of Wild-Type and OncogenicIDH1
- (2016) Stéphane J. H. Ricoult et al. MOLECULAR AND CELLULAR BIOLOGY
- IDH1, a CHOP and C/EBPβ-responsive gene under ER stress, sensitizes human melanoma cells to hypoxia-induced apoptosis
- (2015) Xuejun Yang et al. CANCER LETTERS
- FOXOs support the metabolic requirements of normal and tumor cells by promoting IDH1 expression
- (2015) P. Charitou et al. EMBO REPORTS
- A General Copper-Mediated Nucleophilic18F Fluorination of Arenes
- (2014) Matthew Tredwell et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands
- (2014) Joël Mercier et al. ChemMedChem
- Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule
- (2014) Gejing Deng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 18F-Labeling Using Click Cycloadditions
- (2014) Kathrin Kettenbach et al. Biomed Research International
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping
- (2011) D. R. Borger et al. ONCOLOGIST
- Positron Emission Tomography (PET) Imaging with [11C]-Labeled Erlotinib: A Micro-PET Study on Mice with Lung Tumor Xenografts
- (2009) A. A. Memon et al. CANCER RESEARCH
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
- Fluorine in medicinal chemistry
- (2007) Sophie Purser et al. CHEMICAL SOCIETY REVIEWS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now