Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 144, Issue -, Pages -Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2021.112321
Keywords
Cancer; Magnetic nanoparticles; Therapeutic strategies; Advanced materials
Funding
- Shiraz University of Medical Sciences (Shiraz, Iran)
- Tabriz University of Medical Sciences (Tabriz, Iran)
- National Science Centre, Poland [UMO-2018/29/B/ST5/02412]
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Cancer poses a major challenge for biomedical basic research in contemporary times. Magnetite-based nanoparticles have garnered significant attention for cancer therapy due to their magnetic properties, multifunctional design, biodegradability, and biocompatibility. This review provides an overview of the applications of magnetic nanoparticles and recent advancements in utilizing these advanced materials for cancer therapy.
Cancer is one of the major challenges fronting the biomedical basic researches in our time. The study and development of effective therapeutic strategies for cancer therapy are vital. Among the many probable core constituents of nanoparticles, magnetite-based nanoparticles have been widely studied for cancer therapy owing to their inherent magnetic features, multifunctional design, biodegradable and biocompatible properties. Magnetic nanoparticles have been also designed for utilizing as contrast enhancer agents for magnetic resonance imaging, drug delivery systems, and most recently as a therapeutic element in inducing cellular death in tumor ablation therapies. This review aimed to provide an overview of the various applications of magnetic nano particles and recent achievements in developing these advanced materials for cancer therapy.
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