Cutting‐edge LC–MS/MS applications in clinical mass spectrometry: Focusing on analysis of drugs and metabolites

Simultaneous analysis of drugs administered to lung‐transplanted patients using liquid chromatography–tandem mass spectrometry for therapeutic drug monitoring

(2021) Shinya Takasaki et al.   BIOMEDICAL CHROMATOGRAPHY

Development of a simultaneous analytical method for clozapine and its metabolites in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry with linear range adjusted by in‐source collision‐induced dissociation

(2021) Toshihiro Sato et al.   BIOMEDICAL CHROMATOGRAPHY

Absolute quantitative analysis of endogenous neurotransmitters and amino acids by liquid chromatography-tandem mass spectrometry combined with multidimensional adsorption and collision energy defect

(2021) Jiajia Shen et al.   JOURNAL OF CHROMATOGRAPHY A

High‐throughput liquid chromatography/electrospray ionization–tandem mass spectrometry method using in‐source collision‐induced dissociation for simultaneous quantification of imatinib, dasatinib, bosutinib, nilotinib, and ibrutinib in human plasma

(2021) Tensei Hirasawa et al.   BIOMEDICAL CHROMATOGRAPHY

Establishment of an analytical method for simultaneous quantitation of CDK4/6 inhibitors, aromatase inhibitors, and an estrogen receptor antagonist in human plasma using LC-ESI-MS/MS

(2021) Yu Sato et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Fully Automated Quantitative Measurement of Serum Organic Acids via LC-MS/MS for the Diagnosis of Organic Acidemias: Establishment of an Automation System and a Proof-of-Concept Validation

(2021) Yasushi Ueyanagi et al.   Diagnostics

A lipidome atlas in MS-DIAL 4

(2020) Hiroshi Tsugawa et al.   NATURE BIOTECHNOLOGY

Development of a Diagnostic Screening Strategy for Niemann–Pick Diseases Based on Simultaneous Liquid Chromatography-Tandem Mass Spectrometry Analyses of N-Palmitoyl-O-phosphocholine-serine and Sphingosylphosphorylcholine

(2020) Anna Iwahori et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Structural Determination of Lysosphingomyelin-509 and Discovery of Novel Class Lipids from Patients with Niemann–Pick Disease Type C

(2019) Maekawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Investigation of diagnostic performance of five urinary cholesterol metabolites for Niemann-Pick disease type C

(2019) Masamitsu Maekawa et al.   JOURNAL OF LIPID RESEARCH

Simultaneous analysis of oral anticancer drugs for renal cell carcinoma in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry

(2018) Shinya Takasaki et al.   BIOMEDICAL CHROMATOGRAPHY

Relationships between sunitinib plasma concentration and clinical outcomes in Japanese patients with metastatic renal cell carcinoma

(2018) Shinya Takasaki et al.   International Journal of Clinical Oncology

Quantitative structural multiclass lipidomics using differential mobility: electron impact excitation of ions from organics (EIEIO) mass spectrometry

(2018) Takashi Baba et al.   JOURNAL OF LIPID RESEARCH

Consensus clinical management guidelines for Niemann-Pick disease type C

(2018) Tarekegn Geberhiwot et al.   Orphanet Journal of Rare Diseases

The impact of biomarkers analysis in the diagnosis of Niemann-Pick C disease and acid sphingomyelinase deficiency

(2018) Federica Deodato et al.   CLINICA CHIMICA ACTA

A simple and fast HPLC-MS/MS method for simultaneous determination of direct oral anticoagulants apixaban, dabigatran, rivaroxaban in human plasma

(2018) Jennifer Lagoutte-Renosi et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Hydrogen Attachment/Abstraction Dissociation (HAD) of Gas-Phase Peptide Ions for Tandem Mass Spectrometry

(2016) Hidenori Takahashi et al.   ANALYTICAL CHEMISTRY

A simultaneous determination method for 5-fluorouracil and its metabolites in human plasma with linear range adjusted by in-source collision-induced dissociation using hydrophilic interaction liquid chromatography-electrospray ionization-tandem mass spect

(2016) Hideaki Ishii et al.   BIOMEDICAL CHROMATOGRAPHY

Shifting the Linear Range in Electrospray Ionization by In-Source Collision-Induced Dissociation

(2016) Hideaki Ishii et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Identification of novel bile acids as biomarkers for the early diagnosis of Niemann-Pick C disease

(2016) Francesca Mazzacuva et al.   FEBS LETTERS

Development of a bile acid–based newborn screen for Niemann-Pick disease type C

(2016) Xuntian Jiang et al.   Science Translational Medicine

A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease

(2015) Anne-Katrin Giese et al.   Orphanet Journal of Rare Diseases

Focused metabolomics using liquid chromatography/electrospray ionization tandem mass spectrometry for analysis of urinary conjugated cholesterol metabolites from patients with Niemann–Pick disease type C and 3β-hydroxysteroid dehydrogenase deficiency

(2015) Masamitsu Maekawa et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Plasma Lysosphingomyelin Demonstrates Great Potential as a Diagnostic Biomarker for Niemann-Pick Disease Type C in a Retrospective Study

(2014) Richard W. D. Welford et al.   PLoS One

Determination of 7-ketocholesterol in plasma by LC-MS for rapid diagnosis of acid SMase-deficient Niemann-Pick disease

(2013) Na Lin et al.   JOURNAL OF LIPID RESEARCH

LC/ESI-MS/MS analysis of urinary 3β-sulfooxy-7β-N-acetylglucosaminyl-5-cholen-24-oic acid and its amides: New biomarkers for the detection of Niemann–Pick type C disease

(2013) Masamitsu Maekawa et al.   STEROIDS

Tandem mass spectrometric characterization of bile acids and steroid conjugates based on low-energy collision-induced dissociation

(2013) Masamitsu Maekawa et al.   STEROIDS

A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma

(2011) Xuntian Jiang et al.   JOURNAL OF LIPID RESEARCH

Expanding the linear dynamic range for multiple reaction monitoring in quantitative liquid chromatography–tandem mass spectrometry utilizing natural isotopologue transitions

(2011) Hanghui Liu et al.   TALANTA

Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease

(2010) F. D. Porter et al.   Science Translational Medicine