Targeting the Oxytocin System to Ameliorate Early Life Depressive-Like Behaviors in Maternally-Separated Rats

Anxiety-like behaviour assessments of adolescent rats after repeated maternal separation during early life

(2018) Shengtao Jin et al.   NEUROREPORT

The Oxytocin Receptor: From Intracellular Signaling to Behavior

(2018) Benjamin Jurek et al.   PHYSIOLOGICAL REVIEWS

Potential therapeutic role of melatonin on STZ-induced diabetic central neuropathy: A biochemical, histopathological, immunohistochemical and ultrastructural study

(2018) Mohamed M.M. Metwally et al.   ACTA HISTOCHEMICA

Early Life Stress in Rodents: Animal Models of Illness or Resilience?

(2018) Sahana Murthy et al.   Frontiers in Behavioral Neuroscience

Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons

(2017) Yu-Ting Lin et al.   Nature Communications

Maternal separation activates microglial cells and induces an inflammatory response in the hippocampus of male rat pups, independently of hypothalamic and peripheral cytokine levels

(2016) Angélica Roque et al.   BRAIN BEHAVIOR AND IMMUNITY

Effect of selective serotonin reuptake inhibitors on expression of 5-HT1AR and neurotransmitters in rats with vascular dementia

(2016) K. Guo et al.   GENETICS AND MOLECULAR RESEARCH

Carbetocin is a Functional Selective Gq Agonist That Does Not Promote Oxytocin Receptor Recycling After Inducing β-Arrestin-Independent Internalisation

(2016) I. Passoni et al.   JOURNAL OF NEUROENDOCRINOLOGY

Efficacy and safety of carbetocin applied as an intravenous bolus compared to as a short-infusion for caesarean section: study protocol for a randomised controlled trial

(2016) Salome Dell-Kuster et al.   Trials

Paeoniflorin ameliorates interferon-alpha-induced neuroinflammation and depressive-like behaviors in mice

(2016) Jianwei Li et al.   Oncotarget

Additional intranasal oxytocin to escitalopram improves depressive symptoms in resistant depression: An open trial

(2015) G. Scantamburlo et al.   EUROPEAN PSYCHIATRY

Changed Synaptic Plasticity in Neural Circuits of Depressive-Like and Escitalopram-Treated Rats

(2015) Xiao-Li Li et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Activation of presynaptic oxytocin receptors enhances glutamate release in the ventral hippocampus of prenatally restraint stressed rats

(2015) Jérôme Mairesse et al.   PSYCHONEUROENDOCRINOLOGY

Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation

(2015) Paul J. Lucassen et al.   Cold Spring Harbor Perspectives in Biology

The Effects of Oxytocin on Cognitive Defect Caused by Chronic Restraint Stress Applied to Adolescent Rats and on Hippocampal VEGF and BDNF Levels

(2015) Nazan Uysal   MEDICAL SCIENCE MONITOR

Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice

(2015) Yaoyao Bian et al.   NEURAL PLASTICITY

Switching brain serotonin with oxytocin

(2014) R. Mottolese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neonatal maternal separation up-regulates protein signalling for cell survival in rat hypothalamus

(2014) Claudine Irles et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

(2013) Grazyna Rajkowska et al.   CURRENT DRUG TARGETS

Effect of escitalopram on cardiomyopathy-induced anxiety in mice

(2013) M. J. Anwar et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Prior cold water swim stress alters immobility in the forced swim test and associated activation of serotonergic neurons in the rat dorsal raphe nucleus

(2013) R.C. Drugan et al.   NEUROSCIENCE

Multiple Roles for Astrocytes as Effectors of Cytokines and Inflammatory Mediators

(2013) Michael V. Sofroniew   NEUROSCIENTIST

Early-life stress has persistent effects on amygdala function and development in mice and humans

(2013) M. Malter Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation

(2013) D. G. Gee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Oxytocin in Psychiatric Disorders

(2013) David M. Cochran et al.   HARVARD REVIEW OF PSYCHIATRY

Comparison of neuroprotective effects of five major lipophilic diterpenoids from Danshen extract against experimentally induced transient cerebral ischemic damage

(2012) Ok Kyu Park et al.   FITOTERAPIA

Maternal separation and proclivity for ethanol intake: A potential role of the endocannabinoid system in rats

(2012) A. Romano-López et al.   NEUROSCIENCE

Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala

(2012) Elizabeth I. Flandreau et al.   PSYCHONEUROENDOCRINOLOGY

Cortisol-Induced Increases of Plasma Oxytocin Levels Predict Decreased Immediate Free Recall of Unpleasant Words

(2012) Mattie Tops et al.   Frontiers in Psychiatry

Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids

(2011) Benedetta Leuner et al.   HIPPOCAMPUS

Lifetime Prevalence of Mental Disorders in U.S. Adolescents: Results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A)

(2011) Kathleen Ries Merikangas et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Astrocytic Hypertrophy in Anterior Cingulate White Matter of Depressed Suicides

(2011) Susana G Torres-Platas et al.   NEUROPSYCHOPHARMACOLOGY

Escitalopram and Neuroendocrine Response in Healthy First-Degree Relatives to Depressed Patients – A Randomized Placebo-Controlled Trial

(2011) Ulla Knorr et al.   PLoS One

Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats

(2010) Henriëtte J. Hulshof et al.   BEHAVIOURAL BRAIN RESEARCH

Preliminary evidence that plasma oxytocin levels are elevated in major depression

(2010) Karen J. Parker et al.   PSYCHIATRY RESEARCH

Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test

(2010) Stella Chaviaras et al.   PSYCHOPHARMACOLOGY

Intracellular trafficking of the human oxytocin receptor: evidence of receptor recycling via a Rab4/Rab5 “short cycle”

(2009) Francesca Conti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Astrocytic Plasticity and Patterned Oxytocin Neuronal Activity: Dynamic Interactions

(2009) Y.-F. Wang et al.   JOURNAL OF NEUROSCIENCE

Evidence That Oxytocin Exerts Anxiolytic Effects via Oxytocin Receptor Expressed in Serotonergic Neurons in Mice

(2009) M. Yoshida et al.   JOURNAL OF NEUROSCIENCE

Maternal separation interferes with developmental changes in brain vasopressin and oxytocin receptor binding in male rats

(2009) M. Lukas et al.   NEUROPHARMACOLOGY

Serum oxytocin levels in patients with depression and the effects of gender and antidepressant treatment

(2009) Saliha Ozsoy et al.   PSYCHIATRY RESEARCH

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression

(2008) Michael Maes et al.   METABOLIC BRAIN DISEASE

Influence of escitalopram treatment on 5-HT1A receptor binding in limbic regions in patients with anxiety disorders

(2008) C Spindelegger et al.   MOLECULAR PSYCHIATRY

Maternal separation of rat pups increases the risk of developing depressive-like behavior after subsequent chronic stress by altering corticosterone and neurotrophin levels in the hippocampus

(2008) Lelanie Marais et al.   NEUROSCIENCE RESEARCH