Autophagy deficiency activates rDNA transcription

mTOR at the nexus of nutrition, growth, ageing and disease

(2020) Grace Y. Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acetylation of STX17 (syntaxin 17) controls autophagosome maturation

(2020) Qiuhong Shen et al.   Autophagy

A role for the autophagic receptor, SQSTM1/p62, in trafficking NF-κB/RelA to nucleolar aggresomes

(2020) Ian T Lobb et al.   MOLECULAR CANCER RESEARCH

Autophagy in Human Diseases

(2020) Noboru Mizushima et al.   NEW ENGLAND JOURNAL OF MEDICINE

LC3-associated phagocytosis at a glance

(2019) Bradlee L. Heckmann et al.   JOURNAL OF CELL SCIENCE

p62 functions as an oncogene in colorectal cancer through inhibiting apoptosis and promoting cell proliferation by interacting with the vitamin D receptor

(2019) Jing Zhang et al.   CELL PROLIFERATION

Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress

(2019) Zhiyuan You et al.   Nature Communications

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

(2018) Gregory A. Wyant et al.   SCIENCE

mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux

(2018) Wei Wan et al.   MOLECULAR CELL

mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis

(2017) Wei Wan et al.   MOLECULAR CELL

Systematic analysis of ribophagy in human cells reveals bystander flux during selective autophagy

(2017) Heeseon An et al.   NATURE CELL BIOLOGY

Poly(A) tail length regulates PABPC1 expression to tune translation in the heart

(2017) Sandip Chorghade et al.   eLife

TP53INP2/DOR, a mediator of cell autophagy, promotes rDNA transcription via facilitating the assembly of the POLR1/RNA polymerase I preinitiation complex at rDNA promoters

(2016) Yinfeng Xu et al.   Autophagy

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

Duration of the first steps of the human rRNA processing

(2013) Alexey Popov et al.   Nucleus

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

(2012) N. Jaber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes

(2011) Chi Kwan Tsang et al.   CELL CYCLE

mTOR signaling in disease

(2011) Eva Dazert et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

(2011) Yoshihiro Inami et al.   JOURNAL OF CELL BIOLOGY

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

(2011) Angeles Duran et al.   MOLECULAR CELL

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer

(2010) Denis Drygin et al.   Annual Review of Pharmacology and Toxicology

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique

(2010) Craig A. Goodman et al.   FASEB JOURNAL

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

(2009) S. Hoppe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis

(2008) Angeles Duran et al.   CANCER CELL

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY

RNA polymerases I and III, non-coding RNAs and cancer

(2008) Robert J. White   TRENDS IN GENETICS