Simultaneous Detection of Herpes Simplex Virus Type 1 Latent and Lytic Transcripts in Brain Tissue

Human Herpesvirus 6 Detection in Alzheimer’s Disease Cases and Controls across Multiple Cohorts

(2020) Mary Alice Allnutt et al.   NEURON

Reanalysis of Alzheimer's Brain Sequencing Data Reveals Absence of Purported HHV6A and HHV7

(2020) Samuel D. Chorlton   Journal of Bioinformatics and Computational Biology

HSV-1 infection and pathogenesis in the tree shrew eye following corneal inoculation

(2020) Lihong Li et al.   JOURNAL OF NEUROVIROLOGY

Herpes Simplex Virus-1 in the Brain: The Dark Side of a Sneaky Infection

(2020) Maria Elena Marcocci et al.   TRENDS IN MICROBIOLOGY

Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis

(2020) Jean-Pierre Roussarie et al.   NEURON

Infectious herpes simplex virus in the brainstem is correlated with reactivation in the trigeminal ganglia

(2019) Jessica R. Doll et al.   JOURNAL OF VIROLOGY

Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome

(2019) Yun-Tao Liu et al.   NATURE

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

(2019) John V. Pluvinage et al.   NATURE

The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques

(2019) Carlo Sala Frigerio et al.   Cell Reports

The viral protein corona directs viral pathogenesis and amyloid aggregation

(2019) Kariem Ezzat et al.   Nature Communications

Persistent Toll-like receptor 7 stimulation induces behavioral and molecular innate immune tolerance

(2019) Katherine A. Michaelis et al.   BRAIN BEHAVIOR AND IMMUNITY

Single-Cell Quantification of mRNA Expression in The Human Brain

(2019) Sarah Jolly et al.   Scientific Reports

Strategies for Success. Viral Infections and Membraneless Organelles

(2019) Aracelly Gaete-Argel et al.   Frontiers in Cellular and Infection Microbiology

A Combination of Ontogeny and CNS Environment Establishes Microglial Identity

(2018) F. Chris Bennett et al.   NEURON

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

(2018) William A. Eimer et al.   NEURON

Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

(2018) Ben Readhead et al.   NEURON

Glial- and Neuronal-Specific Expression of CCL5 mRNA in the Rat Brain

(2018) Maria Fe Lanfranco et al.   Frontiers in Neuroanatomy

Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication

(2018) Junjie Zhang et al.   Cell Host & Microbe

Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells

(2017) Chandra M. Menendez et al.   Journal of Neuroinflammation

Role of neuroinflammation in neurodegeneration: new insights

(2017) Róisín M. McManus et al.   Alzheimers Research & Therapy

Anti-Viral Properties of Amyloid-β Peptides

(2016) Karine Bourgade et al.   JOURNAL OF ALZHEIMERS DISEASE

Microbes and Alzheimer’s Disease

(2016) Ruth F. Itzhaki et al.   JOURNAL OF ALZHEIMERS DISEASE

Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency

(2016) Chandra M. Menendez et al.   JOURNAL OF IMMUNOLOGY

The HSV-1 Latency-Associated Transcript Functions to Repress Latent Phase Lytic Gene Expression and Suppress Virus Reactivation from Latently Infected Neurons

(2016) Michael P. Nicoll et al.   PLoS Pathogens

Analysis of the brain mural cell transcriptome

(2016) Liqun He et al.   Scientific Reports

Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis

(2015) Sidi Chen et al.   CELL

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Normalization of Reverse Transcription Quantitative PCR Data During Ageing in Distinct Cerebral Structures

(2015) G. Bruckert et al.   MOLECULAR NEUROBIOLOGY

A Method for Combining RNAscope In Situ Hybridization with Immunohistochemistry in Thick Free-Floating Brain Sections and Primary Neuronal Cultures

(2015) Tessa M. Grabinski et al.   PLoS One

Detection of viral pathogens in high grade gliomas from unmapped next-generation sequencing data

(2014) Patrick J. Cimino et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Medroxyprogesterone Acetate Inhibits CD8+ T Cell Viral-Specific Effector Function and Induces Herpes Simplex Virus Type 1 Reactivation

(2014) T. L. Cherpes et al.   JOURNAL OF IMMUNOLOGY

In Vivo Reactivation of Latent Herpes Simplex Virus 1 in Mice Can Occur in the Brain before Occurring in the Trigeminal Ganglion

(2014) H.-W. Yao et al.   JOURNAL OF VIROLOGY

Light Microscopy, Culture, Molecular, and Serologic Methods for Detection of Herpes Simplex Virus

(2013) N. W. Anderson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Infectious burden and cognitive function: The Northern Manhattan Study

(2013) M. Katan et al.   NEUROLOGY

Development and Comparison of a Rapid Isothermal Nucleic Acid Amplification Test for Typing of Herpes Simplex Virus Types 1 and 2 on a Portable Fluorescence Detector

(2012) Yanhong Tong et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Herpes simplex virus type 1 induces nuclear accumulation of hyperphosphorylated tau in neuronal cells

(2012) Gema Álvarez et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A cultured affair: HSV latency and reactivation in neurons

(2012) Angus C. Wilson et al.   TRENDS IN MICROBIOLOGY

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Herpes simplex virus type I induces the accumulation of intracellular β-amyloid in autophagic compartments and the inhibition of the non-amyloidogenic pathway in human neuroblastoma cells

(2011) Soraya Santana et al.   NEUROBIOLOGY OF AGING

APP Processing Induced by Herpes Simplex Virus Type 1 (HSV-1) Yields Several APP Fragments in Human and Rat Neuronal Cells

(2010) Giovanna De Chiara et al.   PLoS One

Identification of a novel herpes simplex virus type 1 transcript and protein (AL3) expressed during latency

(2009) T. Jaber et al.   JOURNAL OF GENERAL VIROLOGY

Comparison of intravenous versus intraperitoneal administration of oncolytic herpes simplex virus 1 for peritoneal carcinomatosis in mice

(2008) Y Kulu et al.   CANCER GENE THERAPY

Attenuated multimutated herpes simplex virus-1 effectively treats prostate carcinomas with neural invasion while preserving nerve function

(2008) Kaitlyn Kelly et al.   FASEB JOURNAL

Clinical Validation of a New Triplex Real-Time Polymerase Chain Reaction Assay for the Detection and Discrimination of Herpes simplex Virus Types 1 and 2

(2008) Heide Reil et al.   JOURNAL OF MOLECULAR DIAGNOSTICS