Potency of Omadacycline against Mycobacteroides abscessus Clinical Isolates In Vitro and in a Mouse Model of Pulmonary Infection

Preliminary, Real-World, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections

(2021) Taylor Morrisette et al.   Open Forum Infectious Diseases

Treatment of Mycobacterium abscessus Pulmonary Disease

(2021) David E. Griffith et al.   CHEST

Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent

(2020) George G. Zhanel et al.   DRUGS

A mouse model of pulmonary Mycobacteroides abscessus infection

(2020) Emily C. Maggioncalda et al.   Scientific Reports

Efficacy of Bedaquiline, Alone or in Combination with Imipenem, against Mycobacterium abscessus in C3HeB/FeJ Mice

(2020) Vincent Le Moigne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Minimal Inhibitory Concentration of Clofazimine among Clinical Isolates of Nontuberculous Mycobacteria and Its Impact on Treatment Outcome

(2020) Nakwon Kwak et al.   CHEST

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline: Executive Summary

(2020) Charles L Daley et al.   CLINICAL INFECTIOUS DISEASES

Omadacycline for the Treatment of Mycobacterium abscessus Disease: A Case Series

(2020) Jeffrey C Pearson et al.   Open Forum Infectious Diseases

In Vitro Susceptibility Testing of Omadacycline against Nontuberculous Mycobacteria (NTM)

(2020) Barbara A. Brown-Elliott et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro susceptibility of Mycobacterium abscessus complex and feasibility of standardizing treatment regimens

(2020) Ka Lip Chew et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vitro pharmacodynamics of omadacycline against Escherichia coli and Acinetobacter baumannii

(2020) A R Noel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Omadacycline for Community-Acquired Bacterial Pneumonia

(2019) Roman Stets et al.   NEW ENGLAND JOURNAL OF MEDICINE

Omadacycline for Acute Bacterial Skin and Skin-Structure Infections

(2019) William O’Riordan et al.   NEW ENGLAND JOURNAL OF MEDICINE

In vitro activities of omadacycline against rapidly growing mycobacteria

(2019) Carolyn Shoen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vivo Pharmacodynamics of Omadacycline against Staphylococcus aureus in the Neutropenic Murine Thigh Infection Model

(2019) Alexander J. Lepak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of New Tetracycline Analogs Omadacycline and Eravacycline against Drug-Resistant Clinical Isolates of Mycobacterium abscessus

(2019) Amit Kaushik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Omadacycline as a promising new agent for the treatment of infections with Mycobacterium abscessus

(2019) Hannelore I Bax et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In Vivo Pharmacodynamic Evaluation of Omadacycline against Staphylococcus aureus in the Neutropenic Mouse Pneumonia Model

(2019) Alexander J. Lepak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Omadacycline in the Treatment of Mycobacterium abscessus Infection

(2019) Miguel G Madariaga   CLINICAL INFECTIOUS DISEASES

Once-daily oral omadacycline versus twice-daily oral linezolid for acute bacterial skin and skin structure infections (OASIS-2): a phase 3, double-blind, multicentre, randomised, controlled, non-inferiority trial

(2019) William O'Riordan et al.   LANCET INFECTIOUS DISEASES

Assessment of Clofazimine and TB47 Combination Activity against Mycobacterium abscessus Using a Bioluminescent Approach

(2019) Yang Liu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Repurposing drugs for treatment of Mycobacterium abscessus: a view to a kill

(2019) Tawanda Gumbo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Intraperitoneal Route of Drug Administration: Should it Be Used in Experimental Animal Studies?

(2019) Abdullah Al Shoyaib et al.   PHARMACEUTICAL RESEARCH

Activities of Dual Combinations of Antibiotics Against Multidrug-Resistant Nontuberculous Mycobacteria Recovered from Patients with Cystic Fibrosis

(2018) Matthew Schwartz et al.   Microbial Drug Resistance

Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera

(2018) Radhey S. Gupta et al.   Frontiers in Microbiology

A bedaquiline/clofazimine combination regimen might add activity to the treatment of clinically relevant non-tuberculous mycobacteria

(2018) Mike Marvin Ruth et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD)

(2017) Charles S Haworth et al.   THORAX

US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis

(2016) Patrick A. Flume   Journal of Cystic Fibrosis

The antimicrobial susceptibility of non-tuberculous mycobacteria

(2016) S. Cowman et al.   JOURNAL OF INFECTION

Characterization of Mouse Models of Mycobacterium avium Complex Infection and Evaluation of Drug Combinations

(2015) Claire Andréjak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Susceptibility of Mycobacterium abscessus to Antimycobacterial Drugs in Preclinical Models

(2015) Andrés Obregón-Henao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Epidemiology of Human Pulmonary Infection with Nontuberculous Mycobacteria

(2015) D. Rebecca Prevots et al.   CLINICS IN CHEST MEDICINE

US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis

(2015) R Andres Floto et al.   THORAX

Clinical experience in 52 patients with tigecycline-containing regimens for salvage treatment of Mycobacterium abscessus and Mycobacterium chelonae infections

(2014) R. J. Wallace et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In VitroandIn VivoAntibacterial Activities of Omadacycline, a Novel Aminomethylcycline

(2013) A. B. Macone et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanism of Action of the Novel Aminomethylcycline Antibiotic Omadacycline

(2013) Michael P. Draper et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vivo Evaluation of Antibiotic Activity Against Mycobacterium abscessus

(2013) Isabelle Lerat et al.   JOURNAL OF INFECTIOUS DISEASES

A Randomized, Evaluator-Blind, Phase 2 Study Comparing the Safety and Efficacy of Omadacycline to Those of Linezolid for Treatment of Complicated Skin and Skin Structure Infections

(2012) Gary J. Noel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroSynergy between Clofazimine and Amikacin in Treatment of Nontuberculous Mycobacterial Disease

(2012) Jakko van Ingen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance mechanisms and drug susceptibility testing of nontuberculous mycobacteria

(2012) Jakko van Ingen et al.   DRUG RESISTANCE UPDATES

Mycobacterium abscessus: a new antibiotic nightmare

(2012) R. Nessar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Clinical and Microbiologic Outcomes in Patients Receiving Treatment for Mycobacterium abscessus Pulmonary Disease

(2011) Julie Jarand et al.   CLINICAL INFECTIOUS DISEASES

Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice

(2011) Deepak Almeida et al.   PLoS Neglected Tropical Diseases

Comparative Studies Evaluating Mouse Models Used for Efficacy Testing of Experimental Drugs againstMycobacterium tuberculosis

(2010) Mary A. De Groote et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiotic Treatment ofMycobacterium abscessusLung Disease

(2009) Kyeongman Jeon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE