Identification of in vitro JMJD lysine demethylase candidate substrates via systematic determination of substrate preference

Proteome-wide Prediction of Lysine Methylation Leads to Identification of H2BK43 Methylation and Outlines the Potential Methyllysine Proteome

(2020) Kyle K. Biggar et al.   Cell Reports

Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling

(2019) James E. Longbotham et al.   Nature Communications

PeSA: A software tool for peptide specificity analysis

(2019) Emine Topcu et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Targeting histone demethylases KDM5A and KDM5B in AML cancer cells: A comparative view

(2018) Gelareh Shokri et al.   LEUKEMIA RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

(2018) Evan M. Cornett et al.   Science Advances

Methyllysine binding domains: Structural insight and small molecule probe development

(2017) Kelly A. Teske et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A charge-suppressing strategy for probing protein methylation

(2016) Zhibin Ning et al.   CHEMICAL COMMUNICATIONS

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

(2016) Maia Vinogradova et al.   Nature Chemical Biology

Epigenetics and Human Disease

(2016) Huda Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases

(2015) John R. Horton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-throughput screening to identify inhibitors of lysine demethylases

(2015) Molly Gale et al.   Epigenomics

Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism

(2015) Idelisse Ortiz Torres et al.   Nature Communications

Role of MTA1 in cancer progression and metastasis

(2014) Nirmalya Sen et al.   CANCER AND METASTASIS REVIEWS

The KDM5 family of histone demethylases as targets in oncology drug discovery

(2014) Peter Birk Rasmussen et al.   Epigenomics

Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis

(2014) Jian Cao et al.   Cell Reports

A Core Chromatin Remodeling Factor Instructs Global Chromatin Signaling through Multivalent Reading of Nucleosome Codes

(2013) Sujit S. Nair et al.   MOLECULAR CELL

Proteome-wide enrichment of proteins modified by lysine methylation

(2013) Scott M Carlson et al.   Nature Protocols

Chemical and biochemical approaches in the study of histone methylation and demethylation

(2012) Keqin Kathy Li et al.   MEDICINAL RESEARCH REVIEWS

Epigenetic protein families: a new frontier for drug discovery

(2012) Cheryl H. Arrowsmith et al.   NATURE REVIEWS DRUG DISCOVERY

Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay

(2011) Matthew Plant et al.   ANALYTICAL BIOCHEMISTRY

Studying protein–protein interactions using peptide arrays

(2011) Chen Katz et al.   CHEMICAL SOCIETY REVIEWS

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

(2011) Lauren P. Blair et al.   Cancers

Development of homogeneous luminescence assays for histone demethylase catalysis and binding

(2010) Akane Kawamura et al.   ANALYTICAL BIOCHEMISTRY

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

(2010) Nima Mosammaparast et al.   Annual Review of Biochemistry

Structural insights into histone lysine demethylation

(2010) Haifeng Hou et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Combinatorial profiling of chromatin binding modules reveals multisite discrimination

(2010) Adam L Garske et al.   Nature Chemical Biology

A gateway to study protein lysine methylation

(2008) Patrick Trojer et al.   Nature Chemical Biology

Repression of Smad3 activity by histone demethylase SMCX/JARID1C

(2007) Tae-Dong Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS