Mitochondrial redox regulation and myocardial ischemia-reperfusion injury

Reperfusion mediates heme impairment with increased protein cysteine sulfonation of mitochondrial complex III in the post-ischemic heart

(2021) Chwen-Lih Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

(2019) Jasmina Zivanovic et al.   Cell Metabolism

Mitochondrial complex I in the post-ischemic heart reperfusion-mediated oxidative injury and protein cysteine sulfonation

(2018) Patrick T. Kang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential protein acetylation assists import of excess SOD2 into mitochondria and mediates SOD2 aggregation associated with cardiac hypertrophy in the murine SOD2-tg heart

(2017) Liwen Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structure of bacterial respiratory complex I

(2016) John M. Berrisford et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structure of mammalian respiratory complex I

(2016) Jiapeng Zhu et al.   NATURE

Atomic structure of the entire mammalian mitochondrial complex I

(2016) Karol Fiedorczuk et al.   NATURE

Increased mitochondrial prooxidant activity mediates up-regulation of Complex I S-glutathionylation via protein thiyl radical in the murine heart of eNOS−/−

(2015) Patrick T. Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Overexpressing superoxide dismutase 2 induces a supernormal cardiac function by enhancing redox-dependent mitochondrial function and metabolic dilation

(2015) Patrick T. Kang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

BCNU-induced gR2 DEFECT mediates S-glutathionylation of Complex I and respiratory uncoupling in myocardium

(2014) Patrick T. Kang et al.   BIOCHEMICAL PHARMACOLOGY

Characterisation of the active/de-active transition of mitochondrial complex I

(2014) Marion Babot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cardiac Mitochondria and Reactive Oxygen Species Generation

(2014) Yeong-Renn Chen et al.   CIRCULATION RESEARCH

Conformational Change of Mitochondrial Complex I Increases ROS Sensitivity During Ischemia

(2013) Natalia Gorenkova et al.   ANTIOXIDANTS & REDOX SIGNALING

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Crystal structure of the entire respiratory complex I

(2013) Rozbeh Baradaran et al.   NATURE

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

(2013) Edward T Chouchani et al.   NATURE MEDICINE

Real-time monitoring of superoxide accumulation and antioxidant activity in a brain slice model using an electrochemical cytochrome c biosensor

(2012) Mallikarjunarao Ganesana et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein thiyl radical mediates S-glutathionylation of complex I

(2012) Patrick T. Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Myristoylated methionine sulfoxide reductase A protects the heart from ischemia-reperfusion injury

(2011) Hang Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Characterization of potential S-nitrosylation sites in the myocardium

(2011) Mark J. Kohr et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Understanding mitochondrial complex I assembly in health and disease

(2011) Masakazu Mimaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

H 2 O 2 -Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca 2+ -Activated K + Channel Activation

(2011) David X. Zhang et al.   CIRCULATION RESEARCH

New insights into the superoxide generation sites in bovine heart NADH-ubiquinone oxidoreductase (Complex I): The significance of protein-associated ubiquinone and the dynamic shifting of generation sites between semiflavin and semiquinone radicals

(2010) S. Tsuyoshi Ohnishi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Simultaneous Measurement of Protein Oxidation and S -Nitrosylation During Preconditioning and Ischemia/Reperfusion Injury With Resin-Assisted Capture

(2010) Mark J. Kohr et al.   CIRCULATION RESEARCH

Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging

(2009) Dao-Fu Dai et al.   CIRCULATION

Peptide-based Antibodies against Glutathione-binding Domains Suppress Superoxide Production Mediated by Mitochondrial Complex I

(2009) Jingfeng Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: Mitochondria as the major target

(2008) Bin Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Compensatory Growth of Healthy Cardiac Cells in the Presence of Diseased Cells Restores Tissue Homeostasis during Heart Development

(2008) Jörg-Detlef Drenckhahn et al.   DEVELOPMENTAL CELL

Protein Tyrosine Nitration of the Flavin Subunit Is Associated with Oxidative Modification of Mitochondrial Complex II in the Post-ischemic Myocardium

(2008) Chwen-Lih Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex I within Oxidatively Stressed Bovine Heart Mitochondria Is Glutathionylated on Cys-531 and Cys-704 of the 75-kDa Subunit

(2008) Thomas R. Hurd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ΔΨm-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

(2003) Tatyana V. Votyakova et al.   JOURNAL OF NEUROCHEMISTRY