Genetic and epigenetic characterization of posterior pituitary tumors

TTF-1 positive posterior pituitary tumor: Limitations of current treatment and potential new hope in BRAF V600E mutation variants

(2020) Fakhry M. Dawoud et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

The Gene Ontology resource: enriching a GOld mine

(2020) et al.   NUCLEIC ACIDS RESEARCH

Primary tumors of the posterior pituitary: A systematic review

(2019) Fernando Guerrero-Pérez et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA

(2019) Yanghao Hou et al.   ACTA NEUROPATHOLOGICA

Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas

(2019) Angela N. Viaene et al.   Acta Neuropathologica Communications

Panniculitis Under Successful Targeted Inhibition of the MAPK/ERK Signaling Pathway in a Patient With BRAF V600E-mutated Spindle Cell Oncocytoma of the Pituitary Gland

(2019) LUKAS SOLLFRANK et al.   ANTICANCER RESEARCH

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course

(2019) Annika K. Wefers et al.   ACTA NEUROPATHOLOGICA

RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression

(2019) Pascal David Johann et al.   BMC BIOINFORMATICS

The reactome pathway knowledgebase

(2019) Bijay Jassal et al.   NUCLEIC ACIDS RESEARCH

Diffuse glioneuronal tumour with oligodendroglioma‐like features and nuclear clusters (DGONC) – a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14

(2019) M. Y. Deng et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience

(2018) David Capper et al.   ACTA NEUROPATHOLOGICA

DNA methylation-based classification of central nervous system tumours

(2018) David Capper et al.   NATURE

A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle

(2018) Benjamin Goode et al.   Nature Communications

Hypothalamic Vasopressin-producing Tumors

(2018) Sylvia L. Asa et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

methylGSA: a Bioconductor package and Shiny app for DNA methylation data length bias adjustment in gene set testing

(2018) Xu Ren et al.   BIOINFORMATICS

The origins of the circumventricular organs

(2017) Clemens Kiecker   JOURNAL OF ANATOMY

Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent TSC1/TSC2 biallelic inactivation, and no BRAF mutations

(2017) Anika Bongaarts et al.   Oncotarget

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

(2016) Dominik Sturm et al.   CELL

Thyroid transcription factor-1 distinguishes subependymal giant cell astrocytoma from its mimics and supports its cell origin from the progenitor cells in the medial ganglionic eminence

(2016) Jen-Fan Hang et al.   MODERN PATHOLOGY

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy

(2016) Cassie N. Kline et al.   NEURO-ONCOLOGY

MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

(2016) Michael B. Miller et al.   Oncotarget

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

(2015) Kristian W. Pajtler et al.   CANCER CELL

Consistent nuclear expression of thyroid transcription factor 1 in subependymal giant cell astrocytomas suggests lineage-restricted histogenesis

(2015) Ekkehard Hewer et al.   CLINICAL NEUROPATHOLOGY

Suprasellar chordoid neoplasm with expression of thyroid transcription factor 1: evidence that chordoid glioma of the third ventricle and pituicytoma may form part of a spectrum of lineage-related tumors of the basal forebrain

(2015) Ekkehard Hewer et al.   HUMAN PATHOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

NbClust: AnRPackage for Determining the Relevant Number of Clusters in a Data Set

(2015) Malika Charrad et al.   Journal of Statistical Software

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Expression of thyroid transcription factor 1 in a chordoid glioma

(2014) A. Michotte et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Spindle Cell Oncocytomas and Granular Cell Tumors of the Pituitary Are Variants of Pituicytoma

(2013) Ozgur Mete et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Identification of a Novel, Recurrent SLC44A1-PRKCA Fusion in Papillary Glioneuronal Tumor

(2012) Julia A. Bridge et al.   BRAIN PATHOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

A tridimensional view of pituitary development and function

(2012) Patrice Mollard et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

(2011) Genevieve Schindler et al.   ACTA NEUROPATHOLOGICA

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

(2011) Sergey I Nikolaev et al.   NATURE GENETICS

Thyroid Transcription Factor 1 Expression in Sellar Tumors: A Histogenetic Marker?

(2009) Edward B. Lee et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Tandem Duplication Producing a Novel OncogenicBRAFFusion Gene Defines the Majority of Pilocytic Astrocytomas

(2008) David T.W. Jones et al.   CANCER RESEARCH

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

(2008) Stefan Pfister et al.   JOURNAL OF CLINICAL INVESTIGATION