Journal
BRITISH JOURNAL OF PSYCHIATRY
Volume 206, Issue 6, Pages 492-500Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.bp.114.150144
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Funding
- Commissioned Research on Mental Health Policy and Services of the Food and Health Bureau, Government of Hong Kong Special Administrative Region [SMH-29]
- Janssen-Cilag
- Eli Lilly
- Sanofi-Aventis
- Otsuka
- AstraZeneca
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Background Numerous early intervention services targeting young people with psychosis have been established, based on the premise that reducing treatment delay and providing intensive treatment in the initial phase of psychosis can improve long-term outcome. Aims To establish the effect of extending a specialised early intervention treatment for first-episode psychosis by 1 year. Method A randomised, single-blind controlled trial (NCT01202357) compared a 1-year extension of specialised early intervention with step-down care in patients who had all received a 2-year intensive early intervention programme for first-episode Results Patients receiving an additional year of specialised intervention had better outcomes in functioning, negative and depressive symptoms and treatment default rate than those managed by step-down psychiatric care. Conclusions Extending the period of specialised early intervention is clinically desirable but may not be feasible in lower-income countries. Copyright and usage (C) The Royal College of Psychiatrists 2015.
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