MESP1 Mutations in Patients with Congenital Heart Defects

The Transcription Factor Mesp1 Interacts with cAMP-responsive Element Binding Protein 1 (Creb1) and Coactivates Ets Variant 2 (Etv2) Gene Expression

(2015) Xiaozhong Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic basis of congenital cardiovascular malformations

(2014) Seema R. Lalani et al.   European Journal of Medical Genetics

Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development

(2014) Fabienne Lescroart et al.   NATURE CELL BIOLOGY

Complex Genetics and the Etiology of Human Congenital Heart Disease

(2014) B. D. Gelb et al.   Cold Spring Harbor Perspectives in Medicine

Mesp1 Patterns Mesoderm into Cardiac, Hematopoietic, or Skeletal Myogenic Progenitors in a Context-Dependent Manner

(2013) Sunny Sun-Kin Chan et al.   Cell Stem Cell

Of mice and men: molecular genetics of congenital heart disease

(2013) Troels Askhøj Andersen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mutational analysis of the human MESP1 gene in patients with congenital heart disease reveals a highly variable sequence in exon 1

(2013) Harald Lahm et al.   European Journal of Medical Genetics

De novo mutations in histone-modifying genes in congenital heart disease

(2013) Samir Zaidi et al.   NATURE

22q11.2 Deletions in Patients with Conotruncal Defects: Data from 1,610 Consecutive Cases

(2013) Shabnam Peyvandi et al.   PEDIATRIC CARDIOLOGY

Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest

(2013) Joshua W. Vincentz et al.   PLoS Genetics

Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects

(2011) Joshua W. Vincentz et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Defining the earliest step of cardiovascular progenitor specification during embryonic stem cell differentiation

(2011) Antoine Bondue et al.   JOURNAL OF CELL BIOLOGY

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

(2011) A. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined Mutation Screening of NKX2-5, GATA4, and TBX5 in Congenital Heart Disease: Multiple Heterozygosity and Novel Mutations

(2011) Javier T. Granados-Riveron et al.   Congenital Heart Disease

Microdeletions and Microduplications in Patients with Congenital Heart Disease and Multiple Congenital Anomalies

(2011) Elizabeth Goldmuntz et al.   Congenital Heart Disease

Mesp1

(2010) Antoine Bondue et al.   CIRCULATION RESEARCH

Mutational spectrum in the cardiac transcription factor gene NKX2.5 (CSX) associated with congenital heart disease

(2010) B Stallmeyer et al.   CLINICAL GENETICS

NKX2-5: an update on this hypermutable homeodomain protein and its role in human congenital heart disease (CHD)

(2010) Stella Marie Reamon-Buettner et al.   HUMAN MUTATION

A gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects

(2009) M. G. Posch et al.   JOURNAL OF MEDICAL GENETICS

A bHLH Code for Cardiac Morphogenesis

(2009) Simon J. Conway et al.   PEDIATRIC CARDIOLOGY

Mesp1 at the Heart of Mesoderm Lineage Specification

(2008) Sean M. Wu   Cell Stem Cell

Mesp1 Acts as a Master Regulator of Multipotent Cardiovascular Progenitor Specification

(2008) Antoine Bondue et al.   Cell Stem Cell

Mesp1 Coordinately Regulates Cardiovascular Fate Restriction and Epithelial-Mesenchymal Transition in Differentiating ESCs

(2008) R. Coleman Lindsley et al.   Cell Stem Cell

An absence of Twist1 results in aberrant cardiac neural crest morphogenesis

(2008) Joshua W. Vincentz et al.   DEVELOPMENTAL BIOLOGY

MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling

(2008) R. David et al.   NATURE CELL BIOLOGY