Variation at 2q35 (PNKDandTMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Implications of polygenic risk for personalised colorectal cancer screening

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Inflammatory and redox reactions in colorectal carcinogenesis

(2015) Tina Guina et al.   Annals of the New York Academy of Sciences

LENS: web-based lens for enrichment and network studies of human proteins

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Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer

(2015) Hamed Khalili et al.   CARCINOGENESIS

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

(2015) Jimmy Z Liu et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci

(2015) Roland Jäger et al.   Nature Communications

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

(2015) Nada A. Al-Tassan et al.   Scientific Reports

Interactions Between the Dietary Polyunsaturated Fatty Acid Ratio and Genetic Factors Determine Susceptibility to Pediatric Crohn's Disease

(2014) Irina Costea et al.   GASTROENTEROLOGY

Estimating the heritability of colorectal cancer

(2014) Shuo Jiao et al.   HUMAN MOLECULAR GENETICS

TMBIM protein family: ancestral regulators of cell death

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visPIG - A Web Tool for Producing Multi-Region, Multi-Track, Multi-Scale Plots of Genetic Data

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Architecture of Inherited Susceptibility to Colorectal Cancer: A Voyage of Discovery

(2014) Nicola Whiffin et al.   Genes

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements

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Transcription Factor Binding in Human Cells Occurs in Dense Clusters Formed around Cohesin Anchor Sites

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Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy   Cetuximab

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Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

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The Reactome pathway knowledgebase

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Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution But No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

(2012) Kati Kristiansson et al.   Circulation-Cardiovascular Genetics

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

(2012) Ulrike Peters et al.   GASTROENTEROLOGY

Annotation of functional variation in personal genomes using RegulomeDB

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Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

(2012) Malcolm G Dunlop et al.   NATURE GENETICS

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

(2012) Johannes Kettunen et al.   NATURE GENETICS

ChromHMM: automating chromatin-state discovery and characterization

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The BioGRID interaction database: 2013 update

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Early growth and coronary heart disease and type 2 diabetes: findings from the Helsinki Birth Cohort Study (HBCS)

(2011) Johan G Eriksson   AMERICAN JOURNAL OF CLINICAL NUTRITION

Cdc42 in oncogenic transformation, invasion, and tumorigenesis

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Intestinal Inflammation and Cancer

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Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

Mutations in PNKD causing paroxysmal dyskinesia alters protein cleavage and stability

(2011) Yiguo Shen et al.   HUMAN MOLECULAR GENETICS

Cohort Profile: The Corogene study

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Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial

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The MK5/PRAK Kinase and Myc Form a Negative Feedback Loop that Is Disrupted during Colorectal Tumorigenesis

(2011) Theresia R. Kress et al.   MOLECULAR CELL

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

(2011) Ian P. M. Tomlinson et al.   PLoS Genetics

A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface

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Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

(2010) Dermot P.B. McGovern et al.   HUMAN MOLECULAR GENETICS

Mechanisms by which inflammation may increase intestinal cancer risk in inflammatory bowel disease

(2010) Pamela M. OʼConnor et al.   INFLAMMATORY BOWEL DISEASES

Phase III Randomized Trial Assessing Rofecoxib in the Adjuvant Setting of Colorectal Cancer: Final Results of the VICTOR Trial

(2010) Rachel S. Midgley et al.   JOURNAL OF CLINICAL ONCOLOGY

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

(2010) Richard S Houlston et al.   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Biased Gene Conversion and the Evolution of Mammalian Genomic Landscapes

(2009) Laurent Duret et al.   Annual Review of Genomics and Human Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Wnt4 inhibits β-catenin/TCF signalling by redirecting β-catenin to the cell membrane

(2008) Pascal Bernard et al.   BIOLOGY OF THE CELL

Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS)

(2008) Tim Eisen et al.   BMC CANCER

Familial aggregation in Crohn's disease and ulcerative colitis in a Norwegian population-based cohort followed for ten years

(2008) May-Bente Bengtson et al.   Journal of Crohns & Colitis

Human Protein Reference Database--2009 update

(2008) T. S. Keshava Prasad et al.   NUCLEIC ACIDS RESEARCH

Cancer in inflammatory bowel disease

(2008) Jianlin Xie et al.   WORLD JOURNAL OF GASTROENTEROLOGY