Cystic fibrosis gene modifierSLC26A9modulates airway response to CFTR-directed therapeutics

A Joint Location-Scale Test Improves Power to Detect Associated SNPs, Gene Sets, and Pathways

(2015) David Soave et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Should diffuse bronchiectasis still be considered a CFTR-related disorder?

(2015) Anne Bergougnoux et al.   Journal of Cystic Fibrosis

Targeting ion channels in cystic fibrosis

(2015) Marcus A. Mall et al.   Journal of Cystic Fibrosis

Variants in Solute Carrier SLC26A9 Modify Prenatal Exocrine Pancreatic Damage in Cystic Fibrosis

(2015) Melissa R. Miller et al.   JOURNAL OF PEDIATRICS

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR

(2015) Claire E. Wainwright et al.   NEW ENGLAND JOURNAL OF MEDICINE

The UCSC Genome Browser database: 2016 update

(2015) Matthew L. Speir et al.   NUCLEIC ACIDS RESEARCH

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

(2015) Harriet Corvol et al.   Nature Communications

Testing gene therapy vectors in human primary nasal epithelial cultures

(2015) Huibi Cao et al.   Molecular Therapy-Methods & Clinical Development

VX-809 and Related Corrector Compounds Exhibit Secondary Activity Stabilizing Active F508del-CFTR after Its Partial Rescue to the Cell Surface

(2014) Paul D.W. Eckford et al.   CHEMISTRY & BIOLOGY

Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study

(2014) David Soave et al.   DIABETES

Functional interaction of the cystic fibrosis transmembrane conductance regulator with members of the SLC26 family of anion transporters (SLC26A8 and SLC26A9): Physiological and pathophysiological relevance

(2014) Elma El Khouri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cystic fibrosis genetics: from molecular understanding to clinical application

(2014) Garry R. Cutting   NATURE REVIEWS GENETICS

Integrative analysis of public ChIP-seq experiments reveals a complex multi-cell regulatory landscape

(2014) Aurélien Griffon et al.   NUCLEIC ACIDS RESEARCH

Loss of Slc26a9 anion transporter alters intestinal electrolyte and HCO3 - transport and reduces survival in CFTR-deficient mice

(2014) Xuemei Liu et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Change in Sweat Chloride as a Clinical End Point in Cystic Fibrosis Clinical Trials

(2013) Anthony G. Durmowicz et al.   CHEST

Genetic Modifiers of Cystic Fibrosis-Related Diabetes

(2013) S. M. Blackman et al.   DIABETES

Unraveling the complex genetic model for cystic fibrosis: pleiotropic effects of modifier genes on early cystic fibrosis-related morbidities

(2013) Weili Li et al.   HUMAN GENETICS

Characterization of SLC26A9 in Patients with CF-Like Lung Disease

(2013) Naziha Bakouh et al.   HUMAN MUTATION

Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene

(2013) Patrick R Sosnay et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Correction of Both NBD1 Energetics and Domain Interface Is Required to Restore ΔF508 CFTR Folding and Function

(2012) Wael M. Rabeh et al.   CELL

Deficiency of Sbds in the Mouse Pancreas Leads to Features of Shwachman–Diamond Syndrome, With Loss of Zymogen Granules

(2012) Marina E. Tourlakis et al.   GASTROENTEROLOGY

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation

(2012) Pinelopi Anagnostopoulou et al.   JOURNAL OF CLINICAL INVESTIGATION

Ivacaftor potentiation of multiple CFTR channels with gating mutations

(2012) Haihui Yu et al.   Journal of Cystic Fibrosis

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis

(2012) Lei Sun et al.   NATURE GENETICS

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2

(2011) Fred A Wright et al.   NATURE GENETICS

A CFTR Potentiator in Patients with Cystic Fibrosis and theG551DMutation

(2011) Bonnie W. Ramsey et al.   NEW ENGLAND JOURNAL OF MEDICINE

A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis Genetic modifier studies

(2011) Chelsea Taylor et al.   PEDIATRIC PULMONOLOGY

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

(2011)   PLOS BIOLOGY

Cystic Fibrosis Transmembrane Conductance Regulator Channel Dysfunction in Non–Cystic Fibrosis Bronchiectasis

(2010) Thierry Bienvenu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis

(2010) Patrick H. Thibodeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLC26A9 stimulates CFTR expression and function in human bronchial cell lines

(2010) Martine Avella et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Quantitative expression analyses of candidates for alternative anion conductance in cystic fibrosis mouse models

(2010) Josephine Braun et al.   Journal of Cystic Fibrosis

Detection of nonneutral substitution rates on mammalian phylogenies

(2009) K. S. Pollard et al.   GENOME RESEARCH

Slc26a9 Is Inhibited by the R-region of the Cystic Fibrosis Transmembrane Conductance Regulator via the STAS Domain

(2009) Min-Hwang Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia

(2009) Carol A. Bertrand et al.   JOURNAL OF GENERAL PHYSIOLOGY

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

(2009) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The intact CFTR protein mediates ATPase rather than adenylate kinase activity

(2008) Mohabir Ramjeesingh et al.   BIOCHEMICAL JOURNAL

Characterization of SLC26A9, Facilitation of Cl- Transport by Bicarbonate

(2008) Celine Loriol et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Interactions Between Secondhand Smoke and Genes That Affect Cystic Fibrosis Lung Disease

(2008) J. Michael Collaco et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Diverse transport modes by the solute carrier 26 family of anion transporters

(2008) Ehud Ohana et al.   JOURNAL OF PHYSIOLOGY-LONDON

Reference Ranges for Spirometry Across All Ages

(2007) Sanja Stanojevic et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE