Conserved pharmacological rescue of hereditary spastic paraplegia-related phenotypes across model organisms

Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders

(2015) Surya T. Madabattula et al.   Jove-Journal of Visualized Experiments

Heritable Transmission of Stress Resistance by High Dietary Glucose in Caenorhabditis elegans

(2014) Arnaud Tauffenberger et al.   PLoS Genetics

Low dose tubulin-binding drugs rescue peroxisome trafficking deficit in patient-derived stem cells in Hereditary Spastic Paraplegia

(2014) Y. Fan et al.   Biology Open

Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms

(2013) John K. Fink   ACTA NEUROPATHOLOGICA

An ESCRT–spastin interaction promotes fission of recycling tubules from the endosome

(2013) Rachel Allison et al.   JOURNAL OF CELL BIOLOGY

Evaluation of longevity enhancing compounds against transactive response DNA-binding protein-43 neuronal toxicity

(2013) Arnaud Tauffenberger et al.   NEUROBIOLOGY OF AGING

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo

(2013) Alexandra Vaccaro et al.   NEUROBIOLOGY OF DISEASE

Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C. elegans

(2013) Martine Therrien et al.   PLoS One

Role of spastin and protrudin in neurite outgrowth

(2012) Chuanling Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Methylene Blue Protects against TDP-43 and FUS Neuronal Toxicity in C. elegans and D. rerio

(2012) Alexandra Vaccaro et al.   PLoS One

Genetics of Hereditary Spastic Paraplegias

(2012) Rebecca Schüle et al.   SEMINARS IN NEUROLOGY

Normal Spastin Gene Dosage Is Specifically Required for Axon Regeneration

(2012) Michelle C. Stone et al.   Cell Reports

Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia

(2010) R. Butler et al.   Disease Models & Mechanisms

A Class of Dynamin-like GTPases Involved in the Generation of the Tubular ER Network

(2009) Junjie Hu et al.   CELL

Conserved aromatic and basic amino acid residues in the pore region ofCaenorhabditis elegansspastin play critical roles in microtubule severing

(2009) Yuka Matsushita-Ishiodori et al.   GENES TO CELLS

Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin

(2009) Genny Orso et al.   NATURE

Atlastin GTPases are required for Golgi apparatus and ER morphogenesis

(2008) Neggy Rismanchi et al.   HUMAN MOLECULAR GENETICS

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

(2008) Sara Salinas et al.   LANCET NEUROLOGY

The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches

(2008) Wenqian Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory

(2008) François V Bolduc et al.   NATURE NEUROSCIENCE