A variant in TMPRSS2 is associated with decreased disease severity in COVID-19

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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Could the D614 G substitution in the SARS-CoV-2 spike (S) protein be associated with higher COVID-19 mortality?

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ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy

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New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

(2020) Yuan Hou et al.   BMC Medicine

Assessment of risk conferred by coding and regulatory variations of TMPRSS2 and CD26 in susceptibility to SARS-CoV-2 infection in human

(2020) Sabyasachi Senapati et al.   JOURNAL OF GENETICS

Estimates of the severity of coronavirus disease 2019: a model-based analysis

(2020) Robert Verity et al.   LANCET INFECTIOUS DISEASES

Risk factors for death in 1859 subjects with COVID-19

(2020) Lei Chen et al.   LEUKEMIA

Factors associated with COVID-19-related death using OpenSAFELY

(2020) Elizabeth J. Williamson et al.   NATURE

Genomewide Association Study of Severe Covid-19 with Respiratory Failure

(2020) David Ellinghaus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19

(2020) Madalina Elena Carter-Timofte et al.   Frontiers in Immunology

Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters

(2020) John P.A. Ioannidis et al.   ENVIRONMENTAL RESEARCH

Racial/Ethnic Variation in Nasal Gene Expression of Transmembrane Serine Protease 2 (TMPRSS2)

(2020) Supinda Bunyavanich et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneity

(2020) M. Rafiul Islam et al.   Scientific Reports

PhyreRisk: A Dynamic Web Application to Bridge Genomics, Proteomics and 3D Structural Data to Guide Interpretation of Human Genetic Variants

(2019) Tochukwu C. Ofoegbu et al.   JOURNAL OF MOLECULAR BIOLOGY

ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK

(2018) Soma Behera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer

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