Article
Medicine, General & Internal
Grace O. Dibben, Melvyn Hillsdon, Hasnain M. Dalal, Lars H. Tang, Patrick Joseph Doherty, Rod Taylor
Summary: This study aimed to quantify the impact of a home-based cardiac rehabilitation intervention (REACH-HF) on objectively assessed physical activity (PA) of heart failure (HF) patients, and explore the associations between patient characteristics and changes in PA. The results showed that although there was no significant difference in overall PA levels between the REACH-HF intervention group and the control group, the REACH-HF group had increased weekday MVPA, light PA, and decreased inactivity compared to the control group. Baseline PA levels were found to be highly predictive of PA change.
Article
Psychology, Multidisciplinary
Akiyoshi Shimura, Katsunori Yokoi, Yoshiki Ishibashi, Yusaku Akatsuka, Takeshi Inoue
Summary: Remote work was found to reduce psychological and physical stress responses, but full-remote work of 5 days a week was associated with decreased work productivity. This suggests that changing work styles can have positive effects on mental health even after the end of the pandemic.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Medicine, General & Internal
Agnieszka Grochulska, Sebastian Glowinski, Aleksandra Bryndal
Summary: This study demonstrates that cardiac rehabilitation significantly improves physical performance in patients after myocardial infarction, as indicated by increased exercise stress test time, MET, VO2max, and 6MWT score.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Francesca Denton, Alexander Waddell, Chris Kite, Katie Hesketh, Lou Atkinson, Matthew Cocks, Helen Jones, Harpal Randeva, Nathan Davenport, Richard Powell, Cain Clark, Ioannis Kyrou, Amy E. Harwood, Gordon McGregor
Summary: The aim of this study is to assess the feasibility of a remotely prescribed, delivered and monitored cardiac rehabilitation intervention using a wearable device to support long-term adherence to exercise and physical activity during maintenance of cardiac rehabilitation. The study will randomize 30 participants with CHD to an intervention or a usual care group, and assess feasibility, exercise capacity, physical activity behaviors, cardiovascular disease risk, and quality of life as outcomes. Semi-structured interviews will be conducted to explore the acceptability of the study intervention and procedures.
Article
Medicine, General & Internal
Misato Chimura, Shinji Koba, Yasushi Sakata, Takayuki Ise, Hiroyuki Miura, Ryosuke Murai, Hiroshi Suzuki, Emi Maekawa, Keisuke Kida, Koki Matsuo, Hirokazu Kondo, Kensuke Takabayashi, Wataru Fujimoto, Yuichi Tamura, Shunsuke Imai, Shin-ichiro Miura, Hideki Origuchi, Akiko Goda, Ryotaro Saita, Atsushi Kikuchi, Tatsunori Taniguchi
Summary: This article introduces a home-based cardiac rehabilitation program using the integrated telerehabilitation platform RH-01, aiming to improve the prognosis and quality of life of patients with heart failure. The E-REHAB trial evaluates the efficacy and safety of RH-01 compared with traditional centre-based cardiac rehabilitation for heart failure patients, and also includes patients with other cardiovascular diseases. The trial will enroll 108 heart failure patients and 20 patients with other cardiovascular diseases, using a prospective, randomized, controlled and non-inferiority design.
Article
Medicine, General & Internal
Jing Jing Piao, Boya Wan, Haomei Zhao, Zhiyang Shang, Lingjun Yan, Zhina Hao, Yonghong Wang, Yanqing Zhang, Yanmei Gu
Summary: This study aims to test whether low-intensity or medium-intensity brisk walking is more helpful in improving early attendance, adherence, and physical results of cardiac rehabilitation patients. The study will compare the effects of low-intensity and medium-intensity brisk walking and collect primary and secondary outcome data.
Article
Cardiac & Cardiovascular Systems
Sisi Zhang, Rongjing Ding, Sikun Chen, Xiaoping Meng, Li Jianchao, Daowen Wang, Dayi Hu
Summary: The study aimed to assess the status of cardiac rehabilitation programs in China by analyzing data from a national registry. Data from nearly 20,000 cardiovascular disease patients in 159 hospitals across 34 provinces were extracted. The study found regional variations in participation, with the majority of patients located in eastern China. Male patients under 60 years old with low risk for coronary heart disease were more likely to undergo hospital-based cardiac rehabilitation. The findings highlight the need for improving participation and uptake of cardiac rehabilitation in China.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Derek L. Tran, David S. Celermajer, Julian Ayer, Leeanne Grigg, Carley Clendenning, Tim Hornung, Robert Justo, Glen M. Davis, Yves d'Udekem, Rachael Cordina
Summary: The study indicates that the Super-Fontan phenotype is associated with a healthy weight, lower age at Fontan completion, better exercise self-efficacy, and higher overall levels of sport and physical activity participation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Rehabilitation
Yuta Nakaya, Masanori Akamatsu, Akiyoshi Ogimoto, Hiroaki Kitaoka
Summary: This study aimed to evaluate whether the addition of multidisciplinary physical interventions to the standard cardiac rehabilitation program could effectively improve Short Physical Performance Battery (SPPB) among elderly patients with acute decompensated heart failure (ADHF), regardless of the type of heart failure. The results showed that this intervention significantly improved the SPPB scores of elderly ADHF patients, particularly those with preserved ejection fraction heart failure.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Review
Nursing
Yan Gao, Nan Wang, Lixin Zhang, Naiquan Liu
Summary: This systematic review and meta-analysis evaluated the effectiveness of home-based cardiac telerehabilitation in heart failure patients. The results from 16 studies with 4557 participants showed that home-based cardiac telerehabilitation can improve heart rate, VO2 peak, 6-minute walk distance, quality of life, and reduce readmission rates. It may be used as an adjunct or substitute for centre-based cardiac rehabilitation.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Nursing
Jing Jing Su, Doris Sau-Fung Yu
Summary: The nurse-led eHealth cardiac rehabilitation (NeCR) system showed significant improvements in health behaviors, self-efficacy, health-related quality of life, and other outcomes for patients with coronary heart disease, highlighting the effectiveness of the intervention.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2021)
Article
Cardiac & Cardiovascular Systems
Kirstine L. Sibilitz, Lars Hermann Tang, Selina Kikkenborg Berg, Lau Caspar Thygesen, Signe Stelling Risom, Trine Bernholdt Rasmussen, Jean-Paul Schmid, Britt Borregaard, Christian Hassager, Lars Kober, Rod S. Taylor, Ann-Dorthe Zwisler
Summary: Cardiac rehabilitation after heart valve surgery can reduce readmissions and mortality within 12 months, but its long-term effects on exercise capacity, physical, and mental health are unclear.
SCANDINAVIAN CARDIOVASCULAR JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Ernesto Dalli-Peydro, Rafael Gisbert-Criado, Nuria Amigo, Nuria Sanz-Sevilla, Juan Cosin-Sales
Summary: The study compared cardiac telerehabilitation (CTR) with centre-based cardiac rehabilitation (CBCR) and found that CTR can reduce GlycA levels, TG/HDL ratio, and prevent unfavorable long-term changes in lipoprotein particle composition.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Chemistry, Analytical
Boldizsar Kovacs, Flavia Muller, David Niederseer, Nazmi Krasniqi, Ardan M. Saguner, Firat Duru, Matthias Hermann
Summary: The study found a positive correlation between the median daily step count measured by the WCD's accelerometer and the 6MWT, suggesting it could be used as a surrogate for assessing cardiopulmonary exercise capacity. Remote monitoring of daily step count and activity level via the WCD may aid in providing tailored exercise instructions for patients not participating in cardiac rehabilitation.
Article
Cardiac & Cardiovascular Systems
Sean Coffey, Parul Dixit, Eng Leng Saw, Aram A. Babakr, Isabelle van Hout, Ivor F. Galvin, Pankaj Saxena, Richard W. Bunton, Philip J. Davis, Regis R. Lamberts, Rajesh Katare, Michael J. A. Williams
Summary: The study examined whether thiamine would improve Cardiac Progenitor Cell (CPC) function in humans, but found that it did not improve CPC proliferation ability in patients undergoing coronary artery bypass surgery (CABG). However, thiamine did increase the proportion of CD34(-)/CD105(+) cells in isolated CPCs.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Anne-Sophie Juul, Kasper Kyhl, Kathrine Ekstr, Jasmine Melissa Madsen, Muhammad Sabbah, Kiril Aleksov Ahtarovski, Lars Nepper-Christensen, Niels Vejlstrup, Dan Hofsten, Henning Kelbaek, Lars Kober, Jacob Lonborg, Thomas Engstrom
Summary: Mounting evidence shows that right ventricle (RV) function carries independent prognostic influence in various disease states. This study investigated the incidence and impact of permanent RV infarction in patients with inferior ST-segment elevation myocardial infarction (STEMI) and culprit lesion in the right coronary artery (RCA). The results revealed that permanent RV infarction occurred in 20% of these patients and independently predicted the size of the final left ventricular infarct.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jonas Bruhn, Morten Malmborg, Caroline H. Garred, Pauline Ravn, Deewa Zahir, Charlotte Andersson, Gunnar Gislason, Christian Torp-Pedersen, Kristian Kragholm, Emil Fosbol, Jawad H. Butt, Ninian N. Lang, Mark C. Petrie, John McMurray, Lars Kober, Morten Schou
Summary: This study investigated the temporal trends of new onset cancer in patients with HF between 1997 and 2016. It found that the incidence of cancer did not increase over time in HF patients, but long-term survival following an HF diagnosis significantly increased.
EUROPEAN HEART JOURNAL
(2023)
Article
Medicine, General & Internal
Nils Skajaa, Kasper Adelborg, Erzsebet Horvath-Puho, Kenneth J. Rothman, Victor W. Henderson, Lau Caspar Thygesen, Henrik Toft Sorensen
Summary: This study examined labor market participation and retirement among stroke patients and the general population, focusing on different subtypes of stroke. The results showed that most patients took sick leave within three weeks of diagnosis and were less likely to return to the labor market, especially those with intracerebral hemorrhage. The main reasons for non-participation in the labor market were sick leave and receipt of a disability pension.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Anika Klein, Johannes Grand, Martin Abild Stengaard Meyer, Sebastian Wiberg, Rasmus Mogelvang, Niels Vejlstrup, Birgitte Schousboe, Jakob Gjedsted, Morten Oestergaard, Michael Wanscher, Jesper Kjaergaard, Christian Hassager
Summary: This study used cardiac magnetic resonance (CMR) to assess the presence of early myocardial edema in patients successfully resuscitated from out-of-hospital cardiac arrest (OHCA). The study found that myocardial edema is commonly present in such patients. This study is important for understanding the underlying mechanisms of myocardial dysfunction after OHCA.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2023)
Article
Cardiac & Cardiovascular Systems
Elke Platz, Brian Claggett, Karola S. Jering, Attila Kovacs, Maja Cikes, Ephraim B. Winzer, Aria Rad, Martin P. Lefkowitz, Jianjian Gong, Lars Kober, John J. McMurray, Scott D. Solomon, Marc A. Pfeffer, Amil Shah
Summary: This study examined the efficacy of sacubitril/valsartan in patients with acute myocardial infarction (AMI) and reduced left ventricular ejection fraction (LVEF), pulmonary congestion, or both. The study used lung ultrasound (LUS) to assess the trajectory of pulmonary congestion and its association with cardiac structure and function.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2023)
Article
Health Care Sciences & Services
Anne Katrine Graudal Levinsen, Trille Kristina Kjaer, Thomas Maltesen, Erik Jakobsen, Ismail Gogenur, Michael Borre, Peer Christiansen, Robert Zachariae, Soren Laurberg, Peter Christensen, Niels Kroman, Signe Benzon Larsen, Thea Helene Degett, Lisbet Rosenkrantz Holmich, Peter de Nully Brown, Christoffer Johansen, Susanne K. Kjaer, Lau Caspar Thygesen, Susanne Oksbjerg Dalton
Summary: Cancer survivors use more healthcare services compared to cancer-free individuals. There is a correlation between educational level and healthcare use, with survivors with lower education being more likely to use general practitioner and acute healthcare services.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Critical Care Medicine
Mik Wetterslev, Morten Hylander Moller, Anders Granholm, Christian Hassager, Nicolai Haase, Theis N. Lange, Sheila Myatra, Johanna M. Hastbacka, Yaseen Arabi, Jiawei Shen, Maria Cronhjort, Elin Lindqvist, Anders J. Aneman, Paul Young, Wojciech Szczeklik, Martin Siegemund, Thijs Koster, Tayyba Naz H. Aslam, Morten S. Bestle, Mia Girkov, Kushal Kalvit, Rakesh Mohanty, Joanne Mascarenhas, Manoranjan Pattnaik, Sara Vergis, Sai Praveen Haranath, Mehul Shah, Ziyokov Joshi, Erika Wilkman, Matti Reinikainen, Pasi Lehto, Ville Jalkanen, Anni Pulkkinen, Youzhong An, Guoxing Wang, Lei Huang, Bin Huang, Wei Liu, Hengbo Gao, Lin Dou, Shuangling Li, Wanchun Yang, Emily Tegnell, Agnes Knight, Miroslaw Czuczwar, Tomasz Czarnik, Anders Perner
Summary: This study aimed to assess the incidence, risk factors, and outcomes of atrial fibrillation (AF) in ICU and described the current practice in the management of AF. The results showed that the incidence of AF was 15.6%, with newly developed AF accounting for 13.3%. Factors associated with AF included arterial hypertension, paroxysmal AF, sepsis, or high disease severity at ICU admission. There were variations in the diagnostic and management strategies for AF, and AF was associated with worse outcomes.
CRITICAL CARE MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jawad H. Butt, Brian L. Claggett, Zi M. Miao, Karola S. Jering, David Sim, Peter van der Meer, Mpiko Ntsekhe, Offer Amir, Myeong-Chan Cho, Jorge Carrillo-Calvillo, Julio E. Nunez, Alberto Cadena, Prafulla Kerkar, Aldo P. Maggioni, Philippe G. Steg, Christopher B. Granger, Douglas L. Mann, Bela Merkely, Eldrin F. Lewis, Scott D. Solomon, Yinong Zhou, Lars Kober, Eugene Braunwald, John J. V. McMurray, Marc A. Pfeffer
Summary: This study investigated the geographic differences in patient characteristics, treatments, and outcomes in global clinical trials. Patients from Asia, especially South Asia, differed from patients in other regions in terms of age, weight, comorbidities, type of myocardial infarction, and treatment. On the other hand, patients from Latin America did not differ significantly from European or North American patients. These findings highlight the importance of considering regional differences when designing global clinical trials.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Antonio Molinaro, Ina Nemet, Pierre Bel Lassen, Rima Chakaroun, Trine Nielsen, Judith Aron-Wisnewsky, Per-Olof Bergh, Lin Li, Marcus Henricsson, Lars Kober, Richard Isnard, Gerard Helft, Michael Stumvoll, Oluf Pedersen, J. Gustav Smith, W. H. Wilson Tang, Karine Clement, Stanley L. Hazen, Fredrik Backhed
Summary: The gut microbial metabolite ImP is associated with heart failure and predicts overall survival. This study sheds light on the relationship between ImP and heart failure.
JACC-HEART FAILURE
(2023)
Letter
Cardiac & Cardiovascular Systems
Jawad H. Butt, Adelina Yafasova, Seiko N. Doi, Jens C. Nielsen, Jens Haarbo, Hans Eiskjaer, Axel Brandes, Anna M. Thogersen, Finn Gustafsson, Christian Hassager, Jesper H. Svendsen, Dan E. Hofsten, Lars Videbaek, Christian Torp-Pedersen, Steen Pehrson, Jens Jakob Thune, Lars Kober
Article
Cardiac & Cardiovascular Systems
Naja Emborg Vinding, Jawad H. Butt, Marie Dam Lauridsen, Soren Lund Kristensen, Soren Paaske Johnsen, Johanna Kroll, Peter L. Graversen, Christina Kruuse, Christian Torp-Pedersen, Lars Kober, Emil L. Fosbol
Summary: The incidence of ischemic stroke after a first-time transient ischemic attack (TIA) is 6.1% during a 5-year follow-up period, which is higher than the background population but lower than patients with recurrent ischemic stroke. TIA patients also have a higher mortality rate.
Article
Cardiac & Cardiovascular Systems
Mingming Yang, Toru Kondo, Carly Adamson, Jawad H. Butt, William T. Abraham, Akshay S. Desai, Karola S. Jering, Lars Kober, Mikhail N. Kosiborod, Milton Packer, Jean L. Rouleau, Scott D. Solomon, Muthiah Vaduganathan, Michael R. Zile, Pardeep S. Jhund, John J. V. McMurray
Summary: This study aimed to assess the relationship between patient-reported knowledge of self-management and clinical outcomes in patients with heart failure and reduced ejection fraction (HFrEF). It was found that poor self-rated knowledge may be associated with higher rates of mortality. Evaluation of knowledge of 'self-efficacy' may provide prognostic information and a guide to which patients may benefit from further education about self-management.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Mingming Yang, Toru Kondo, Carly Adamson, Jawad H. Butt, William T. Abraham, Akshay S. Desai, Karola S. Jering, Lars Kober, Mikhail N. Kosiborod, Milton Packer, Jean L. Rouleau, Scott D. Solomon, Muthiah Vaduganathan, Michael R. Zile, Pardeep S. Jhund, John J. V. McMurray
Summary: This study aimed to assess the impact of different comorbidities on health status in patients with HFpEF and HFrEF. The results showed that chronic obstructive pulmonary disease, angina, anaemia, and obesity were associated with reduced health status. Patients with multiple comorbidities had worse health status.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Correction
Cardiac & Cardiovascular Systems
James P. Curtain, Carly Adamson, Toru Kondo, Jawad Haider Butt, Akshay S. Desai, Faiez Zannad, Jean L. Rouleau, Luis E. Rohde, Lars Kober, Inder S. Anand, Dirk J. van Veldhuisen, Michael R. Zile, Martin P. Lefkowitz, Scott D. Solomon, Milton Packer, Mark C. Petrie, Pardeep S. Jhund, John J. V. McMurray
EUROPEAN HEART JOURNAL
(2023)
Article
Urology & Nephrology
Katja Vu Bartholdy, Niklas Dyrby Johansen, Nino Landler, Kristoffer Grundtvig Skaarup, Jesper Jensen, Iain Bressendorff, Morten Schou, Jacob Christensen, Bo Feldt-Rasmussen, Muthiah Vaduganathan, Scott Solomon, Richard Haynes, Frederik Persson, Peter Rossing, Lars Kober, Faiez Zannad, Ditte Hansen, Tor Biering-Sorensen
Summary: This study aims to evaluate the effects of SGLT2 inhibitors on cardiac structure and function in patients with CKD. The results will provide insights into the cardioprotective mechanisms of SGLT2 inhibitors in patients with CKD.