Hepatic-specific PPARα-FGF21 action in NAFLD

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

(2016) Alexandra Montagner et al.   GUT

FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss

(2014) Bryn M. Owen et al.   Cell Metabolism

FGF21 Maintains Glucose Homeostasis by Mediating the Cross Talk Between Liver and Brain During Prolonged Fasting

(2014) Q. Liang et al.   DIABETES

Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

(2014) K. R. Markan et al.   DIABETES

FGF21 contributes to neuroendocrine control of female reproduction

(2013) Bryn M Owen et al.   NATURE MEDICINE

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

(2013) Angie L Bookout et al.   NATURE MEDICINE

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

(2012) Xunshan Ding et al.   Cell Metabolism

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT