Article
Chemistry, Organic
Huicong Xing, Meijuan Chen, Dong Zhang, Zhishuai Geng, Peizhong Xie, Teck-Peng Loh
Summary: A transition-metal-free catalytic system was developed for the dehydrative cross-coupling of unactivated primary/secondary alcohols with amines/amides, achieving the cleavage of C-OH bond and formation of C-N bond under environmentally benign conditions.
Article
Nanoscience & Nanotechnology
Sobin Mathew, Ki-Hyun Park, Youri Han, Kwun Nam Hui, Oi Lun Li, Young-Rae Cho
Summary: A novel metal-free catalyst with remarkable activity in the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) was synthesized. The catalyst exhibited low overpotential when deposited on a conductive nickel foam substrate. Additionally, it displayed lower operating potentials and good stability in an alkaline anion-exchange membrane electrolyzer.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Lanfeng Wei, Wenbo Bai, Zhiyan Hu, Zhiyong Yang, Liang Xu
Summary: The study developed a unified metal-free photooxidative platform for the cleavage of C-heteroatom bonds, using AQDAB complex as the photocatalyst to induce the oxidation process. This method allows for chemoselective cleavage of C-N, C-S, and C-Se bonds, broadening the potential applications of oxidation in synthetic chemistry. It established a photooxidation system for formal carbonylation of C-heteroatom (N, S, Se) bonds.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Zhao-Nan Cai, Xiang-Xuan Feng, Yuecheng Zhang, Cong-Cong Lu, Ya-Ping Han, Jiquan Zhao
Summary: A novel, green, and transition-metal-free protocol for modifying quinoline and isoquinoline derivatives was introduced, which provides efficient and atom-economical access to fascinating products. The method features good functional group compatibility, operational simplicity, and produces water as the only byproduct. It is also effective on the gram scale, highlighting its practicality.
CHINESE JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Organic
Jake J. Blackner, Deirdre M. Rooney, Joshua W. Hollett, J. Adam McCubbin
Summary: A boronic acid catalyzed carbon-carbon and carbon-nitrogen bond-forming reaction using ferrocenium boronic acid hexafluoroantimonate salt as catalyst has been developed for the functionalization of various pi-activated alcohols. The reaction proceeds under mild conditions and yields up to 98%, with higher yields and selectivity observed when using organosilane nucleophiles. Computational studies provide a mechanistic pathway for the retention of E/Z stereochemistry when using alkenyl silanes as nucleophiles. This methodology is effective with a variety of organosilane nucleophile sub-types, including allylic, vinylic, and propargylic trimethylsilanes.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Farzaneh Soleymani Movahed, Siong Wan Foo, Shogo Mori, Saeko Ogawa, Susumu Saito
Summary: A metal-free, biomimetic catalytic protocol has been developed for the cyclization of N-(2-hydroxyethyl)amides to 2-oxazolines, achieving high substrate scope and functional-group tolerance with high product yields.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Ajay Sharma, Satyendra Kumar Pandey
Summary: An efficient and concise organocatalyzed protecting-group free synthetic approach is described for synthesizing the stereoisomers of the antidepressant drug reboxetine. The synthesis involves organocatalytic Jorgensen asymmetric epoxidation, epoxide migration, and Mitsunobu inversion as key steps.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Lei Xie, Xuyang Zang, Wanxing Liu, Ping Wu, Zhaoxue Wang, Chenyi Zhao, Zhenzhen Gao, Xiaojing Li, Shaozhen Nie, Lingang Wu
Summary: An efficient method for the synthesis of a variety of large diarylmethane thioether derivatives is developed through catalyst-free 1,6-conjugate addition. The reaction yields high to excellent results, and the system is also suitable for other sulfur-based nucleophiles. The resulting products can be readily converted into other valuable diarylmethane derivatives.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Jennifer Solarczek, Felix Kaspar, Pia Bauer, Anett Schallmey
Summary: This study explores the substrate scope of G-type halohydrin dehalogenases with sterically demanding cyclic epoxides and anionic nucleophiles, demonstrating their ability to facilitate a variety of ring-opening reactions and significantly expand the repertoire of accessible transformations.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Shinji Tanaka, Masato Kitamura
Summary: The modification of allyl alcohol to allyl ester or halide in dehydrative allylation reaction is achieved using two redox-mediated donor acceptor bifunctional catalyst systems, expanding the application scope and facilitating the utilization of various nucleophiles with aliphatic and aromatic allylic alcohols.
Article
Chemistry, Multidisciplinary
Xiangli Yi, Runze Mao, Lara Lavrencic, Xile Hu
Summary: The study presents a decarboxylative coupling reaction using photoredox and copper catalysis to convert alkyl carboxylic acids into polyfluoroaryl compounds. The method demonstrates broad scope and good functional group compatibility, with the potential to achieve a wide range of F-substitution patterns on the aryl groups. Mechanistic study suggests a [Cu-(Ar-F)(2)] species may be responsible for the transfer of polyfluoroaryl groups to alkyl radicals.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Nitin Tandon, Shripad M. Patil, Runjhun Tandon, Pushpendra Kumar
Summary: Novel silica-coated ferrite nanoparticles supported with montmorillonite (K-10) were successfully prepared via a simple impregnation method and characterized using various analytical techniques. These nanoparticles exhibited good catalytic activity in acylation reactions and could be easily separated and reused through an external magnetic field.
Article
Chemistry, Organic
Chun-Tai Hung, Chun-Wei Lu, Shi-Han Huang, Yin-Feng Lu, Hsiang-Chi Chou, Cheng-Che Tsai
Summary: This research utilizes chiral sulfinamides as nucleophiles in intramolecular allylic substitution and sequential aerobic oxidation with aza-Michael addition reactions, achieving good yields of chiral isoindolines and high diastereoselectivities.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Debabrat Pathak, Bikash Kumar Kalita, Ashish Sarmah, Himanshu Sharma, Bidisha Bora, Tridib K. Goswami, Bipul Sarma
Summary: We present a greener synthetic route for the synthesis of medicinally and industrially valuable quinoline scaffolds, eliminating harsh reaction conditions, low productivity, and unstable substrates associated with classical methods. This route involves the acceptorless dehydrogenative annulation of readily available alcohols in basic media using an engineered nitrogen-rich hollow-spherical microporous polymer (MOP-TA) without any metal support. The scalability and green matrices of this affordable and sustainable route are supported by various spectroscopic and microscopic techniques.
Article
Chemistry, Multidisciplinary
Hai-Lang Jia, Hong-Cheng Li, Jiao Zhao, Ming-Yun Guan
Summary: In this study, an excellent HER catalyst was prepared by utilizing a doping strategy and embedding ruthenium nanoparticles on carbon nanotubes. The catalytic performance of this catalyst surpassed that of commercial platinum catalysts. The catalyst exhibited outstanding performance under both acidic and alkaline conditions, and it was found that the dispersed ruthenium nanoparticles played a crucial role in HER catalysis.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Shuai Zhu, Chunqi Chen, Mingyan Xiao, Liping Yu, Liang Wang, Jian Xiao
Article
Chemistry, Organic
Shuai-Shuai Li, Shiheng Fu, Liang Wang, Lubin Xu, Jian Xiao
JOURNAL OF ORGANIC CHEMISTRY
(2017)
Article
Chemistry, Organic
Shuai-Shuai Li, Lan Zhou, Liang Wang, Huaili Zhao, Liping Yu, Jian Xiao
Review
Chemistry, Organic
Mingyan Xiao, Shuai Zhu, Yaobin Shen, Liang Wang, Jian Xiao
CHINESE JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Polymer Science
Xi Yu, Pengfei Yang, Zhiliang Zhang, Liang Wang, Lian Liu, Yongqing Wang
JOURNAL OF APPLIED POLYMER SCIENCE
(2018)
Article
Biochemistry & Molecular Biology
Xi Yu, Liang Wang, Pengfei Yang, Jinku Xu, Mark G. Moloney, Lian Liu, Yunlin Pan, Yongqing Wang
MACROMOLECULAR BIOSCIENCE
(2018)
Article
Chemistry, Organic
Wei Cao, Ping Chen, Liang Wang, Hao Wen, Yu Liu, Wanshu Wang, Yu Tang
Article
Chemistry, Physical
Yujian Mao, Ye Liu, Yanwei Hu, Liang Wang, Shilei Zhang, Wei Wang
Editorial Material
Chemistry, Organic
Lubin Xu, Pengfei Yang, Liang Wang
ORGANIC CHEMISTRY FRONTIERS
(2018)
Article
Chemistry, Organic
Chunqi Chen, Lubin Xu, Liang Wang, Shuai-Shuai Li
ORGANIC & BIOMOLECULAR CHEMISTRY
(2018)
Article
Chemistry, Organic
Yao-Bin Shen, Shuai-Shuai Li, Liang Wang, Xiao-De An, Qing Liu, Xicheng Liu, Jian Xiao
Article
Chemistry, Organic
Hao Wen, Wei Cao, Yu Liu, Liang Wang, Ping Chen, Yu Tang
JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Chemistry, Organic
Didi Ren, Lubin Xu, Liang Wang, Shuai-Shuai Li
Article
Biochemistry & Molecular Biology
Manli Yang, Liang Wang, Yanzhi Xia
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Chemistry, Multidisciplinary
Xi Yu, Pengfei Yang, Mark G. Moloney, Liang Wang, Jinku Xu, Yongqing Wang, Lian Liu, Yunlin Pan
Article
Chemistry, Multidisciplinary
Xuemei Liu, Chaonan Cui, Shuoshuo Wei, Jinyu Han, Xinli Zhu, Qingfeng Ge, Hua Wang
Summary: This study presents a new strategy for designing efficient photocatalysts that can convert CO2 into hydrocarbons by utilizing synergistic catalytic sites. The findings provide a solution for the selective photocatalytic reduction of CO2 to CH4.
Article
Chemistry, Multidisciplinary
Chengxian Hu, Dan Wang, Lu Wang, Ying Fu, Zhengyin Du
Summary: A novel one-pot, three-component reaction conducted under electrochemical conditions was studied. The reaction involved 2-aminothiophenols, aldehydes, and malononitrile, using TBABF4 as an electrolyte and CuI as a catalyst. The proposed reaction mechanism suggested that CuI served as an electron relay. This method offers simplified operation, high atom economy, and mild reaction conditions.
Article
Chemistry, Multidisciplinary
Zhi Yang, Yu Chen, Linxi Wan, Yuxiao Li, Dan Chen, Jianlin Tao, Pei Tang, Fen-Er Chen
Summary: A highly enantioselective method for the complete hydrogenation of pyrimidinium salts using Ir/(S,S)-f-Binaphane complex as the catalyst was developed. This method provides easy access to fully saturated chiral hexahydropyrimidines, which are prevalent in many bioactive molecules. The reactions exhibit high yields and enantioselectivities under mild reaction conditions without additives. Successful application of this methodology in a continuous flow fashion further extends its practical utility.
Article
Chemistry, Multidisciplinary
Tina Jeoh, Jennifer Danger Nill, Wujun Zhao, Sankar Raju Narayanasamy, Liang Chen, Hoi-Ying N. Holman
Summary: In this study, the enzymatic hydrolysis of cellulose was investigated using real-time infrared spectromicroscopy. The spatial heterogeneity of cellulose was found to impact the hydrolysis kinetics. Hydration affected cellulose ordering, and Cel7A preferentially removed less extensively hydrogen bonded cellulose.
Article
Chemistry, Multidisciplinary
Tiphaine Richard, Walid Abdallah, Xavier Trivelli, Mathieu Sauthier, Clement Dumont
Summary: An effective method of grafting functionalities onto lignin based on glycerol carbonate has been developed using an efficient nickel-catalysed telomerisation reaction. This method allows lignin to have new reactive functions and reduces the glass transition temperatures of modified lignins, thereby expanding the application range of lignin-based resins.
Article
Chemistry, Multidisciplinary
Jing Qi, Xiyan Wang, Gan Wang, Srinivas Reddy Dubbaka, Patrick ONeill, Hwee Ting Ang, Jie Wu
Summary: This study presents a green and environmentally friendly approach for the synthesis of imides using electrocatalytic oxidation with H2O as the oxygen source. The method eliminates the need for toxic or expensive oxidants and achieves high yields under mild reaction conditions. It shows broad substrate compatibility and potential for industrial applications.
Article
Chemistry, Multidisciplinary
Babasaheb Sopan Gore, Lin-Wei Pan, Jun-Hao Lin, Yi-Chi Luo, Jeh-Jeng Wang
Summary: Here, we report a visible light-promoted intramolecular radical cascade reaction for the construction of fluorenol and naphthalene-fused cyclopropyl carbaldehyde derivatives. This method offers mild reaction conditions, a broad substrate scope, excellent step efficiency, and scalability, without the need for external chemical oxidants. The novelty of this protocol was demonstrated by synthesizing chrysene analogs and performing late-stage functionalizations.
Article
Chemistry, Multidisciplinary
Juho Antti Sirvio, Idamaria Romakkaniemi, Juha Ahola, Svitlana Filonenko, Juha P. Heiskanen, Ari Ammala
Summary: This article discusses the method of using supramolecular interaction between an aromatic hydrogen bond donor and lignin to achieve rapid delignification of softwood at low temperatures.
Article
Chemistry, Multidisciplinary
Yunyan Meng, Chunxiang Pan, Na Liu, Hongjiang Li, Zixiu Liu, Yao Deng, Zixiang Wei, Jianbin Xu, Baomin Fan
Summary: A novel visible light-driven synthesis method for 2,3-diamines has been developed, which has mild conditions, avoids the use of metal reagents, and can synthesize diamines and diols in one pot.
Article
Chemistry, Multidisciplinary
Mingqing Huang, Haiyang Huang, Mengyao You, Xinxin Zhang, Longgen Sun, Chao Chen, Zhichao Mei, Ruchun Yang, Qiang Xiao
Summary: A direct air-oxidized strategy for the synthesis of benzo[b]phosphole oxides was developed in this study. Arylphosphine oxides were transformed into phosphinoyl radicals, which were further combined with various alkynes to achieve the desired products. DFT calculations revealed the mechanism of phosphinoyl radical formation.
Article
Chemistry, Multidisciplinary
Anwei Wang, Jiayin Huang, Chunsheng Zhao, Yu Fan, Junfeng Qian, Qun Chen, Mingyang He, Weiyou Zhou
Summary: This study demonstrates an innovative strategy for the aerobic oxidation of C(sp(3))-H bonds using gamma-valerolactone. By optimizing the reaction conditions and utilizing specific catalysts, efficient oxidation of C(sp(3))-H bonds is achieved with good chemoselectivity in certain cases.
Article
Chemistry, Multidisciplinary
Shun Li, Likai Tong, Zhijian Peng, Bo Zhang, Xiuli Fu
Summary: Sulfide compounds show promise as electrocatalysts for water splitting, but their performance is limited by factors such as limited active sites and hindered substance transport. This study successfully prepared a high-entropy sulfide (ZnCoMnFeAlMg)(9)S-8, which reduced grain size and increased specific surface area, enabling the realization of a dual-functional catalyst with multiple catalytic sites. High entropy also modulated the electronic properties of sulfides, reducing the potential energy barrier for hydrolysis. This research introduces a new approach for functionalizing high entropy nanomaterials and improves the performance of water splitting catalysts.