4.8 Article

Rapid production of benzazole derivatives by a high-pressure and high-temperature water microflow chemical process

Journal

GREEN CHEMISTRY
Volume 18, Issue 12, Pages 3494-3498

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6gc01195k

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Funding

  1. JSPS KAKENHI Grant [15H06892]
  2. Grants-in-Aid for Scientific Research [15H06892] Funding Source: KAKEN

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A high-pressure and high-temperature (HPHT) water microflow chemical process was utilized for the synthesis of benzazole derivatives. The current approach enables the extremely rapid production of various 2-arylbenzazoles including benzimidazoles, benzoxazoles, and benzthiazole in excellent yields.

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