Muc5ac Production Inhibited by Decreased lncRNA H19 via PI3K/Akt/NF-kB in Asthma

P38 MAPK and glucocorticoid receptor crosstalk in bronchial epithelial cells

(2020) Simon Lea et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice

(2020) Zhirong Jia et al.   Mucosal Immunology

Long noncoding RNA Q associates with Sox2 and is involved in the maintenance of pluripotency in mouse embryonic stem cells

(2020) Ruiqi Jing et al.   STEM CELLS

Streptococcus pneumoniae aminopeptidase N regulates dendritic cells that attenuates type‐2 airway inflammation in murine allergic asthma

(2020) Guangying Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lnc-BAZ2B promotes M2 macrophage activation and inflammation in asthmatic children through stabilizing BAZ2B pre-mRNA

(2020) Li Xia et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Bergenin-activated SIRT1 inhibits TNF-α-induced proinflammatory response by blocking the NF-κB signaling pathway

(2020) Min Chen et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Analysis of lncRNA Expression in Patients With Eosinophilic and Neutrophilic Asthma Focusing on LNC_000127

(2019) Yujin Zhu et al.   Frontiers in Genetics

The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration

(2019) Daniel T. Swarr et al.   GENES & DEVELOPMENT

Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production

(2019) Md. Samsuzzaman et al.   LIFE SCIENCES

Cucurbitacin E ameliorates lipopolysaccharide-evoked injury, inflammation and MUC5AC expression in bronchial epithelial cells by restraining the HMGB1-TLR4-NF-κB signaling

(2019) Jin Shang et al.   MOLECULAR IMMUNOLOGY

Macrophages-induced long noncoding RNA H19 up-regulation triggers and activates the miR-193b/MAPK1 axis and promotes cell aggressiveness in hepatocellular carcinoma

(2019) Yingnan Ye et al.   CANCER LETTERS

LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE

(2019) Xiao Han et al.   Science Advances

Intranasal administration of recombinant progranulin inhibits bronchial smooth muscle hyperresponsiveness in mouse allergic asthma

(2018) Yoshihiko Chiba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Peripheral whole blood lncRNA expression analysis in patients with eosinophilic asthma

(2018) Yu-Jin Zhu et al.   MEDICINE

GAS5 promotes airway smooth muscle cell proliferation in asthma via controlling miR-10a/BDNF signaling pathway

(2018) Xiao-yu Zhang et al.   LIFE SCIENCES

Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation ( PVT1 ) as a novel regulator of the asthmatic phenotype in human airway smooth muscle

(2017) Philip J. Austin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma

(2017) Xing Wang et al.   EBioMedicine

Airway Mucus and Asthma: The Role of MUC5AC and MUC5B

(2017) Luke Bonser et al.   Journal of Clinical Medicine

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma

(2016) Marrah E. Lachowicz-Scroggins et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Verproside inhibits TNF-α-induced MUC5AC expression through suppression of the TNF-α/NF-κB pathway in human airway epithelial cells

(2016) Su Ui Lee et al.   CYTOKINE

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

(2016) Jonathan J. Kotzin et al.   NATURE

A human monoclonal anti-TNF alpha antibody (adalimumab) reduces airway inflammation and ameliorates lung histology in a murine model of acute asthma

(2015) F. Catal et al.   ALLERGOLOGIA ET IMMUNOPATHOLOGIA

Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB

(2015) T. Xie et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Flavonoid 7,4′-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-κB, STAT6, and HDAC2

(2015) Changda Liu et al.   PHYTOTHERAPY RESEARCH

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

(2015) Christopher M. Evans et al.   Nature Communications

The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration

(2014) B. K. Dey et al.   GENES & DEVELOPMENT

Melatonin inhibits MUC5AC production via suppression of MAPK signaling in human airway epithelial cells

(2014) In-Sik Shin et al.   JOURNAL OF PINEAL RESEARCH

Long non-coding RNAs in the regulation of the immune response

(2014) James A. Heward et al.   TRENDS IN IMMUNOLOGY

Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages

(2013) Supriya R. Hyam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of mammalian cell differentiation by long non-coding RNAs

(2012) Wenqian Hu et al.   EMBO REPORTS

Locally instilled tumor necrosis factor-α antisense oligonucleotide inhibits allergic inflammation via the induction of Tregs

(2012) Yi Luo et al.   JOURNAL OF GENE MEDICINE

Anti-arthritic effects of clematichinenoside (AR-6) on PI3K/Akt signaling pathway and TNF-α associated with collagen-induced arthritis

(2012) Wang Han et al.   PHARMACEUTICAL BIOLOGY

Infliximab alleviates inflammation and ex vivo airway hyperreactivity in asthmatic E3 rats

(2011) Y. Cai et al.   INTERNATIONAL IMMUNOLOGY

Asthma

(2009) Christopher H. Fanta   NEW ENGLAND JOURNAL OF MEDICINE