Characterization of Tumor-Associated Macrophages and the Immune Microenvironment in Limited-Stage Neuroendocrine-High and -Low Small Cell Lung Cancer

Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

(2021) Carl M. Gay et al.   CANCER CELL

Intrinsic immunogenicity of small cell lung carcinoma revealed by its cellular plasticity

(2021) Navin R. Mahadevan et al.   Cancer Discovery

Tumor Immunology and Tumor Evolution: Intertwined Histories

(2020) Jérôme Galon et al.   IMMUNITY

Evaluating the Polarization of Tumor-Associated Macrophages Into M1 and M2 Phenotypes in Human Cancer Tissue: Technicalities and Challenges in Routine Clinical Practice

(2020) Sharmilla Devi Jayasingam et al.   Frontiers in Oncology

Comparative expression analysis in small cell lung carcinoma reveals neuroendocrine pattern change in primary tumor versus lymph node metastases

(2020) Zoltan Lohinai et al.   Translational Lung Cancer Research

MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

(2020) Abbie S. Ireland et al.   CANCER CELL

Neuroendocrine subtypes of small cell lung cancer differ in terms of immune microenvironment and checkpoint molecule distribution

(2020) David Dora et al.   Molecular Oncology

Targeting Tumor-Associated Macrophages in Cancer

(2019) Paulina Pathria et al.   TRENDS IN IMMUNOLOGY

The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance

(2019) Amy Cooke et al.   Cell Reports

The Two Faces of Tumor-Associated Macrophages and Their Clinical Significance in Colorectal Cancer

(2019) Marta L. Pinto et al.   Frontiers in Immunology

Immune Heterogeneity Between Primary Tumors and Corresponding Metastatic Lesions and Response to Platinum Therapy in Primary Ovarian Cancer

(2019) Katharina Dötzer et al.   Cancers

Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial

(2019) Luis Paz-Ares et al.   LANCET

MHC-II neoantigens shape tumour immunity and response to immunotherapy

(2019) Elise Alspach et al.   NATURE

Circulating and Tumor Myeloid-derived Suppressor Cells in Resectable Non-small-cell Lung Cancer

(2018) Yoshikane Yamauchi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Immunological differences between primary and metastatic breast cancer

(2018) B Szekely et al.   ANNALS OF ONCOLOGY

First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer

(2018) Leora Horn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expression of the MHC class II in triple-negative breast cancer is associated with tumor-infiltrating lymphocytes and interferon signaling

(2017) In Ah Park et al.   PLoS One

Eight potential biomarkers for distinguishing between lung adenocarcinoma and squamous cell carcinoma

(2017) Jian Xiao et al.   Oncotarget

Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy

(2017) Xiang Zheng et al.   Oncotarget

Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment

(2017) Leonardo A. Moraes et al.   Scientific Reports

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

CD68/macrosialin: not just a histochemical marker

(2016) Dimitry A Chistiakov et al.   LABORATORY INVESTIGATION

ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs

(2016) Mark D. Borromeo et al.   Cell Reports

Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes

(2016) A. Forero et al.   Cancer Immunology Research

Regulation of Tumor Metastasis by Myeloid-Derived Suppressor Cells

(2015) Thomas Condamine et al.   Annual Review of Medicine

Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair

(2015) Giovanna Leoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloid derived suppressor cell infiltration of murine and human gliomas is associated with reduction of tumor infiltrating lymphocytes

(2015) Baisakhi Raychaudhuri et al.   JOURNAL OF NEURO-ONCOLOGY

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

(2015) G. Wang et al.   Cancer Discovery

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

(2015) Julie Jacobs et al.   Oncotarget

Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer

(2015) Tommaso De Marchi et al.   Oncotarget

Annexin A1 in primary tumors promotes melanoma dissemination

(2014) Zied Boudhraa et al.   CLINICAL & EXPERIMENTAL METASTASIS

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Increased expression of annexin A1 predicts poor prognosis in human hepatocellular carcinoma and enhances cell malignant phenotype

(2014) Ya Lin et al.   MEDICAL ONCOLOGY

Overexpression of ANXA1 confers independent negative prognostic impact in rectal cancers receiving concurrent chemoradiotherapy

(2014) Ming-Jen Sheu et al.   TUMOR BIOLOGY

Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment

(2014) Theerawut Chanmee et al.   Cancers

Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer

(2013) J. Yu et al.   JOURNAL OF IMMUNOLOGY

Semaphorin 4D cooperates with VEGF to promote angiogenesis and tumor progression

(2012) Hua Zhou et al.   ANGIOGENESIS

Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway

(2012) Tsu-Yao Cheng et al.   CANCER

Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth

(2012) Matthew R. Porembka et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth

(2012) C. Claus et al.   CANCER RESEARCH

CXCR3 Chemokine Receptor-Ligand Interactions in the Lymph Node Optimize CD4+ T Helper 1 Cell Differentiation

(2012) Joanna R. Groom et al.   IMMUNITY

Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients

(2012) Rong Biaoxue et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Molecular Characteristics and Metastasis Predictor Genes of Triple-Negative Breast Cancer: A Clinical Study of Triple-Negative Breast Carcinomas

(2012) Wen-Hung Kuo et al.   PLoS One

A novel role for granzymes in anti-tumor immunity

(2012) Sabine Hoves et al.   OncoImmunology

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

Maximal T Cell-Mediated Antitumor Responses Rely upon CCR5 Expression in Both CD4+ and CD8+ T Cells

(2011) A. Gonzalez-Martin et al.   CANCER RESEARCH

Functional Characteristics of the High Affinity IgG Receptor, Fc RI

(2011) C. E. van der Poel et al.   JOURNAL OF IMMUNOLOGY

Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis

(2011) P Bist et al.   ONCOGENE

Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2010) M. Sorensen et al.   ANNALS OF ONCOLOGY

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Annexin A1 regulates TGF-  signaling and promotes metastasis formation of basal-like breast cancer cells

(2010) M. de Graauw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology

(2009) Martijn A. Nolte et al.   IMMUNOLOGICAL REVIEWS

Dendritic cells integrate signals from the tumor microenvironment to modulate immunity and tumor growth

(2009) Albert Lin et al.   IMMUNOLOGY LETTERS

Predictive value of MMP-7 expression for response to chemotherapy and survival in patients with non-small cell lung cancer

(2008) Hui Liu et al.   CANCER SCIENCE